Zinc in PDB 5b5w: Crystal Structure of MOB1-LATS1 Ntr Domain Complex

All present enzymatic activity of Crystal Structure of MOB1-LATS1 Ntr Domain Complex:
2.7.11.1;

The structure of Crystal Structure of MOB1-LATS1 Ntr Domain Complex, PDB code: 5b5w was solved by S.-Y.Kim, Y.Tachioka, T.Mori, T.Hakoshima, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	28.30 / 2.96
Space group	C 1 2 1
Cell size a, b, c (Å), α, β, γ (°)	78.747, 71.760, 57.855, 90.00, 101.99, 90.00
R / Rfree (%)	23.4 / 27

The binding sites of Zinc atom in the Crystal Structure of MOB1-LATS1 Ntr Domain Complex (pdb code 5b5w). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Crystal Structure of MOB1-LATS1 Ntr Domain Complex, PDB code: 5b5w:

Zinc binding site 1 out of 1 in the Crystal Structure of MOB1-LATS1 Ntr Domain Complex


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure of MOB1-LATS1 Ntr Domain Complex within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn301 b:0.4 occ:1.00 NE2 A:HIS161 2.0 96.6 1.0 NE2 A:HIS166 2.0 0.6 1.0 CB A:CYS79 2.3 0.5 1.0 CE1 A:HIS161 2.3 75.4 1.0 SG A:CYS84 2.3 0.2 1.0 SG A:CYS79 2.5 0.9 1.0 CD2 A:HIS166 2.9 0.9 1.0 CA A:CYS79 3.1 0.2 1.0 CE1 A:HIS166 3.1 0.2 1.0 CD2 A:HIS161 3.4 0.8 1.0 CB A:CYS84 3.4 0.2 1.0 ND1 A:HIS161 3.6 77.5 1.0 N A:CYS79 4.0 0.3 1.0 CG A:HIS166 4.1 0.9 1.0 CG A:HIS161 4.1 96.5 1.0 ND1 A:HIS166 4.1 0.3 1.0 C A:CYS79 4.2 0.3 1.0 CB A:ALA111 4.3 0.9 1.0 CA A:CYS84 4.8 0.6 1.0 O A:CYS79 4.8 0.4 1.0 N A:CYS84 4.9 0.2 1.0 C A:PHE78 4.9 0.2 1.0 N A:THR80 4.9 0.7 1.0 CB A:GLN165 5.0 99.5 1.0 O A:PHE78 5.0 0.3 1.0

S.Y.Kim, Y.Tachioka, T.Mori, T.Hakoshima. Structural Basis For Autoinhibition and Its Relief of MOB1 in the Hippo Pathway Sci Rep V. 6 28488 2016.
ISSN: ESSN 2045-2322
PubMed: 27335147
DOI: 10.1038/SREP28488