Zinc in PDB 4hc9: Dna Binding By Gata Transcription Factor-Complex 3

The structure of Dna Binding By Gata Transcription Factor-Complex 3, PDB code: 4hc9 was solved by Y.Chen, D.L.Bates, R.Dey, L.Chen, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	50.00 / 1.60
Space group	C 1 2 1
Cell size a, b, c (Å), α, β, γ (°)	126.118, 30.352, 72.475, 90.00, 98.59, 90.00
R / Rfree (%)	18.1 / 21.6

The binding sites of Zinc atom in the Dna Binding By Gata Transcription Factor-Complex 3 (pdb code 4hc9). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Dna Binding By Gata Transcription Factor-Complex 3, PDB code: 4hc9:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Dna Binding By Gata Transcription Factor-Complex 3


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Dna Binding By Gata Transcription Factor-Complex 3 within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn401 b:13.9 occ:1.00 SG A:CYS342 2.3 12.7 1.0 SG A:CYS339 2.3 13.1 1.0 SG A:CYS321 2.3 14.0 1.0 SG A:CYS318 2.4 13.7 1.0 CB A:CYS342 3.2 14.6 1.0 CB A:CYS321 3.3 12.3 1.0 CB A:CYS318 3.3 11.5 1.0 CB A:CYS339 3.5 12.5 1.0 N A:CYS321 3.8 12.9 1.0 N A:CYS339 4.0 11.8 1.0 CA A:CYS321 4.1 13.6 1.0 CG2 A:THR323 4.1 12.4 1.0 N A:CYS342 4.2 13.0 1.0 CA A:CYS339 4.3 12.9 1.0 CA A:CYS342 4.3 13.0 1.0 O A:HOH524 4.4 31.0 1.0 NH1 A:ARG353 4.6 21.1 1.0 CB A:ASN320 4.7 13.7 1.0 C A:ASN320 4.7 14.0 1.0 CA A:CYS318 4.7 11.9 1.0 C A:CYS321 4.8 13.1 1.0 C A:CYS339 4.9 12.5 1.0 N A:GLN322 4.9 12.9 1.0 O A:CYS339 4.9 13.2 1.0

Zinc binding site 2 out of 2 in the Dna Binding By Gata Transcription Factor-Complex 3


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Dna Binding By Gata Transcription Factor-Complex 3 within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn402 b:26.2 occ:1.00 SG A:CYS288 2.2 28.2 1.0 SG A:CYS285 2.3 22.6 1.0 SG A:CYS264 2.3 25.2 1.0 SG A:CYS267 2.3 28.4 1.0 CB A:CYS288 3.2 23.9 1.0 CB A:CYS264 3.2 24.8 1.0 CB A:CYS267 3.3 30.9 1.0 CB A:CYS285 3.4 22.7 1.0 N A:CYS267 3.7 31.0 1.0 N A:CYS285 3.9 21.3 1.0 CA A:CYS267 4.1 31.5 1.0 CA A:CYS285 4.2 20.8 1.0 N A:CYS288 4.3 23.3 1.0 NH1 A:ARG299 4.3 32.0 1.0 CA A:CYS288 4.3 24.1 1.0 O A:HOH596 4.4 48.7 1.0 CB A:ASN266 4.6 31.6 1.0 CB A:ALA269 4.6 31.1 1.0 O A:HOH579 4.6 33.0 1.0 CA A:CYS264 4.7 26.4 1.0 C A:ASN266 4.8 31.6 1.0 C A:CYS267 4.8 32.2 1.0 O A:CYS285 4.9 20.1 1.0 C A:CYS285 4.9 20.4 1.0 OD1 A:ASN266 5.0 35.9 1.0 N A:ALA269 5.0 31.3 1.0

Y.Chen, D.L.Bates, R.Dey, P.H.Chen, A.C.Machado, I.A.Laird-Offringa, R.Rohs, L.Chen. Dna Binding By Gata Transcription Factor Suggests Mechanisms of Dna Looping and Long-Range Gene Regulation. Cell Rep V. 2 1197 2012.
ISSN: ESSN 2211-1247
PubMed: 23142663
DOI: 10.1016/J.CELREP.2012.10.012