Zinc in PDB 4mqy: Crystal Structure of the Escherichia Coli Lpxc/Lpc-138 Complex

The structure of Crystal Structure of the Escherichia Coli Lpxc/Lpc-138 Complex, PDB code: 4mqy was solved by C.-J.Lee, J.Najeeb, P.Zhou, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	29.42 / 2.00
Space group	P 61
Cell size a, b, c (Å), α, β, γ (°)	107.515, 107.515, 53.603, 90.00, 90.00, 120.00
R / Rfree (%)	18.2 / 22.5

The binding sites of Zinc atom in the Crystal Structure of the Escherichia Coli Lpxc/Lpc-138 Complex (pdb code 4mqy). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Crystal Structure of the Escherichia Coli Lpxc/Lpc-138 Complex, PDB code: 4mqy:

Zinc binding site 1 out of 1 in the Crystal Structure of the Escherichia Coli Lpxc/Lpc-138 Complex


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure of the Escherichia Coli Lpxc/Lpc-138 Complex within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn401 b:31.9 occ:1.00 O04 A:2CW402 2.0 48.2 1.0 NE2 A:HIS79 2.0 26.3 1.0 NE2 A:HIS238 2.0 29.2 1.0 OD1 A:ASP242 2.1 36.3 1.0 O01 A:2CW402 2.4 44.8 1.0 OD2 A:ASP242 2.4 39.8 1.0 CG A:ASP242 2.6 37.8 1.0 N03 A:2CW402 2.9 39.2 1.0 CE1 A:HIS79 2.9 28.7 1.0 C02 A:2CW402 2.9 43.3 1.0 CE1 A:HIS238 3.0 29.4 1.0 CD2 A:HIS79 3.0 26.8 1.0 CD2 A:HIS238 3.1 31.1 1.0 OG1 A:THR191 4.0 30.9 1.0 ND1 A:HIS79 4.1 28.3 1.0 ND1 A:HIS238 4.1 25.8 1.0 CG A:HIS79 4.1 29.2 1.0 CB A:THR191 4.2 30.3 1.0 CG A:HIS238 4.2 26.8 1.0 CB A:ASP242 4.2 33.9 1.0 C05 A:2CW402 4.4 50.1 1.0 OE2 A:GLU78 4.5 64.7 1.0 NE2 A:HIS265 4.6 38.8 1.0 O27 A:2CW402 4.7 55.2 1.0 CG A:GLU78 4.7 52.5 1.0 CA A:THR191 4.8 24.1 1.0 C28 A:2CW402 4.8 49.1 1.0 O A:HIS238 4.8 32.9 1.0 C26 A:2CW402 4.9 50.8 1.0 CE1 A:HIS265 4.9 39.8 1.0 CA A:ASP242 5.0 32.0 1.0

C.J.Lee, X.Liang, R.Gopalaswamy, J.Najeeb, E.D.Ark, E.J.Toone, P.Zhou. Structural Basis of the Promiscuous Inhibitor Susceptibility of Escherichia Coli Lpxc. Acs Chem.Biol. V. 9 237 2014.
ISSN: ISSN 1554-8929
PubMed: 24117400
DOI: 10.1021/CB400067G