Zinc in PDB 4zne: IGG1 Fc-Fcgammari Ecd Complex

The structure of IGG1 Fc-Fcgammari Ecd Complex, PDB code: 4zne was solved by V.Y.Oganesyan, W.F.Dall'acqua, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	86.55 / 2.42
Space group	C 1 2 1
Cell size a, b, c (Å), α, β, γ (°)	134.735, 126.750, 71.844, 90.00, 118.44, 90.00
R / Rfree (%)	20.1 / 25.4

The binding sites of Zinc atom in the IGG1 Fc-Fcgammari Ecd Complex (pdb code 4zne). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 3 binding sites of Zinc where determined in the IGG1 Fc-Fcgammari Ecd Complex, PDB code: 4zne:
Jump to Zinc binding site number: 1; 2; 3;

Zinc binding site 1 out of 3 in the IGG1 Fc-Fcgammari Ecd Complex


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of IGG1 Fc-Fcgammari Ecd Complex within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn310 b:67.0 occ:1.00 OE2 A:GLU261 1.9 33.7 1.0 CD A:GLU261 2.8 32.2 1.0 OE1 A:GLU261 3.0 30.2 1.0 CG A:GLU261 4.2 31.0 1.0 CH2 A:TRP259 4.3 28.6 1.0 CZ3 A:TRP259 4.4 28.9 1.0 CD2 A:LEU270 4.9 41.2 1.0

Zinc binding site 2 out of 3 in the IGG1 Fc-Fcgammari Ecd Complex


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of IGG1 Fc-Fcgammari Ecd Complex within 5.0Å range: probe atom residue distance (Å) B Occ E:Zn509 b:49.2 occ:1.00 ND1 E:HIS433 1.9 31.7 1.0 CE1 E:HIS433 2.8 31.7 1.0 CG E:HIS433 3.0 31.9 1.0 CB E:HIS433 3.5 32.0 1.0 NE2 E:HIS433 3.9 32.7 1.0 CA E:HIS433 4.0 32.1 1.0 CD2 E:HIS433 4.0 33.0 1.0 O E:HOH657 4.3 41.5 1.0 N E:ASN434 5.0 33.0 1.0

Zinc binding site 3 out of 3 in the IGG1 Fc-Fcgammari Ecd Complex


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 3 of IGG1 Fc-Fcgammari Ecd Complex within 5.0Å range: probe atom residue distance (Å) B Occ J:Zn509 b:47.4 occ:1.00 NE2 J:HIS310 1.9 21.2 1.0 NE2 J:HIS435 2.0 28.8 1.0 CE1 J:HIS310 2.8 24.0 1.0 CD2 J:HIS435 2.9 28.3 1.0 CD2 J:HIS310 3.0 23.5 1.0 CE1 J:HIS435 3.1 27.1 1.0 NE2 J:GLN311 3.2 46.5 1.0 ND1 J:HIS310 4.0 24.6 1.0 CG J:HIS310 4.1 23.6 1.0 CG J:HIS435 4.1 28.1 1.0 ND1 J:HIS435 4.2 27.1 1.0 CD1 J:LEU314 4.2 30.5 1.0 CD J:GLN311 4.5 45.9 1.0 CD1 J:ILE253 4.6 33.4 1.0

V.Oganesyan, Y.Mazor, C.Yang, K.E.Cook, R.M.Woods, A.Ferguson, M.A.Bowen, T.Martin, J.Zhu, H.Wu, W.F.Dall'acqua. Structural Insights Into the Interaction of Human IGG1 with Fc Gamma Ri: No Direct Role of Glycans in Binding. Acta Crystallogr.,Sect.D V. 71 2354 2015.
ISSN: ESSN 1399-0047
PubMed: 26527150
DOI: 10.1107/S1399004715018015