|
Atomistry » Zinc » PDB 5fvu-5fz5 » 5fvx | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Zinc » PDB 5fvu-5fz5 » 5fvx » |
Zinc in PDB 5fvx: Structure of Human Nnos R354A G357D Mutant Heme Domain in Complex with 6-(2-(5-(3-(Dimethylamino)Propyl) Pyridin-3-Yl)Ethyl)-4-Methylpyridin- 2-AmineProtein crystallography data
The structure of Structure of Human Nnos R354A G357D Mutant Heme Domain in Complex with 6-(2-(5-(3-(Dimethylamino)Propyl) Pyridin-3-Yl)Ethyl)-4-Methylpyridin- 2-Amine, PDB code: 5fvx
was solved by
H.Li,
T.L.Poulos,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 5fvx:
The structure of Structure of Human Nnos R354A G357D Mutant Heme Domain in Complex with 6-(2-(5-(3-(Dimethylamino)Propyl) Pyridin-3-Yl)Ethyl)-4-Methylpyridin- 2-Amine also contains other interesting chemical elements:
Zinc Binding Sites:
The binding sites of Zinc atom in the Structure of Human Nnos R354A G357D Mutant Heme Domain in Complex with 6-(2-(5-(3-(Dimethylamino)Propyl) Pyridin-3-Yl)Ethyl)-4-Methylpyridin- 2-Amine
(pdb code 5fvx). This binding sites where shown within
5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Structure of Human Nnos R354A G357D Mutant Heme Domain in Complex with 6-(2-(5-(3-(Dimethylamino)Propyl) Pyridin-3-Yl)Ethyl)-4-Methylpyridin- 2-Amine, PDB code: 5fvx: Zinc binding site 1 out of 1 in 5fvxGo back to Zinc Binding Sites List in 5fvx
Zinc binding site 1 out
of 1 in the Structure of Human Nnos R354A G357D Mutant Heme Domain in Complex with 6-(2-(5-(3-(Dimethylamino)Propyl) Pyridin-3-Yl)Ethyl)-4-Methylpyridin- 2-Amine
Mono view Stereo pair view
Reference:
H.Wang,
Y.Qin,
H.Li,
L.J.Roman,
P.Martasek,
T.L.Poulos,
R.B.Silverman.
Potent and Selective Human Neuronal Nitric Oxide Synthase Inhibition By Optimization of the 2-Aminopyridine-Based Scaffold with A Pyridine Linker. J.Med.Chem. V. 59 4913 2016.
Page generated: Wed Dec 16 06:16:55 2020
ISSN: ISSN 0022-2623 PubMed: 27050842 DOI: 10.1021/ACS.JMEDCHEM.6B00273 |
Last articlesZn in 8WB0Zn in 8WAX Zn in 8WAU Zn in 8WAZ Zn in 8WAY Zn in 8WAV Zn in 8WAW Zn in 8WAT Zn in 8W7M Zn in 8WD3 |
© Copyright 2008-2020 by atomistry.com | ||
Home | Site Map | Copyright | Contact us | Privacy |