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Zinc in PDB 4lik: Crystal Structure of the Catalytic Subunit of Human Primase

Protein crystallography data

The structure of Crystal Structure of the Catalytic Subunit of Human Primase, PDB code: 4lik was solved by S.Vaithiyalingam, B.F.Eichman, W.J.Chazin, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 30.40 / 1.70
Space group C 1 2 1
Cell size a, b, c (Å), α, β, γ (°) 101.812, 71.916, 84.797, 90.00, 122.04, 90.00
R / Rfree (%) 17.5 / 19.8

Zinc Binding Sites:

The binding sites of Zinc atom in the Crystal Structure of the Catalytic Subunit of Human Primase (pdb code 4lik). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Crystal Structure of the Catalytic Subunit of Human Primase, PDB code: 4lik:

Zinc binding site 1 out of 1 in 4lik

Go back to Zinc Binding Sites List in 4lik
Zinc binding site 1 out of 1 in the Crystal Structure of the Catalytic Subunit of Human Primase


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure of the Catalytic Subunit of Human Primase within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Zn501

b:38.8
occ:1.00
SG A:CYS128 2.0 36.4 1.0
SG A:CYS122 2.3 41.7 1.0
SG A:CYS121 2.3 37.9 1.0
SG A:CYS131 2.4 32.6 1.0
N A:CYS128 3.2 34.4 1.0
CB A:CYS128 3.2 47.2 1.0
CB A:CYS131 3.3 31.5 1.0
CB A:CYS122 3.4 52.6 1.0
CB A:CYS121 3.5 53.7 1.0
CA A:CYS128 3.7 37.4 1.0
N A:CYS131 3.8 35.9 1.0
N A:CYS122 3.9 51.9 1.0
C A:CYS121 3.9 50.9 1.0
C A:ILE127 4.0 34.8 1.0
NH1 A:ARG119 4.1 46.6 1.0
CA A:CYS131 4.1 29.9 1.0
O A:CYS128 4.2 29.7 1.0
CA A:CYS122 4.2 61.4 1.0
C A:CYS128 4.2 37.9 1.0
O A:CYS121 4.3 61.8 1.0
CA A:CYS121 4.3 50.5 1.0
CA A:ILE127 4.3 33.5 1.0
CB A:LYS130 4.7 44.5 1.0
O A:ILE127 4.8 37.5 1.0
C A:LYS130 4.8 47.4 1.0
N A:LYS130 5.0 33.4 1.0
N A:CYS121 5.0 42.9 1.0

Reference:

S.Vaithiyalingam, D.R.Arnett, A.Aggarwal, B.F.Eichman, E.Fanning, W.J.Chazin. Insights Into Eukaryotic Primer Synthesis From Structures of the P48 Subunit of Human Dna Primase. J.Mol.Biol. V. 426 558 2014.
ISSN: ISSN 0022-2836
PubMed: 24239947
DOI: 10.1016/J.JMB.2013.11.007
Page generated: Sun Oct 27 01:52:26 2024

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