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Zinc in PDB 5mnr: Thermolysin in Complex with Inhibitor JC256Enzymatic activity of Thermolysin in Complex with Inhibitor JC256
All present enzymatic activity of Thermolysin in Complex with Inhibitor JC256:
3.4.24.27; Protein crystallography data
The structure of Thermolysin in Complex with Inhibitor JC256, PDB code: 5mnr
was solved by
J.Cramer,
S.G.Krimmer,
A.Heine,
G.Klebe,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 5mnr:
The structure of Thermolysin in Complex with Inhibitor JC256 also contains other interesting chemical elements:
Zinc Binding Sites:
The binding sites of Zinc atom in the Thermolysin in Complex with Inhibitor JC256
(pdb code 5mnr). This binding sites where shown within
5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Thermolysin in Complex with Inhibitor JC256, PDB code: 5mnr: Zinc binding site 1 out of 1 in 5mnrGo back to Zinc Binding Sites List in 5mnr
Zinc binding site 1 out
of 1 in the Thermolysin in Complex with Inhibitor JC256
Mono view Stereo pair view
Reference:
J.Cramer,
S.G.Krimmer,
A.Heine,
G.Klebe.
Paying the Price of Desolvation in Solvent-Exposed Protein Pockets: Impact of Distal Solubilizing Groups on Affinity and Binding Thermodynamics in A Series of Thermolysin Inhibitors. J. Med. Chem. V. 60 5791 2017.
Page generated: Wed Dec 16 06:33:26 2020
ISSN: ISSN 1520-4804 PubMed: 28590130 DOI: 10.1021/ACS.JMEDCHEM.7B00490 |
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