Zinc in PDB 4z65: Carboxypeptidase B with Sulphamoil Arginine

All present enzymatic activity of Carboxypeptidase B with Sulphamoil Arginine:
3.4.17.2;

The structure of Carboxypeptidase B with Sulphamoil Arginine, PDB code: 4z65 was solved by V.I.Timofeev, V.K.Akparov, I.P.Kuranova, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	30.00 / 1.25
Space group	P 41 21 2
Cell size a, b, c (Å), α, β, γ (°)	79.380, 79.380, 100.370, 90.00, 90.00, 90.00
R / Rfree (%)	15.9 / 18

The binding sites of Zinc atom in the Carboxypeptidase B with Sulphamoil Arginine (pdb code 4z65). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Carboxypeptidase B with Sulphamoil Arginine, PDB code: 4z65:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Carboxypeptidase B with Sulphamoil Arginine


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Carboxypeptidase B with Sulphamoil Arginine within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn401 b:5.8 occ:1.00 N19 A:0X9402 2.0 6.2 1.0 OE2 A:GLU72 2.1 5.7 1.0 ND1 A:HIS69 2.1 5.8 1.0 ND1 A:HIS197 2.1 5.6 1.0 OE1 A:GLU72 2.4 6.2 1.0 CD A:GLU72 2.6 5.8 1.0 CE1 A:HIS69 3.0 6.2 1.0 CE1 A:HIS197 3.1 6.3 1.0 CG A:HIS197 3.1 5.7 1.0 CG A:HIS69 3.1 5.6 1.0 S18 A:0X9402 3.1 6.2 1.0 O21 A:0X9402 3.2 6.4 1.0 CB A:HIS197 3.4 5.8 1.0 CB A:HIS69 3.5 6.1 1.0 O A:SER198 3.9 6.3 1.0 O A:HOH710 3.9 7.6 1.0 CG A:GLU72 4.1 6.3 1.0 N17 A:0X9402 4.1 6.5 1.0 NE2 A:HIS69 4.2 6.2 1.0 NE2 A:HIS197 4.2 6.2 1.0 CA A:HIS197 4.2 5.6 1.0 O20 A:0X9402 4.2 7.1 1.0 CD2 A:HIS69 4.2 6.2 1.0 CD2 A:HIS197 4.2 6.1 1.0 C13 A:0X9402 4.3 7.4 1.0 N A:SER198 4.4 5.5 1.0 NH1 A:ARG127 4.4 7.7 1.0 O A:HOH516 4.6 9.0 1.0 O16 A:0X9402 4.7 10.1 1.0 C14 A:0X9402 4.7 11.9 1.0 CA A:HIS69 4.8 6.0 1.0 OE1 A:GLU271 4.8 6.8 1.0 CB A:GLU72 4.9 6.6 1.0 N A:HIS69 4.9 6.4 1.0 C A:HIS197 4.9 5.3 1.0 C A:SER198 5.0 5.3 1.0

Zinc binding site 2 out of 2 in the Carboxypeptidase B with Sulphamoil Arginine


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Carboxypeptidase B with Sulphamoil Arginine within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn403 b:9.0 occ:1.00 OE2 A:GLU85 2.0 8.1 1.0 OE1 A:GLU292 2.0 7.3 1.0 O A:HOH514 2.1 8.8 1.0 OE2 A:GLU292 2.2 7.9 1.0 CD A:GLU292 2.4 7.6 1.0 CD A:GLU85 3.0 8.4 1.0 OE1 A:GLU85 3.3 10.9 1.0 NH2 A:ARG84 3.9 9.8 1.0 CG A:GLU292 4.0 8.0 1.0 NE1 A:TRP81 4.3 7.9 1.0 CG A:GLU85 4.4 9.1 1.0 O A:HOH536 4.4 9.0 1.0 O A:HOH763 4.4 19.2 1.0 CB A:GLU292 4.9 7.8 1.0 CZ2 A:TRP81 4.9 9.5 1.0

V.Akparov, N.Sokolenko, V.Timofeev, I.Kuranova. Structure of the Complex of Carboxypeptidase B and N-Sulfamoyl-L-Arginine. Acta Crystallogr.,Sect.F V. 71 1335 2015.
ISSN: ESSN 2053-230X
PubMed: 26457527
DOI: 10.1107/S2053230X15016799