Zinc in PDB 4y8a: Crystal Structure of the N-Terminal Domain of CEACAM6

The structure of Crystal Structure of the N-Terminal Domain of CEACAM6, PDB code: 4y8a was solved by D.A.Bonsor, E.J.Sundberg, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	83.71 / 1.83
Space group	P 63
Cell size a, b, c (Å), α, β, γ (°)	96.660, 96.660, 54.360, 90.00, 90.00, 120.00
R / Rfree (%)	16.7 / 19.5

The binding sites of Zinc atom in the Crystal Structure of the N-Terminal Domain of CEACAM6 (pdb code 4y8a). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 7 binding sites of Zinc where determined in the Crystal Structure of the N-Terminal Domain of CEACAM6, PDB code: 4y8a:
Jump to Zinc binding site number: 1; 2; 3; 4; 5; 6; 7;

Zinc binding site 1 out of 7 in the Crystal Structure of the N-Terminal Domain of CEACAM6


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure of the N-Terminal Domain of CEACAM6 within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn201 b:14.6 occ:0.33 NE2 A:HIS106 2.2 15.6 1.0 O A:HOH327 2.2 14.3 1.0 CE1 A:HIS106 3.1 11.5 1.0 CD2 A:HIS106 3.2 11.9 1.0 ND1 A:HIS106 4.2 11.7 1.0 CG A:HIS106 4.3 12.8 1.0 O A:VAL107 4.3 17.1 1.0 O A:HOH314 4.8 18.5 1.0

Zinc binding site 2 out of 7 in the Crystal Structure of the N-Terminal Domain of CEACAM6


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Crystal Structure of the N-Terminal Domain of CEACAM6 within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn202 b:18.8 occ:1.00 OD1 A:ASP41 2.0 16.5 1.0 O1 A:GOL206 2.2 19.7 1.0 O B:HOH324 2.2 17.1 1.0 O2 A:GOL206 2.2 20.8 1.0 CG A:ASP41 2.9 21.9 1.0 C1 A:GOL206 3.1 23.5 1.0 C2 A:GOL206 3.1 22.3 1.0 OD2 A:ASP41 3.2 18.7 1.0 OE2 B:GLU100 3.6 21.8 1.0 ND2 A:ASN43 3.9 18.2 1.0 NH1 A:ARG39 4.2 19.9 1.0 CB A:ASP41 4.2 17.2 1.0 NH2 A:ARG39 4.2 23.1 1.0 O A:HOH360 4.3 23.2 1.0 C3 A:GOL206 4.4 25.4 1.0 CZ A:ARG39 4.7 21.8 1.0 CB A:ASN43 4.7 18.2 1.0 CG A:ASN43 4.8 20.9 1.0 CA A:ASP41 4.8 13.1 1.0 CD B:GLU100 4.8 24.1 1.0 N A:GLY42 5.0 14.6 1.0 N A:ASN43 5.0 15.7 1.0

Zinc binding site 3 out of 7 in the Crystal Structure of the N-Terminal Domain of CEACAM6


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 3 of Crystal Structure of the N-Terminal Domain of CEACAM6 within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn203 b:49.0 occ:0.33 O A:HOH363 2.3 38.4 1.0 O A:HOH354 4.2 41.1 1.0 O A:TYR108 4.4 24.2 1.0 OE1 A:GLN81 4.5 44.3 1.0 NE2 A:GLN81 5.0 65.1 1.0

Zinc binding site 4 out of 7 in the Crystal Structure of the N-Terminal Domain of CEACAM6


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 4 of Crystal Structure of the N-Terminal Domain of CEACAM6 within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn204 b:44.8 occ:1.00 O A:HOH356 2.1 30.1 1.0 O A:HOH354 2.2 41.1 1.0 O A:TYR108 2.3 24.2 1.0 OE2 A:GLU14 2.4 45.3 1.0 OXT A:TYR108 2.9 17.2 1.0 C A:TYR108 3.0 23.0 1.0 CD A:GLU14 3.1 45.1 1.0 CG A:GLU14 3.2 38.5 1.0 NE2 A:GLN81 3.4 65.1 1.0 O A:HOH363 4.2 38.4 1.0 OE1 A:GLU14 4.2 28.1 1.0 CD1 A:TYR108 4.4 22.0 1.0 CA A:TYR108 4.4 16.5 1.0 CB A:GLU14 4.4 27.3 1.0 O A:HOH308 4.5 28.8 1.0 CD A:GLN81 4.7 38.3 1.0 N A:GLU14 4.8 16.5 1.0 O A:HOH335 5.0 40.2 1.0 CB A:TYR108 5.0 17.4 1.0

Zinc binding site 5 out of 7 in the Crystal Structure of the N-Terminal Domain of CEACAM6


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 5 of Crystal Structure of the N-Terminal Domain of CEACAM6 within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn205 b:37.8 occ:1.00 O A:HOH306 2.1 22.9 1.0 O A:ALA1 2.2 53.8 1.0 O A:HOH362 2.2 33.8 1.0 O A:HOH307 2.3 29.1 1.0 O A:HOH359 2.6 30.9 1.0 N A:ALA1 2.8 51.6 1.0 C A:ALA1 3.2 46.5 1.0 CA A:ALA1 3.5 54.1 1.0 OE1 A:GLU99 4.0 24.5 1.0 O A:ASN24 4.0 21.9 1.0 OE2 A:GLU99 4.2 27.7 1.0 CB A:ALA1 4.2 46.5 1.0 N A:LYS2 4.4 39.6 1.0 O A:HOH337 4.5 33.5 1.0 CD A:GLU99 4.5 25.9 1.0 CA A:PRO26 4.5 21.0 1.0 O A:HOH331 4.7 27.3 1.0 N A:PRO26 4.8 20.0 1.0 CB A:PRO26 4.8 20.1 1.0 CB A:ASN24 4.8 21.2 1.0 C A:ASN24 4.9 22.2 1.0 CA A:LYS2 5.0 24.8 1.0 O A:LEU25 5.0 20.6 1.0 C A:LEU25 5.0 22.4 1.0

Zinc binding site 6 out of 7 in the Crystal Structure of the N-Terminal Domain of CEACAM6


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 6 of Crystal Structure of the N-Terminal Domain of CEACAM6 within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn207 b:22.4 occ:1.00 OE1 B:GLU6 1.8 30.5 1.0 O B:HOH346 2.1 15.0 1.0 NE2 B:HIS23 2.1 19.1 1.0 CD B:GLU6 2.6 37.7 1.0 OE2 B:GLU6 2.9 40.0 1.0 CD2 B:HIS23 3.1 26.2 1.0 CE1 B:HIS23 3.1 21.2 1.0 CG B:GLU6 4.0 32.7 1.0 ND1 B:HIS23 4.2 20.1 1.0 CG B:HIS23 4.2 19.1 1.0 CD1 B:LEU21 4.2 55.3 1.0 CB B:GLU6 4.4 23.4 1.0

Zinc binding site 7 out of 7 in the Crystal Structure of the N-Terminal Domain of CEACAM6


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 7 of Crystal Structure of the N-Terminal Domain of CEACAM6 within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn201 b:40.0 occ:1.00 O B:HOH305 2.1 24.0 1.0 O B:HOH352 2.2 33.0 1.0 O B:HOH302 2.3 30.3 1.0 O B:HOH350 2.8 37.3 1.0 O B:ALA1 2.8 70.2 1.0 C B:ALA1 4.0 66.0 1.0 OE1 B:GLU99 4.1 24.6 1.0 O B:ASN24 4.1 20.6 1.0 OE2 B:GLU99 4.2 23.3 1.0 CB B:ALA1 4.3 67.1 1.0 O B:HOH341 4.4 34.0 1.0 CD B:GLU99 4.5 35.8 1.0 CA B:PRO26 4.6 24.7 1.0 O B:HOH326 4.7 30.3 1.0 N B:PRO26 4.8 21.1 1.0 CB B:PRO26 4.8 21.2 1.0 CA B:ALA1 4.8 70.5 1.0 C B:ASN24 5.0 20.9 1.0 N B:LYS2 5.0 43.7 1.0

D.A.Bonsor, S.Gunther, R.Beadenkopf, D.Beckett, E.J.Sundberg. Diverse Oligomeric States of Ceacam Igv Domains. Proc.Natl.Acad.Sci.Usa V. 112 13561 2015.
ISSN: ESSN 1091-6490
PubMed: 26483485
DOI: 10.1073/PNAS.1509511112