Zinc in PDB 4rp7: Structure of the Amyloid-Forming Segment Tiitle From P53 (Residues 253-258)

The structure of Structure of the Amyloid-Forming Segment Tiitle From P53 (Residues 253-258), PDB code: 4rp7 was solved by A.B.Soriaga, A.Soragni, D.Eisenberg, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	21.49 / 1.58
Space group	C 1 2 1
Cell size a, b, c (Å), α, β, γ (°)	43.018, 4.849, 19.774, 90.00, 92.12, 90.00
R / Rfree (%)	16.4 / 19.3

The binding sites of Zinc atom in the Structure of the Amyloid-Forming Segment Tiitle From P53 (Residues 253-258) (pdb code 4rp7). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Structure of the Amyloid-Forming Segment Tiitle From P53 (Residues 253-258), PDB code: 4rp7:

Zinc binding site 1 out of 1 in the Structure of the Amyloid-Forming Segment Tiitle From P53 (Residues 253-258)


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Structure of the Amyloid-Forming Segment Tiitle From P53 (Residues 253-258) within 5.0Å range: probe atom residue distance (Å) B Occ Z:Zn101 b:6.4 occ:1.00 N Z:THR1 2.1 5.9 1.0 CA Z:THR1 3.0 4.9 1.0 C Z:THR1 3.5 4.7 1.0 O Z:HOH201 3.8 14.9 1.0 O Z:THR1 3.9 4.2 1.0 N Z:ILE2 4.1 3.6 1.0 CB Z:THR1 4.4 10.7 1.0 CG1 Z:ILE2 4.4 5.3 1.0 OG1 Z:THR1 4.6 12.9 1.0

A.Soragni, D.M.Janzen, L.M.Johnson, A.G.Lindgren, A.Thai-Quynh Nguyen, E.Tiourin, A.B.Soriaga, J.Lu, L.Jiang, K.F.Faull, M.Pellegrini, S.Memarzadeh, D.S.Eisenberg. A Designed Inhibitor of P53 Aggregation Rescues P53 Tumor Suppression in Ovarian Carcinomas. Cancer Cell V. 29 90 2016.
ISSN: ISSN 1535-6108
PubMed: 26748848
DOI: 10.1016/J.CCELL.2015.12.002