Zinc in PDB 5frx: Crystal Structure of the Phenol-Responsive Sensory Domain of the Transcription Activator Poxr in Complex with 4-Nitrophenol

The structure of Crystal Structure of the Phenol-Responsive Sensory Domain of the Transcription Activator Poxr in Complex with 4-Nitrophenol, PDB code: 5frx was solved by V.V.Patil, E.J.Woo, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	36.29 / 2.40
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	46.241, 70.470, 105.236, 90.00, 90.00, 90.00
R / Rfree (%)	20.6 / 28.8

The binding sites of Zinc atom in the Crystal Structure of the Phenol-Responsive Sensory Domain of the Transcription Activator Poxr in Complex with 4-Nitrophenol (pdb code 5frx). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Crystal Structure of the Phenol-Responsive Sensory Domain of the Transcription Activator Poxr in Complex with 4-Nitrophenol, PDB code: 5frx:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Crystal Structure of the Phenol-Responsive Sensory Domain of the Transcription Activator Poxr in Complex with 4-Nitrophenol


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure of the Phenol-Responsive Sensory Domain of the Transcription Activator Poxr in Complex with 4-Nitrophenol within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn1209 b:48.8 occ:1.00 OE1 A:GLU174 1.9 46.4 1.0 SG A:CYS185 2.2 51.9 1.0 SG A:CYS151 2.3 46.4 1.0 SG A:CYS177 2.5 52.1 1.0 CD A:GLU174 2.9 45.8 1.0 CB A:CYS185 3.3 57.0 1.0 OE2 A:GLU174 3.3 46.8 1.0 CB A:CYS177 3.4 50.3 1.0 CB A:CYS151 3.4 39.7 1.0 CA A:CYS177 3.7 56.4 1.0 N A:VAL178 4.0 58.4 1.0 N A:CYS151 4.1 46.6 1.0 OG A:SER133 4.3 48.4 1.0 C A:CYS177 4.3 61.2 1.0 CG A:GLU174 4.3 44.6 1.0 CA A:CYS151 4.4 40.9 1.0 CA A:CYS185 4.4 59.2 1.0 CG2 A:VAL178 4.4 63.7 1.0 CE3 A:TRP130 4.6 41.9 1.0 O A:GLU176 4.7 59.5 1.0 N A:GLY179 4.7 59.5 1.0 N A:VAL150 4.7 48.3 1.0 CB A:SER133 4.7 46.2 1.0 CZ3 A:TRP130 4.8 42.9 1.0 CG2 A:VAL150 4.9 49.3 1.0 N A:CYS177 5.0 60.7 1.0

Zinc binding site 2 out of 2 in the Crystal Structure of the Phenol-Responsive Sensory Domain of the Transcription Activator Poxr in Complex with 4-Nitrophenol


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Crystal Structure of the Phenol-Responsive Sensory Domain of the Transcription Activator Poxr in Complex with 4-Nitrophenol within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn1209 b:52.8 occ:1.00 O B:HOH2003 1.9 51.5 1.0 SG B:CYS185 2.2 60.0 1.0 OE2 B:GLU174 2.3 45.3 1.0 SG B:CYS177 2.5 57.9 1.0 SG B:CYS151 2.5 47.2 1.0 CB B:CYS177 3.0 62.4 1.0 CB B:CYS185 3.3 59.4 1.0 CA B:CYS177 3.4 64.0 1.0 CB B:CYS151 3.5 47.4 1.0 CD B:GLU174 3.5 54.4 1.0 N B:VAL178 4.0 63.5 1.0 C B:CYS177 4.1 64.0 1.0 OE1 B:GLU174 4.2 52.3 1.0 OG B:SER133 4.2 61.5 1.0 N B:CYS151 4.3 50.2 1.0 CA B:CYS185 4.4 59.7 1.0 CG2 B:VAL178 4.4 59.9 1.0 CE3 B:TRP130 4.5 41.2 1.0 O B:GLU176 4.5 62.3 1.0 CB B:SER133 4.5 48.7 1.0 CA B:CYS151 4.5 48.5 1.0 CG B:GLU174 4.5 54.5 1.0 N B:CYS177 4.7 65.7 1.0 N B:GLY179 4.8 66.0 1.0 CZ3 B:TRP130 4.8 47.2 1.0 CA B:GLY136 4.9 51.9 1.0 N B:VAL150 4.9 51.8 1.0

V.V.Patil, K.-H.Park, S.-G.Lee, E.J.Woo. Structural Analysis of the Phenol-Responsive Sensory Domain of the Transcription Activator Poxr Structure V. 624 24 2016.
ISSN: ISSN 0969-2126
PubMed: 27050690
DOI: 10.1016/J.STR.2016.03.006