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Atomistry » Zinc » PDB 5msb-5n2x » 5mxr | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Zinc » PDB 5msb-5n2x » 5mxr » |
Zinc in PDB 5mxr: Crystal Structure of the Acquired Vim-2 Metallo-Beta-Lactamase in Complex with Ant-330 InhibitorProtein crystallography data
The structure of Crystal Structure of the Acquired Vim-2 Metallo-Beta-Lactamase in Complex with Ant-330 Inhibitor, PDB code: 5mxr
was solved by
J.D.Docquier,
F.De Luca,
M.Benvenuti,
F.Di Pisa,
C.Pozzi,
S.Mangani,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Zinc Binding Sites:
The binding sites of Zinc atom in the Crystal Structure of the Acquired Vim-2 Metallo-Beta-Lactamase in Complex with Ant-330 Inhibitor
(pdb code 5mxr). This binding sites where shown within
5.0 Angstroms radius around Zinc atom.
In total 3 binding sites of Zinc where determined in the Crystal Structure of the Acquired Vim-2 Metallo-Beta-Lactamase in Complex with Ant-330 Inhibitor, PDB code: 5mxr: Jump to Zinc binding site number: 1; 2; 3; Zinc binding site 1 out of 3 in 5mxrGo back to Zinc Binding Sites List in 5mxr
Zinc binding site 1 out
of 3 in the Crystal Structure of the Acquired Vim-2 Metallo-Beta-Lactamase in Complex with Ant-330 Inhibitor
Mono view Stereo pair view
Zinc binding site 2 out of 3 in 5mxrGo back to Zinc Binding Sites List in 5mxr
Zinc binding site 2 out
of 3 in the Crystal Structure of the Acquired Vim-2 Metallo-Beta-Lactamase in Complex with Ant-330 Inhibitor
Mono view Stereo pair view
Zinc binding site 3 out of 3 in 5mxrGo back to Zinc Binding Sites List in 5mxr
Zinc binding site 3 out
of 3 in the Crystal Structure of the Acquired Vim-2 Metallo-Beta-Lactamase in Complex with Ant-330 Inhibitor
Mono view Stereo pair view
Reference:
S.Leiris,
A.Coelho,
J.Castandet,
M.Bayet,
C.Lozano,
J.Bougnon,
J.Bousquet,
M.Everett,
M.Lemonnier,
N.Sprynski,
M.Zalacain,
T.D.Pallin,
M.C.Cramp,
N.Jennings,
G.Raphy,
M.W.Jones,
R.Pattipati,
B.Shankar,
R.Sivasubrahmanyam,
A.K.Soodhagani,
R.R.Juventhala,
N.Pottabathini,
S.Pothukanuri,
M.Benvenuti,
C.Pozzi,
S.Mangani,
F.De Luca,
G.Cerboni,
J.D.Docquier,
D.T.Davies.
Sar Studies Leading to the Identification of A Novel Series of Metallo-Beta-Lactamase Inhibitors For the Treatment of Carbapenem-Resistant Enterobacteriaceae Infections That Display Efficacy in An Animal Infection Model. Acs Infect Dis. V. 5 131 2019.
Page generated: Sun Oct 27 22:23:39 2024
ISSN: ESSN 2373-8227 PubMed: 30427656 DOI: 10.1021/ACSINFECDIS.8B00246 |
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