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Atomistry » Zinc » PDB 4lmg-4m2v » 4lnb » |
Zinc in PDB 4lnb: Aspergillus Fumigatus Protein Farnesyltransferase Ternary Complex with Farnesyldiphosphate and Ethylenediamine Scaffold Inhibitor 5Enzymatic activity of Aspergillus Fumigatus Protein Farnesyltransferase Ternary Complex with Farnesyldiphosphate and Ethylenediamine Scaffold Inhibitor 5
All present enzymatic activity of Aspergillus Fumigatus Protein Farnesyltransferase Ternary Complex with Farnesyldiphosphate and Ethylenediamine Scaffold Inhibitor 5:
2.5.1.58; Protein crystallography data
The structure of Aspergillus Fumigatus Protein Farnesyltransferase Ternary Complex with Farnesyldiphosphate and Ethylenediamine Scaffold Inhibitor 5, PDB code: 4lnb
was solved by
M.F.Mabanglo,
M.A.Hast,
L.S.Beese,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Zinc Binding Sites:
The binding sites of Zinc atom in the Aspergillus Fumigatus Protein Farnesyltransferase Ternary Complex with Farnesyldiphosphate and Ethylenediamine Scaffold Inhibitor 5
(pdb code 4lnb). This binding sites where shown within
5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Aspergillus Fumigatus Protein Farnesyltransferase Ternary Complex with Farnesyldiphosphate and Ethylenediamine Scaffold Inhibitor 5, PDB code: 4lnb: Zinc binding site 1 out of 1 in 4lnbGo back to Zinc Binding Sites List in 4lnb
Zinc binding site 1 out
of 1 in the Aspergillus Fumigatus Protein Farnesyltransferase Ternary Complex with Farnesyldiphosphate and Ethylenediamine Scaffold Inhibitor 5
Mono view Stereo pair view
Reference:
M.F.Mabanglo,
M.A.Hast,
N.B.Lubock,
H.W.Hellinga,
L.S.Beese.
Crystal Structures of the Fungal Pathogen Aspergillus Fumigatus Protein Farnesyltransferase Complexed with Substrates and Inhibitors Reveal Features For Antifungal Drug Design. Protein Sci. V. 23 289 2014.
Page generated: Wed Dec 16 05:33:32 2020
ISSN: ISSN 0961-8368 PubMed: 24347326 DOI: 10.1002/PRO.2411 |
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