Zinc in PDB 5g35: Structure of RAD14 in Complex with Acetylaminopyren-C8-Guanine Containing Dna

The structure of Structure of RAD14 in Complex with Acetylaminopyren-C8-Guanine Containing Dna, PDB code: 5g35 was solved by N.Simon, C.Ebert, S.Schneider, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	53.17 / 2.00
Space group	P 41
Cell size a, b, c (Å), α, β, γ (°)	53.170, 53.170, 131.307, 90.00, 90.00, 90.00
R / Rfree (%)	21.7 / 25.4

The binding sites of Zinc atom in the Structure of RAD14 in Complex with Acetylaminopyren-C8-Guanine Containing Dna (pdb code 5g35). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Structure of RAD14 in Complex with Acetylaminopyren-C8-Guanine Containing Dna, PDB code: 5g35:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Structure of RAD14 in Complex with Acetylaminopyren-C8-Guanine Containing Dna


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Structure of RAD14 in Complex with Acetylaminopyren-C8-Guanine Containing Dna within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn338 b:32.5 occ:1.00 SG A:CYS216 2.2 31.2 1.0 SG A:CYS191 2.3 33.1 1.0 SG A:CYS194 2.4 31.9 1.0 SG A:CYS213 2.4 27.2 1.0 CB A:CYS191 3.0 33.9 1.0 CB A:CYS216 3.1 32.4 1.0 CB A:CYS194 3.2 34.8 1.0 CB A:CYS213 3.4 27.1 1.0 N A:CYS194 3.5 36.1 1.0 CA A:CYS194 3.9 35.3 1.0 N A:CYS213 4.0 28.5 1.0 CA A:CYS213 4.2 28.4 1.0 CA A:CYS216 4.4 32.3 1.0 CB A:GLU193 4.4 37.8 1.0 CB A:ASN197 4.4 32.4 1.0 N A:CYS216 4.5 31.0 1.0 CA A:CYS191 4.5 34.9 1.0 C A:GLU193 4.6 38.0 1.0 ND2 A:ASN197 4.7 34.8 1.0 N A:GLU193 4.8 35.8 1.0 O A:CYS213 4.8 27.6 1.0 CA A:GLU193 4.9 36.5 1.0 C A:CYS213 4.9 28.7 1.0 C A:CYS194 4.9 35.2 1.0 C A:CYS191 5.0 36.8 1.0 N A:HIS195 5.0 34.7 1.0

Zinc binding site 2 out of 2 in the Structure of RAD14 in Complex with Acetylaminopyren-C8-Guanine Containing Dna


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Structure of RAD14 in Complex with Acetylaminopyren-C8-Guanine Containing Dna within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn338 b:34.3 occ:1.00 SG B:CYS216 2.2 34.3 1.0 SG B:CYS191 2.2 29.5 1.0 SG B:CYS194 2.3 30.6 1.0 SG B:CYS213 2.5 31.3 1.0 CB B:CYS191 3.1 31.0 1.0 CB B:CYS216 3.2 31.6 1.0 CB B:CYS194 3.2 33.6 1.0 CB B:CYS213 3.4 31.8 1.0 N B:CYS194 3.6 35.2 1.0 CA B:CYS194 3.9 34.8 1.0 N B:CYS213 4.1 33.4 1.0 CA B:CYS213 4.3 32.0 1.0 CA B:CYS216 4.3 31.8 1.0 N B:CYS216 4.4 29.3 1.0 ND2 B:ASN197 4.5 31.1 1.0 CB B:GLU193 4.5 37.0 1.0 CA B:CYS191 4.6 32.7 1.0 CB B:ASN197 4.6 34.4 1.0 C B:GLU193 4.7 37.1 1.0 C B:CYS213 4.9 31.3 1.0 C B:CYS194 4.9 36.9 1.0 O B:CYS213 4.9 28.5 1.0 N B:GLU193 4.9 37.6 1.0 CA B:GLU193 5.0 36.6 1.0 C B:CYS191 5.0 36.0 1.0

S.Schneider, N.Simon, C.Ebert. Structural Basis For Bulky Adduct Dna Lesion Recognition By the Nucleotide Excision Repair Protein RAD14. Chemistry V. 22 10782 2016.
ISSN: ISSN 0947-6539
PubMed: 27223336
DOI: 10.1002/CHEM.201602438