Zinc in PDB 4rqm: Crystal Structure of the Semet BICC1 Sam Domain R924E Mutant

The structure of Crystal Structure of the Semet BICC1 Sam Domain R924E Mutant, PDB code: 4rqm was solved by C.N.Leettola, D.Cascio, J.U.Bowie, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	47.60 / 1.75
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	46.810, 64.430, 70.640, 90.00, 90.00, 90.00
R / Rfree (%)	23 / 26.7

The binding sites of Zinc atom in the Crystal Structure of the Semet BICC1 Sam Domain R924E Mutant (pdb code 4rqm). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Crystal Structure of the Semet BICC1 Sam Domain R924E Mutant, PDB code: 4rqm:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Crystal Structure of the Semet BICC1 Sam Domain R924E Mutant


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure of the Semet BICC1 Sam Domain R924E Mutant within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn1001 b:30.8 occ:0.50 ZN B:ZN1001 0.0 30.8 0.5 OD1 B:ASP911 2.1 28.6 1.0 OE2 A:GLU924 2.2 34.1 1.0 ZN B:ZN1001 2.2 25.5 0.5 CD A:GLU924 2.8 38.4 1.0 OE1 A:GLU924 2.9 42.6 1.0 CG B:ASP911 2.9 28.7 1.0 OD2 B:ASP911 3.2 29.0 1.0 O B:HOH1112 4.0 54.9 1.0 CG A:GLU924 4.3 27.4 1.0 O B:HOH1103 4.3 41.8 1.0 OG1 B:THR908 4.4 32.6 1.0 CB B:ASP911 4.4 26.4 1.0 CA B:ASP911 4.8 26.7 1.0 OE1 B:GLU914 4.9 40.8 1.0 N B:ASP911 4.9 24.9 1.0

Zinc binding site 2 out of 2 in the Crystal Structure of the Semet BICC1 Sam Domain R924E Mutant


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Crystal Structure of the Semet BICC1 Sam Domain R924E Mutant within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn1001 b:25.5 occ:0.50 ZN B:ZN1001 0.0 25.5 0.5 OE2 A:GLU924 1.8 34.1 1.0 O B:HOH1112 1.8 54.9 1.0 OD2 B:ASP911 1.9 29.0 1.0 ZN B:ZN1001 2.2 30.8 0.5 CG B:ASP911 2.6 28.7 1.0 OD1 B:ASP911 2.7 28.6 1.0 CD A:GLU924 3.0 38.4 1.0 OE1 A:GLU924 3.7 42.6 1.0 CG A:GLU924 4.1 27.4 1.0 CB B:ASP911 4.1 26.4 1.0 CZ A:PHE920 4.1 25.9 1.0 OG1 B:THR908 4.3 32.6 1.0 O B:THR906 4.4 29.2 1.0 N B:THR908 4.6 25.5 1.0 CG2 B:THR908 4.6 28.5 1.0 CE1 A:PHE920 4.8 26.1 1.0 CA B:LEU907 4.9 26.0 1.0

B.Rothe, C.N.Leettola, L.Leal-Esteban, D.Cascio, S.Fortier, M.Isenschmid, J.U.Bowie, D.B.Constam. Crystal Structure of BICC1 Sam Polymer and Mapping of Interactions Between the Ciliopathy-Associated Proteins BICC1, ANKS3, and ANKS6. Structure V. 26 209 2018.
ISSN: ISSN 0969-2126
PubMed: 29290488
DOI: 10.1016/J.STR.2017.12.002