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Atomistry » Zinc » PDB 4qqr-4r5t » 4qsb » |
Zinc in PDB 4qsb: Crystal Structure of Human Carbonic Anhydrase Isozyme II with 3-{[(4- Methyl-6-Oxo-1,6-Dihydropyrimidin-2-Yl)Thio]Acetyl}BenzenesulfonamideEnzymatic activity of Crystal Structure of Human Carbonic Anhydrase Isozyme II with 3-{[(4- Methyl-6-Oxo-1,6-Dihydropyrimidin-2-Yl)Thio]Acetyl}Benzenesulfonamide
All present enzymatic activity of Crystal Structure of Human Carbonic Anhydrase Isozyme II with 3-{[(4- Methyl-6-Oxo-1,6-Dihydropyrimidin-2-Yl)Thio]Acetyl}Benzenesulfonamide:
4.2.1.1; Protein crystallography data
The structure of Crystal Structure of Human Carbonic Anhydrase Isozyme II with 3-{[(4- Methyl-6-Oxo-1,6-Dihydropyrimidin-2-Yl)Thio]Acetyl}Benzenesulfonamide, PDB code: 4qsb
was solved by
A.Smirnov,
E.Manakova,
S.Grazulis,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Zinc Binding Sites:
The binding sites of Zinc atom in the Crystal Structure of Human Carbonic Anhydrase Isozyme II with 3-{[(4- Methyl-6-Oxo-1,6-Dihydropyrimidin-2-Yl)Thio]Acetyl}Benzenesulfonamide
(pdb code 4qsb). This binding sites where shown within
5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Crystal Structure of Human Carbonic Anhydrase Isozyme II with 3-{[(4- Methyl-6-Oxo-1,6-Dihydropyrimidin-2-Yl)Thio]Acetyl}Benzenesulfonamide, PDB code: 4qsb: Zinc binding site 1 out of 1 in 4qsbGo back to Zinc Binding Sites List in 4qsb
Zinc binding site 1 out
of 1 in the Crystal Structure of Human Carbonic Anhydrase Isozyme II with 3-{[(4- Methyl-6-Oxo-1,6-Dihydropyrimidin-2-Yl)Thio]Acetyl}Benzenesulfonamide
Mono view Stereo pair view
Reference:
M.Kisonaite,
A.Zubriene,
E.Capkauskaite,
A.Smirnov,
J.Smirnoviene,
V.Kairys,
V.Michailoviene,
E.Manakova,
S.Grazulis,
D.Matulis.
Intrinsic Thermodynamics and Structure Correlation of Benzenesulfonamides with A Pyrimidine Moiety Binding to Carbonic Anhydrases I, II, VII, XII, and XIII Plos One V. 9 14106 2014.
Page generated: Sun Oct 27 06:44:28 2024
ISSN: ESSN 1932-6203 PubMed: 25493428 DOI: 10.1371/JOURNAL.PONE.0114106 |
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