Zinc in PDB 4wwx: Crystal Structure of the Core RAG1/2 Recombinase

The structure of Crystal Structure of the Core RAG1/2 Recombinase, PDB code: 4wwx was solved by M.S.Kim, M.Lapkouski, W.Yang, M.Gellert, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	43.74 / 3.20
Space group	C 2 2 21
Cell size a, b, c (Å), α, β, γ (°)	168.760, 180.050, 200.190, 90.00, 90.00, 90.00
R / Rfree (%)	20.6 / 25.9

The binding sites of Zinc atom in the Crystal Structure of the Core RAG1/2 Recombinase (pdb code 4wwx). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Crystal Structure of the Core RAG1/2 Recombinase, PDB code: 4wwx:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Crystal Structure of the Core RAG1/2 Recombinase


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure of the Core RAG1/2 Recombinase within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn1101 b:83.9 occ:1.00 NE2 B:HIS937 2.1 74.5 1.0 NE2 B:HIS942 2.2 69.8 1.0 SG B:CYS727 2.2 70.3 1.0 SG B:CYS730 2.3 71.3 1.0 CD2 B:HIS942 2.7 73.4 1.0 CE1 B:HIS937 2.9 79.3 1.0 CB B:CYS727 3.1 71.4 1.0 CD2 B:HIS937 3.1 76.0 1.0 CE1 B:HIS942 3.4 79.8 1.0 CB B:CYS730 3.7 76.1 1.0 ND1 B:HIS937 4.0 80.3 1.0 CG B:HIS942 4.0 76.7 1.0 N B:CYS730 4.1 76.0 1.0 CG B:HIS937 4.1 81.8 1.0 CG2 B:THR732 4.2 81.2 1.0 ND1 B:HIS942 4.3 75.2 1.0 CA B:CYS730 4.4 75.7 1.0 CA B:CYS727 4.5 74.2 1.0 CB B:HIS744 4.6 73.9 1.0 CB B:LEU729 4.7 77.7 1.0 C B:LEU729 4.8 81.2 1.0 CD1 B:LEU729 4.9 73.5 1.0 CB B:ALA941 4.9 74.2 1.0 C B:CYS730 5.0 79.5 1.0

Zinc binding site 2 out of 2 in the Crystal Structure of the Core RAG1/2 Recombinase


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Crystal Structure of the Core RAG1/2 Recombinase within 5.0Å range: probe atom residue distance (Å) B Occ E:Zn1101 b:86.1 occ:1.00 NE2 E:HIS942 1.9 70.0 1.0 NE2 E:HIS937 2.0 70.0 1.0 SG E:CYS730 2.1 63.3 1.0 SG E:CYS727 2.2 75.8 1.0 CD2 E:HIS942 2.8 77.2 1.0 CE1 E:HIS937 2.8 74.9 1.0 CE1 E:HIS942 3.0 76.3 1.0 CD2 E:HIS937 3.0 85.6 1.0 CB E:CYS727 3.2 71.6 1.0 CB E:CYS730 3.4 70.1 1.0 N E:CYS730 3.8 73.0 1.0 ND1 E:HIS937 3.9 78.6 1.0 CG E:HIS942 3.9 77.7 1.0 ND1 E:HIS942 4.0 78.6 1.0 CG E:HIS937 4.1 83.7 1.0 CA E:CYS730 4.1 73.3 1.0 CG2 E:THR732 4.2 83.4 1.0 C E:LEU729 4.5 80.8 1.0 CB E:LEU729 4.5 80.9 1.0 CA E:CYS727 4.7 75.7 1.0 CB E:HIS744 4.7 69.0 1.0 C E:CYS730 4.7 76.6 1.0 O E:CYS730 4.8 77.1 1.0 CA E:LEU729 4.9 82.5 1.0 N E:LEU729 4.9 78.0 1.0

M.S.Kim, M.Lapkouski, W.Yang, M.Gellert. Crystal Structure of the V(D)J Recombinase RAG1-RAG2 Nature 2015.
ISSN: ESSN 1476-4687