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Zinc in PDB 4w6e: Human Tankyrase 1 with Small Molecule InhibitorEnzymatic activity of Human Tankyrase 1 with Small Molecule Inhibitor
All present enzymatic activity of Human Tankyrase 1 with Small Molecule Inhibitor:
2.4.2.30; Protein crystallography data
The structure of Human Tankyrase 1 with Small Molecule Inhibitor, PDB code: 4w6e
was solved by
S.L.Kazmirski,
J.Johannes,
P.A.Boriack-Sjodin,
T.Howard,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Zinc Binding Sites:
The binding sites of Zinc atom in the Human Tankyrase 1 with Small Molecule Inhibitor
(pdb code 4w6e). This binding sites where shown within
5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Human Tankyrase 1 with Small Molecule Inhibitor, PDB code: 4w6e: Zinc binding site 1 out of 1 in 4w6eGo back to Zinc Binding Sites List in 4w6e
Zinc binding site 1 out
of 1 in the Human Tankyrase 1 with Small Molecule Inhibitor
Mono view Stereo pair view
Reference:
J.W.Johannes,
L.Almeida,
B.Barlaam,
P.A.Boriack-Sjodin,
R.Casella,
R.A.Croft,
A.P.Dishington,
L.Gingipalli,
C.Gu,
J.L.Hawkins,
J.L.Holmes,
T.Howard,
J.Huang,
S.Ioannidis,
S.Kazmirski,
M.L.Lamb,
T.M.Mcguire,
J.E.Moore,
D.Ogg,
A.Patel,
K.G.Pike,
T.Pontz,
G.R.Robb,
N.Su,
H.Wang,
X.Wu,
H.J.Zhang,
Y.Zhang,
X.Zheng,
T.Wang.
Pyrimidinone Nicotinamide Mimetics As Selective Tankyrase and Wnt Pathway Inhibitors Suitable For in Vivo Pharmacology. Acs Med.Chem.Lett. V. 6 254 2015.
Page generated: Wed Dec 16 05:50:36 2020
ISSN: ISSN 1948-5875 PubMed: 25815142 DOI: 10.1021/ML5003663 |
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