Zinc in PDB 4mth: Crystal Structure of Mature Human Regiiialpha

The structure of Crystal Structure of Mature Human Regiiialpha, PDB code: 4mth was solved by M.G.Derebe, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	26.13 / 1.47
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	30.762, 49.528, 92.152, 90.00, 90.00, 90.00
R / Rfree (%)	18.5 / 21

The binding sites of Zinc atom in the Crystal Structure of Mature Human Regiiialpha (pdb code 4mth). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 3 binding sites of Zinc where determined in the Crystal Structure of Mature Human Regiiialpha, PDB code: 4mth:
Jump to Zinc binding site number: 1; 2; 3;

Zinc binding site 1 out of 3 in the Crystal Structure of Mature Human Regiiialpha


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure of Mature Human Regiiialpha within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn201 b:14.1 occ:1.00 OE1 A:GLU121 2.0 15.1 1.0 NE2 A:HIS107 2.0 12.7 1.0 O A:HOH335 2.2 8.0 1.0 CE1 A:HIS107 2.9 13.7 1.0 CD A:GLU121 3.0 16.2 1.0 CD2 A:HIS107 3.2 13.5 1.0 CG A:GLU121 3.4 12.6 1.0 ND1 A:HIS107 4.0 13.7 1.0 CG A:PRO109 4.1 17.4 1.0 OE2 A:GLU121 4.1 17.6 1.0 CG A:HIS107 4.2 12.8 1.0 O A:HOH395 4.3 26.4 1.0 CD A:PRO109 4.4 14.1 1.0 CB A:PRO109 4.5 16.3 1.0 CB A:GLU121 4.9 11.2 1.0

Zinc binding site 2 out of 3 in the Crystal Structure of Mature Human Regiiialpha


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Crystal Structure of Mature Human Regiiialpha within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn202 b:26.9 occ:1.00 O A:HOH444 2.1 28.1 1.0 O A:HOH354 2.1 21.2 1.0 O A:HOH473 2.3 32.9 1.0 NE2 A:HIS50 2.3 21.5 1.0 O A:HOH413 2.4 26.7 1.0 O A:HOH447 2.4 32.4 1.0 O A:HOH318 2.5 39.8 1.0 CD2 A:HIS50 3.2 18.4 1.0 CE1 A:HIS50 3.4 21.0 1.0 O A:HOH393 3.8 29.3 1.0 CG2 A:THR174 3.9 18.2 1.0 O A:HOH428 4.0 30.2 1.0 O A:HOH385 4.1 31.3 1.0 O A:HOH344 4.3 18.7 1.0 CG A:HIS50 4.4 13.7 1.0 O A:SER73 4.4 14.8 1.0 ND1 A:HIS50 4.5 21.1 1.0 CB A:SER73 4.6 18.9 1.0 O A:HOH352 4.6 20.1 1.0

Zinc binding site 3 out of 3 in the Crystal Structure of Mature Human Regiiialpha


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 3 of Crystal Structure of Mature Human Regiiialpha within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn203 b:28.4 occ:1.00 NE2 A:HIS145 2.1 18.1 1.0 O A:HOH465 2.3 31.6 1.0 O A:HOH469 2.3 32.1 1.0 CE1 A:HIS145 3.0 24.7 1.0 CD2 A:HIS145 3.1 23.9 1.0 O A:PRO143 3.9 19.2 1.0 O A:GLN111 4.1 30.2 1.0 OG A:SER142 4.1 32.9 1.0 ND1 A:HIS145 4.2 20.2 1.0 CG A:HIS145 4.2 18.7 1.0 C A:GLN111 4.9 29.8 1.0 O A:HOH371 4.9 29.6 1.0

S.Mukherjee, H.Zheng, M.G.Derebe, K.M.Callenberg, C.L.Partch, D.Rollins, D.C.Propheter, J.Rizo, M.Grabe, Q.X.Jiang, L.V.Hooper. Antibacterial Membrane Attack By A Pore-Forming Intestinal C-Type Lectin. Nature V. 505 103 2013.
ISSN: ISSN 0028-0836
PubMed: 24256734
DOI: 10.1038/NATURE12729