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Atomistry » Zinc » PDB 4hk7-4hwp » 4hlm | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Zinc » PDB 4hk7-4hwp » 4hlm » |
Zinc in PDB 4hlm: Crystal Structure of Tankyrase 2 in Complex with 3',4'- DihydroxyflavoneEnzymatic activity of Crystal Structure of Tankyrase 2 in Complex with 3',4'- Dihydroxyflavone
All present enzymatic activity of Crystal Structure of Tankyrase 2 in Complex with 3',4'- Dihydroxyflavone:
2.4.2.30; Protein crystallography data
The structure of Crystal Structure of Tankyrase 2 in Complex with 3',4'- Dihydroxyflavone, PDB code: 4hlm
was solved by
M.Narwal,
T.Haikarainen,
L.Lehtio,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Zinc Binding Sites:
The binding sites of Zinc atom in the Crystal Structure of Tankyrase 2 in Complex with 3',4'- Dihydroxyflavone
(pdb code 4hlm). This binding sites where shown within
5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Crystal Structure of Tankyrase 2 in Complex with 3',4'- Dihydroxyflavone, PDB code: 4hlm: Jump to Zinc binding site number: 1; 2; Zinc binding site 1 out of 2 in 4hlmGo back to Zinc Binding Sites List in 4hlm
Zinc binding site 1 out
of 2 in the Crystal Structure of Tankyrase 2 in Complex with 3',4'- Dihydroxyflavone
Mono view Stereo pair view
Zinc binding site 2 out of 2 in 4hlmGo back to Zinc Binding Sites List in 4hlm
Zinc binding site 2 out
of 2 in the Crystal Structure of Tankyrase 2 in Complex with 3',4'- Dihydroxyflavone
Mono view Stereo pair view
Reference:
M.Narwal,
T.Haikarainen,
A.Fallarero,
P.M.Vuorela,
L.Lehtio.
Screening and Structural Analysis of Flavones Inhibiting Tankyrases. J.Med.Chem. V. 56 3507 2013.
Page generated: Sun Oct 27 00:11:23 2024
ISSN: ISSN 0022-2623 PubMed: 23574272 DOI: 10.1021/JM3018783 |
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