Zinc in PDB 5iea: TRIM5 B-BOX2 and Coiled-Coil Chimera

All present enzymatic activity of TRIM5 B-BOX2 and Coiled-Coil Chimera:
6.1.1.11;

The structure of TRIM5 B-BOX2 and Coiled-Coil Chimera, PDB code: 5iea was solved by J.M.Wagner, G.Doss, O.Pornillos, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	36.70 / 3.26
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	71.227, 71.486, 213.834, 90.00, 90.00, 90.00
R / Rfree (%)	26 / 30.4

Pages:

>>> Page 1 <<< Page 2, Binding sites: 11 - 12;

Binding sites:

The binding sites of Zinc atom in the TRIM5 B-BOX2 and Coiled-Coil Chimera (pdb code 5iea). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 12 binding sites of Zinc where determined in the TRIM5 B-BOX2 and Coiled-Coil Chimera, PDB code: 5iea:
Jump to Zinc binding site number: 1; 2; 3; 4; 5; 6; 7; 8; 9; 10;

Zinc binding site 1 out of 12 in the TRIM5 B-BOX2 and Coiled-Coil Chimera


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of TRIM5 B-BOX2 and Coiled-Coil Chimera within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn701 b:43.4 occ:1.00 OD2 A:ASP111 2.0 54.9 1.0 ND1 A:HIS128 2.0 40.2 1.0 ND1 A:HIS125 2.0 30.4 1.0 SG A:CYS108 2.2 57.0 1.0 CE1 A:HIS128 2.8 43.0 1.0 HE1 A:HIS128 2.8 51.6 1.0 HB3 A:HIS125 2.9 37.5 1.0 CG A:ASP111 3.0 85.1 1.0 CG A:HIS125 3.0 29.6 1.0 CE1 A:HIS125 3.0 30.2 1.0 HB2 A:ASP111 3.1 0.4 1.0 HA A:HIS125 3.1 42.5 1.0 CG A:HIS128 3.2 34.3 1.0 HE1 A:HIS125 3.2 36.2 1.0 CB A:HIS125 3.3 31.2 1.0 CB A:CYS108 3.4 46.3 1.0 H A:ASP111 3.4 60.8 1.0 HB2 A:CYS108 3.4 55.6 1.0 HB3 A:CYS108 3.5 55.6 1.0 HB2 A:HIS128 3.6 41.3 1.0 CB A:ASP111 3.6 93.7 1.0 HB3 A:HIS128 3.6 41.3 1.0 CB A:HIS128 3.7 34.4 1.0 CA A:HIS125 3.7 35.4 1.0 OD1 A:ASP111 4.0 97.0 1.0 NE2 A:HIS128 4.0 40.9 1.0 HB2 A:GLU110 4.0 95.2 1.0 N A:ASP111 4.1 50.7 1.0 NE2 A:HIS125 4.1 29.2 1.0 CD2 A:HIS125 4.1 28.8 1.0 CD2 A:HIS128 4.2 34.5 1.0 HB2 A:HIS125 4.2 37.5 1.0 HB3 A:ASP111 4.3 0.4 1.0 HD13 A:ILE115 4.3 32.8 1.0 CA A:ASP111 4.5 77.8 1.0 O A:HIS125 4.6 30.3 1.0 C A:HIS125 4.7 29.8 1.0 O A:GLU124 4.7 35.6 1.0 HE2 A:HIS128 4.7 49.0 1.0 CA A:CYS108 4.7 31.1 1.0 N A:HIS125 4.8 35.4 1.0 HE2 A:HIS125 4.9 35.0 1.0 CB A:GLU110 4.9 79.3 1.0 HA A:CYS108 4.9 37.4 1.0 HD2 A:HIS125 5.0 34.5 1.0

Zinc binding site 2 out of 12 in the TRIM5 B-BOX2 and Coiled-Coil Chimera


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of TRIM5 B-BOX2 and Coiled-Coil Chimera within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn702 b:0.3 occ:1.00 ND1 A:HIS100 2.0 36.6 1.0 SG A:CYS116 2.2 59.7 1.0 SG A:CYS97 2.2 70.2 1.0 SG A:CYS119 2.2 41.6 1.0 HB2 A:HIS100 2.8 0.4 1.0 CE1 A:HIS100 2.9 71.5 1.0 CG A:HIS100 3.0 52.5 1.0 HE1 A:HIS100 3.1 85.8 1.0 H A:CYS119 3.2 63.4 1.0 CB A:CYS97 3.3 72.6 1.0 HB2 A:CYS97 3.4 87.1 1.0 CB A:HIS100 3.4 89.5 1.0 HB3 A:CYS97 3.4 87.1 1.0 CB A:CYS119 3.5 42.3 1.0 H A:HIS100 3.5 0.5 1.0 H A:CYS116 3.6 36.9 1.0 HB2 A:CYS119 3.6 50.8 1.0 HB2 A:LEU118 3.7 29.5 1.0 N A:CYS119 3.8 52.9 1.0 CB A:CYS116 3.9 63.4 1.0 NE2 A:HIS100 4.0 72.2 1.0 N A:HIS100 4.0 0.4 1.0 HB3 A:CYS116 4.1 76.0 1.0 CA A:CYS119 4.1 46.3 1.0 CD2 A:HIS100 4.1 62.9 1.0 HB3 A:HIS100 4.1 0.4 1.0 HA A:CYS119 4.2 55.6 1.0 HB3 A:CYS119 4.3 50.8 1.0 N A:CYS116 4.3 30.8 1.0 CA A:HIS100 4.3 0.9 1.0 HB2 A:CYS116 4.5 76.0 1.0 H A:ARG99 4.6 93.0 1.0 HB2 A:GLU102 4.6 87.5 1.0 CB A:LEU118 4.6 24.6 1.0 CA A:CYS116 4.6 38.7 1.0 H A:GLU102 4.6 43.8 1.0 CB A:ARG99 4.6 40.3 1.0 C A:LEU118 4.7 25.8 1.0 H A:GLY101 4.7 0.6 1.0 CA A:CYS97 4.7 73.8 1.0 HB3 A:LEU118 4.8 29.5 1.0 HE2 A:HIS100 4.8 86.7 1.0 HD12 A:LEU118 4.9 78.4 1.0 C A:ARG99 4.9 99.5 1.0 O A:CYS116 4.9 39.9 1.0 HB A:ILE115 4.9 31.8 1.0 C A:CYS116 4.9 30.3 1.0 HD2 A:HIS100 4.9 75.4 1.0 HA A:CYS97 5.0 88.5 1.0 H A:LEU118 5.0 31.1 1.0

Zinc binding site 3 out of 12 in the TRIM5 B-BOX2 and Coiled-Coil Chimera


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 3 of TRIM5 B-BOX2 and Coiled-Coil Chimera within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn701 b:54.2 occ:1.00 OD2 B:ASP111 2.0 63.7 1.0 ND1 B:HIS125 2.0 49.5 1.0 ND1 B:HIS128 2.1 69.0 1.0 SG B:CYS108 2.3 49.9 1.0 HE1 B:HIS128 2.7 96.2 1.0 CE1 B:HIS128 2.7 80.2 1.0 HB3 B:HIS125 2.9 62.0 1.0 CE1 B:HIS125 3.0 48.7 1.0 CG B:HIS125 3.0 50.5 1.0 CG B:ASP111 3.0 60.7 1.0 HB2 B:ASP111 3.1 73.4 1.0 HA B:HIS125 3.1 64.5 1.0 HE1 B:HIS125 3.2 58.5 1.0 CG B:HIS128 3.3 54.2 1.0 CB B:HIS125 3.3 51.6 1.0 CB B:CYS108 3.4 51.5 1.0 HB2 B:CYS108 3.5 61.8 1.0 HB3 B:CYS108 3.5 61.8 1.0 H B:ASP111 3.5 69.1 1.0 CB B:ASP111 3.6 61.1 1.0 HB2 B:HIS128 3.7 64.1 1.0 CA B:HIS125 3.8 53.7 1.0 HB3 B:HIS128 3.8 64.1 1.0 CB B:HIS128 3.9 53.4 1.0 NE2 B:HIS128 3.9 80.6 1.0 OD1 B:ASP111 4.0 60.3 1.0 NE2 B:HIS125 4.1 49.1 1.0 CD2 B:HIS125 4.1 50.2 1.0 HD13 B:ILE115 4.2 55.4 1.0 CD2 B:HIS128 4.2 65.8 1.0 HB2 B:HIS125 4.3 62.0 1.0 N B:ASP111 4.3 57.6 1.0 HB3 B:ASP111 4.3 73.4 1.0 HB2 B:GLU110 4.3 83.9 1.0 CA B:ASP111 4.6 64.5 1.0 HE2 B:HIS128 4.6 96.7 1.0 O B:HIS125 4.7 54.0 1.0 O B:GLU124 4.7 0.4 1.0 C B:HIS125 4.7 54.9 1.0 N B:HIS125 4.8 54.8 1.0 CA B:CYS108 4.8 46.9 1.0 HE2 B:HIS125 4.9 58.9 1.0 HD2 B:HIS125 5.0 60.2 1.0

Zinc binding site 4 out of 12 in the TRIM5 B-BOX2 and Coiled-Coil Chimera


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 4 of TRIM5 B-BOX2 and Coiled-Coil Chimera within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn702 b:73.5 occ:1.00 ND1 B:HIS100 2.1 66.5 1.0 SG B:CYS116 2.3 56.6 1.0 SG B:CYS119 2.3 57.0 1.0 SG B:CYS97 2.4 83.2 1.0 HB2 B:HIS100 2.7 88.5 1.0 CG B:HIS100 3.0 68.9 1.0 CE1 B:HIS100 3.0 56.8 1.0 HE1 B:HIS100 3.2 68.2 1.0 HB3 B:CYS97 3.2 93.7 1.0 CB B:CYS97 3.3 78.1 1.0 HB2 B:CYS97 3.3 93.7 1.0 CB B:HIS100 3.3 73.7 1.0 H B:CYS119 3.4 74.2 1.0 H B:CYS116 3.5 63.5 1.0 H B:HIS100 3.5 92.9 1.0 CB B:CYS119 3.6 61.3 1.0 HB2 B:CYS119 3.7 73.6 1.0 HB2 B:LEU118 3.8 61.0 1.0 N B:CYS119 3.9 61.8 1.0 CB B:CYS116 3.9 55.0 1.0 N B:HIS100 4.0 77.5 1.0 HB3 B:HIS100 4.0 88.5 1.0 HB3 B:CYS116 4.1 66.0 1.0 NE2 B:HIS100 4.1 59.0 1.0 CD2 B:HIS100 4.1 63.9 1.0 CA B:CYS119 4.2 68.0 1.0 N B:CYS116 4.3 52.9 1.0 CA B:HIS100 4.3 91.2 1.0 HA B:CYS119 4.3 81.5 1.0 HB3 B:CYS119 4.4 73.6 1.0 HB2 B:GLU102 4.6 97.1 1.0 H B:GLU102 4.6 78.6 1.0 HB2 B:CYS116 4.6 66.0 1.0 CA B:CYS116 4.6 53.1 1.0 H B:ARG99 4.6 95.8 1.0 CB B:ARG99 4.7 58.5 1.0 H B:GLY101 4.7 0.6 1.0 CA B:CYS97 4.7 78.9 1.0 CB B:LEU118 4.7 50.8 1.0 C B:LEU118 4.8 51.5 1.0 HE2 B:HIS100 4.9 70.8 1.0 HB B:ILE115 4.9 53.4 1.0 C B:ARG99 4.9 64.1 1.0 HA B:ILE115 4.9 51.6 1.0 HD2 B:HIS100 4.9 76.7 1.0 HB3 B:LEU118 4.9 61.0 1.0 HD12 B:LEU118 5.0 60.0 1.0 O B:CYS116 5.0 78.9 1.0 C B:CYS116 5.0 64.1 1.0

Zinc binding site 5 out of 12 in the TRIM5 B-BOX2 and Coiled-Coil Chimera


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 5 of TRIM5 B-BOX2 and Coiled-Coil Chimera within 5.0Å range: probe atom residue distance (Å) B Occ C:Zn701 b:47.2 occ:1.00 OD2 C:ASP111 2.0 63.3 1.0 ND1 C:HIS128 2.0 40.9 1.0 ND1 C:HIS125 2.0 34.3 1.0 SG C:CYS108 2.2 65.9 1.0 CE1 C:HIS128 2.8 44.8 1.0 HE1 C:HIS128 2.8 53.7 1.0 CG C:ASP111 3.0 81.2 1.0 HB3 C:HIS125 3.0 48.2 1.0 CE1 C:HIS125 3.0 33.8 1.0 CG C:HIS125 3.0 33.6 1.0 HB2 C:ASP111 3.1 0.9 1.0 HA C:HIS125 3.1 50.9 1.0 HE1 C:HIS125 3.2 40.6 1.0 CG C:HIS128 3.2 41.4 1.0 H C:ASP111 3.4 69.7 1.0 CB C:HIS125 3.4 40.2 1.0 CB C:CYS108 3.5 52.3 1.0 HB2 C:CYS108 3.5 62.8 1.0 CB C:ASP111 3.6 92.4 1.0 HB2 C:HIS128 3.6 49.8 1.0 HB3 C:CYS108 3.6 62.8 1.0 HB3 C:HIS128 3.7 49.8 1.0 CB C:HIS128 3.8 41.5 1.0 CA C:HIS125 3.8 42.4 1.0 OD1 C:ASP111 3.9 81.6 1.0 NE2 C:HIS128 4.0 44.7 1.0 HB2 C:GLU110 4.0 80.4 1.0 N C:ASP111 4.1 58.0 1.0 NE2 C:HIS125 4.1 32.9 1.0 CD2 C:HIS125 4.2 32.9 1.0 CD2 C:HIS128 4.2 41.9 1.0 HB2 C:HIS125 4.3 48.2 1.0 HB3 C:ASP111 4.3 0.9 1.0 HD13 C:ILE115 4.4 38.6 1.0 CA C:ASP111 4.5 79.5 1.0 O C:HIS125 4.7 35.1 1.0 O C:GLU124 4.7 33.7 1.0 HE2 C:HIS128 4.7 53.7 1.0 C C:HIS125 4.7 34.9 1.0 N C:HIS125 4.8 39.5 1.0 CA C:CYS108 4.8 35.8 1.0 CB C:GLU110 4.8 67.0 1.0 HE2 C:HIS125 4.9 39.4 1.0 HB3 C:GLU110 4.9 80.4 1.0

Zinc binding site 6 out of 12 in the TRIM5 B-BOX2 and Coiled-Coil Chimera


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 6 of TRIM5 B-BOX2 and Coiled-Coil Chimera within 5.0Å range: probe atom residue distance (Å) B Occ C:Zn702 b:45.5 occ:1.00 ND1 C:HIS100 2.1 26.1 1.0 SG C:CYS97 2.2 63.2 1.0 SG C:CYS119 2.3 56.1 1.0 SG C:CYS116 2.3 68.4 1.0 HB2 C:HIS100 2.8 55.0 1.0 CE1 C:HIS100 3.0 41.9 1.0 CG C:HIS100 3.1 37.1 1.0 HE1 C:HIS100 3.2 50.3 1.0 CB C:CYS97 3.2 57.4 1.0 HB2 C:CYS97 3.2 68.9 1.0 HB3 C:CYS97 3.3 68.9 1.0 H C:CYS119 3.3 60.7 1.0 CB C:HIS100 3.4 45.9 1.0 H C:HIS100 3.4 0.4 1.0 H C:CYS116 3.6 40.8 1.0 CB C:CYS119 3.6 46.6 1.0 HB2 C:CYS119 3.6 55.9 1.0 HB2 C:LEU118 3.8 48.6 1.0 N C:CYS119 3.8 50.6 1.0 CB C:CYS116 3.9 72.3 1.0 N C:HIS100 4.0 92.8 1.0 NE2 C:HIS100 4.1 50.6 1.0 HB3 C:CYS116 4.1 86.8 1.0 CD2 C:HIS100 4.1 51.9 1.0 CA C:CYS119 4.2 44.7 1.0 HB3 C:HIS100 4.2 55.0 1.0 HA C:CYS119 4.2 53.6 1.0 CA C:HIS100 4.3 76.4 1.0 N C:CYS116 4.3 34.0 1.0 HB3 C:CYS119 4.4 55.9 1.0 H C:ARG99 4.5 72.8 1.0 H C:GLU102 4.6 57.9 1.0 CB C:ARG99 4.6 39.7 1.0 HB2 C:GLU102 4.6 99.1 1.0 HB2 C:CYS116 4.6 86.8 1.0 H C:GLY101 4.6 0.8 1.0 CA C:CYS116 4.6 52.4 1.0 CA C:CYS97 4.7 66.9 1.0 CB C:LEU118 4.7 40.5 1.0 C C:LEU118 4.8 28.6 1.0 C C:ARG99 4.8 90.1 1.0 HB3 C:LEU118 4.9 48.6 1.0 HE2 C:HIS100 4.9 60.7 1.0 HA C:CYS97 4.9 80.3 1.0 HB C:ILE115 4.9 37.0 1.0 HD12 C:LEU118 5.0 99.0 1.0 N C:ARG99 5.0 60.6 1.0 O C:CYS116 5.0 37.5 1.0

Zinc binding site 7 out of 12 in the TRIM5 B-BOX2 and Coiled-Coil Chimera


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 7 of TRIM5 B-BOX2 and Coiled-Coil Chimera within 5.0Å range: probe atom residue distance (Å) B Occ D:Zn701 b:70.6 occ:1.00 OD2 D:ASP111 2.0 0.5 1.0 ND1 D:HIS128 2.0 56.0 1.0 ND1 D:HIS125 2.0 61.6 1.0 SG D:CYS108 2.3 62.2 1.0 CE1 D:HIS128 2.7 69.5 1.0 HE1 D:HIS128 2.7 83.4 1.0 HB3 D:HIS125 2.9 70.2 1.0 HA D:HIS125 3.0 89.9 1.0 CG D:HIS125 3.0 61.5 1.0 CG D:ASP111 3.0 0.4 1.0 CE1 D:HIS125 3.0 65.3 1.0 HB2 D:ASP111 3.2 0.5 1.0 CG D:HIS128 3.2 55.2 1.0 CB D:HIS125 3.3 58.5 1.0 HE1 D:HIS125 3.3 78.4 1.0 H D:ASP111 3.4 0.6 1.0 CB D:CYS108 3.6 78.8 1.0 CA D:HIS125 3.6 74.9 1.0 HB2 D:HIS128 3.6 65.3 1.0 CB D:ASP111 3.6 0.7 1.0 HB2 D:CYS108 3.7 94.6 1.0 HB3 D:CYS108 3.7 94.6 1.0 CB D:HIS128 3.8 54.5 1.0 HB3 D:HIS128 3.8 65.3 1.0 NE2 D:HIS128 3.9 79.8 1.0 OD1 D:ASP111 4.0 0.9 1.0 HB2 D:GLU110 4.1 80.8 1.0 CD2 D:HIS125 4.1 68.8 1.0 NE2 D:HIS125 4.1 72.0 1.0 N D:ASP111 4.2 1.0 1.0 CD2 D:HIS128 4.2 81.0 1.0 HB2 D:HIS125 4.2 70.2 1.0 HB3 D:ASP111 4.4 0.5 1.0 O D:GLU124 4.5 77.3 1.0 HD13 D:ILE115 4.5 63.8 1.0 C D:HIS125 4.5 53.6 1.0 O D:HIS125 4.5 52.9 1.0 CA D:ASP111 4.6 0.0 1.0 N D:HIS125 4.6 91.2 1.0 HE2 D:HIS128 4.6 95.8 1.0 HE2 D:HIS125 4.9 86.4 1.0 CB D:GLU110 4.9 67.3 1.0 CA D:CYS108 4.9 72.3 1.0 HD2 D:HIS125 5.0 82.6 1.0 C D:GLU124 5.0 76.7 1.0

Zinc binding site 8 out of 12 in the TRIM5 B-BOX2 and Coiled-Coil Chimera


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 8 of TRIM5 B-BOX2 and Coiled-Coil Chimera within 5.0Å range: probe atom residue distance (Å) B Occ D:Zn702 b:77.0 occ:1.00 ND1 D:HIS100 2.1 78.2 1.0 SG D:CYS119 2.3 58.4 1.0 SG D:CYS116 2.3 0.8 1.0 SG D:CYS97 2.3 0.2 1.0 HB2 D:HIS100 2.8 0.8 1.0 CE1 D:HIS100 3.0 69.2 1.0 CG D:HIS100 3.1 79.7 1.0 HE1 D:HIS100 3.1 83.0 1.0 H D:CYS119 3.2 66.6 1.0 CB D:CYS97 3.4 0.2 1.0 HB2 D:CYS97 3.4 0.7 1.0 CB D:HIS100 3.4 94.8 1.0 HB3 D:CYS97 3.5 0.7 1.0 CB D:CYS119 3.5 75.7 1.0 HB2 D:CYS119 3.5 90.9 1.0 H D:CYS116 3.5 87.6 1.0 H D:HIS100 3.5 0.7 1.0 N D:CYS119 3.8 55.5 1.0 HB2 D:LEU118 3.8 60.8 1.0 CB D:CYS116 4.0 0.1 1.0 N D:HIS100 4.0 0.7 1.0 NE2 D:HIS100 4.1 65.0 1.0 CA D:CYS119 4.1 73.2 1.0 CD2 D:HIS100 4.1 66.2 1.0 HB3 D:HIS100 4.2 0.8 1.0 HA D:CYS119 4.2 87.8 1.0 HB3 D:CYS116 4.2 0.2 1.0 HB3 D:CYS119 4.3 90.9 1.0 N D:CYS116 4.3 73.0 1.0 CA D:HIS100 4.3 0.7 1.0 H D:ARG99 4.5 0.4 1.0 CB D:ARG99 4.5 57.9 1.0 HB2 D:CYS116 4.6 0.2 1.0 HB2 D:GLU102 4.6 0.3 1.0 CA D:CYS116 4.6 81.9 1.0 H D:GLU102 4.7 0.4 1.0 CB D:LEU118 4.7 50.7 1.0 C D:LEU118 4.7 51.3 1.0 H D:GLY101 4.8 0.5 1.0 HB D:ILE115 4.8 65.0 1.0 CA D:CYS97 4.8 0.5 1.0 HE2 D:HIS100 4.8 78.0 1.0 HB3 D:LEU118 4.9 60.8 1.0 C D:ARG99 4.9 93.3 1.0 O D:CYS116 4.9 78.5 1.0 C D:CYS116 5.0 74.3 1.0 HD2 D:HIS100 5.0 79.5 1.0 HA D:ILE115 5.0 65.1 1.0

Zinc binding site 9 out of 12 in the TRIM5 B-BOX2 and Coiled-Coil Chimera


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 9 of TRIM5 B-BOX2 and Coiled-Coil Chimera within 5.0Å range: probe atom residue distance (Å) B Occ F:Zn701 b:49.6 occ:1.00 OD2 F:ASP111 2.0 52.6 1.0 ND1 F:HIS125 2.0 45.8 1.0 ND1 F:HIS128 2.1 71.7 1.0 SG F:CYS108 2.2 50.8 1.0 HE1 F:HIS128 2.7 95.6 1.0 CE1 F:HIS128 2.7 79.7 1.0 CE1 F:HIS125 3.0 45.0 1.0 CG F:ASP111 3.0 56.8 1.0 HB3 F:HIS125 3.0 57.5 1.0 CG F:HIS125 3.0 46.7 1.0 HB2 F:ASP111 3.1 73.7 1.0 HE1 F:HIS125 3.1 54.0 1.0 HA F:HIS125 3.2 60.1 1.0 CG F:HIS128 3.3 55.4 1.0 CB F:CYS108 3.3 55.3 1.0 HB3 F:CYS108 3.4 66.4 1.0 CB F:HIS125 3.4 47.9 1.0 HB2 F:CYS108 3.4 66.4 1.0 H F:ASP111 3.5 60.5 1.0 CB F:ASP111 3.6 61.4 1.0 HB2 F:HIS128 3.8 62.5 1.0 CA F:HIS125 3.8 50.1 1.0 HB3 F:HIS128 3.8 62.5 1.0 CB F:HIS128 3.9 52.1 1.0 NE2 F:HIS128 3.9 77.6 1.0 OD1 F:ASP111 4.0 59.7 1.0 NE2 F:HIS125 4.1 45.3 1.0 CD2 F:HIS125 4.1 46.4 1.0 N F:ASP111 4.2 50.5 1.0 HB2 F:GLU110 4.2 94.5 1.0 HD13 F:ILE115 4.2 50.3 1.0 CD2 F:HIS128 4.2 61.1 1.0 HB3 F:ASP111 4.3 73.7 1.0 HB2 F:HIS125 4.3 57.5 1.0 CA F:ASP111 4.6 66.4 1.0 HE2 F:HIS128 4.7 93.1 1.0 O F:GLU124 4.7 84.3 1.0 CA F:CYS108 4.7 41.6 1.0 O F:HIS125 4.7 50.4 1.0 C F:HIS125 4.8 51.3 1.0 N F:HIS125 4.8 51.2 1.0 HE2 F:HIS125 4.9 54.4 1.0 HA F:CYS108 5.0 49.9 1.0

Zinc binding site 10 out of 12 in the TRIM5 B-BOX2 and Coiled-Coil Chimera


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 10 of TRIM5 B-BOX2 and Coiled-Coil Chimera within 5.0Å range: probe atom residue distance (Å) B Occ F:Zn702 b:72.2 occ:1.00 ND1 F:HIS100 2.1 59.2 1.0 SG F:CYS119 2.3 60.8 1.0 SG F:CYS116 2.3 48.9 1.0 SG F:CYS97 2.4 97.8 1.0 HB2 F:HIS100 2.7 87.3 1.0 CG F:HIS100 3.0 61.8 1.0 CE1 F:HIS100 3.0 56.2 1.0 HE1 F:HIS100 3.2 67.5 1.0 CB F:CYS97 3.3 94.1 1.0 HB3 F:CYS97 3.3 0.9 1.0 HB2 F:CYS97 3.3 0.9 1.0 CB F:HIS100 3.3 72.8 1.0 H F:CYS119 3.4 66.5 1.0 H F:CYS116 3.5 56.7 1.0 H F:HIS100 3.5 0.6 1.0 CB F:CYS119 3.6 68.3 1.0 HB2 F:CYS119 3.6 81.9 1.0 HB2 F:LEU118 3.9 54.5 1.0 N F:CYS119 3.9 55.4 1.0 CB F:CYS116 3.9 47.3 1.0 N F:HIS100 4.0 84.7 1.0 HB3 F:HIS100 4.1 87.3 1.0 HB3 F:CYS116 4.1 56.8 1.0 NE2 F:HIS100 4.1 55.7 1.0 CD2 F:HIS100 4.1 57.2 1.0 CA F:CYS119 4.2 70.9 1.0 N F:CYS116 4.3 47.2 1.0 CA F:HIS100 4.3 96.5 1.0 HA F:CYS119 4.3 85.1 1.0 HB3 F:CYS119 4.4 81.9 1.0 HB2 F:CYS116 4.6 56.8 1.0 H F:GLU102 4.6 85.0 1.0 HB2 F:GLU102 4.6 89.8 1.0 CA F:CYS116 4.6 47.4 1.0 H F:ARG99 4.6 0.2 1.0 CB F:ARG99 4.6 67.4 1.0 H F:GLY101 4.7 0.0 1.0 CA F:CYS97 4.7 86.1 1.0 CB F:LEU118 4.8 45.4 1.0 C F:LEU118 4.8 46.3 1.0 HE2 F:HIS100 4.9 66.8 1.0 HB F:ILE115 4.9 48.1 1.0 C F:ARG99 4.9 78.4 1.0 HA F:ILE115 4.9 46.1 1.0 HD2 F:HIS100 4.9 68.7 1.0 O F:CYS116 5.0 83.5 1.0 HB3 F:LEU118 5.0 54.5 1.0 C F:CYS116 5.0 68.6 1.0

J.M.Wagner, M.D.Roganowicz, K.Skorupka, S.L.Alam, D.E.Christensen, G.L.Doss, Y.Wan, G.A.Frank, B.K.Ganser-Pornillos, W.I.Sundquist, O.Pornillos. Mechanism of B-Box 2 Domain-Mediated Higher-Order Assembly of the Retroviral Restriction Factor TRIM5 Alpha. Elife V. 5 2016.
ISSN: ESSN 2050-084X
PubMed: 27253059
DOI: 10.7554/ELIFE.16309