Zinc in PDB 5lst: Crystal Structure of the Human RECQL4 Helicase.

All present enzymatic activity of Crystal Structure of the Human RECQL4 Helicase.:
3.6.4.12;

The structure of Crystal Structure of the Human RECQL4 Helicase., PDB code: 5lst was solved by S.Kaiser, F.Sauer, C.Kisker, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	44.34 / 2.75
Space group	P 31 2 1
Cell size a, b, c (Å), α, β, γ (°)	131.001, 131.001, 96.344, 90.00, 90.00, 120.00
R / Rfree (%)	18.3 / 23.1

The binding sites of Zinc atom in the Crystal Structure of the Human RECQL4 Helicase. (pdb code 5lst). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Crystal Structure of the Human RECQL4 Helicase., PDB code: 5lst:

Zinc binding site 1 out of 1 in the Crystal Structure of the Human RECQL4 Helicase.


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure of the Human RECQL4 Helicase. within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn1201 b:83.1 occ:1.00 NE2 A:HIS900 2.0 77.5 1.0 SG A:CYS853 2.3 89.3 1.0 SG A:CYS897 2.3 80.1 1.0 SG A:CYS855 2.4 96.2 1.0 CD2 A:HIS900 3.0 79.8 1.0 CE1 A:HIS900 3.0 81.2 1.0 CB A:CYS897 3.2 82.5 1.0 CB A:CYS853 3.2 81.0 1.0 CB A:CYS855 3.3 94.3 1.0 CA A:CYS897 3.8 89.8 1.0 ND1 A:HIS900 4.1 85.5 1.0 CG A:HIS900 4.1 83.6 1.0 N A:CYS855 4.4 92.1 1.0 CA A:CYS855 4.5 89.1 1.0 N A:GLY1041 4.5 85.1 1.0 CA A:GLY1041 4.6 90.4 1.0 C A:CYS897 4.7 90.1 1.0 CA A:CYS853 4.7 85.8 1.0 N A:MET898 4.8 92.5 1.0 N A:CYS897 4.9 85.6 1.0 C A:GLY1041 5.0 91.3 1.0 N A:GLY899 5.0 78.6 1.0

S.Kaiser, F.Sauer, C.Kisker. The Structural and Functional Characterization of Human RECQ4 Reveals Insights Into Its Helicase Mechanism. Nat Commun V. 8 15907 2017.
ISSN: ESSN 2041-1723
PubMed: 28653661
DOI: 10.1038/NCOMMS15907