Zinc in PDB 4g8h: Crystal Structure of C-Lobe of Bovine Lactoferrin Complexed with Licofelone at 1.88 A Resolution

The structure of Crystal Structure of C-Lobe of Bovine Lactoferrin Complexed with Licofelone at 1.88 A Resolution, PDB code: 4g8h was solved by P.K.Shukla, L.Gautam, M.Sinha, P.Kaur, S.Sharma, T.P.Singh, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	62.65 / 1.88
Space group	P 1 21 1
Cell size a, b, c (Å), α, β, γ (°)	62.677, 49.945, 65.558, 90.00, 107.13, 90.00
R / Rfree (%)	16.4 / 21.2

The structure of Crystal Structure of C-Lobe of Bovine Lactoferrin Complexed with Licofelone at 1.88 A Resolution also contains other interesting chemical elements:

Iron	(Fe)	1 atom
Chlorine	(Cl)	1 atom

The binding sites of Zinc atom in the Crystal Structure of C-Lobe of Bovine Lactoferrin Complexed with Licofelone at 1.88 A Resolution (pdb code 4g8h). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Crystal Structure of C-Lobe of Bovine Lactoferrin Complexed with Licofelone at 1.88 A Resolution, PDB code: 4g8h:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Crystal Structure of C-Lobe of Bovine Lactoferrin Complexed with Licofelone at 1.88 A Resolution


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure of C-Lobe of Bovine Lactoferrin Complexed with Licofelone at 1.88 A Resolution within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn706 b:22.4 occ:1.00 O A:HOH1086 2.0 23.3 1.0 OE2 A:GLU659 2.2 21.4 1.0 OE1 A:GLU659 2.4 14.6 1.0 CD A:GLU659 2.6 17.0 1.0 O A:GLY653 3.8 26.2 1.0 CG A:GLU659 4.1 18.6 1.0 O A:ARG654 4.4 19.5 1.0 CA A:PRO655 4.6 17.6 1.0 O A:HOH1013 4.7 40.0 1.0 O A:HOH1054 4.8 60.3 1.0 N A:THR656 4.8 16.4 1.0 CB A:GLU659 4.9 15.5 1.0 CG2 A:THR656 4.9 17.3 1.0 C A:GLY653 5.0 25.7 1.0

Zinc binding site 2 out of 2 in the Crystal Structure of C-Lobe of Bovine Lactoferrin Complexed with Licofelone at 1.88 A Resolution


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Crystal Structure of C-Lobe of Bovine Lactoferrin Complexed with Licofelone at 1.88 A Resolution within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn707 b:24.6 occ:1.00 NE2 A:HIS588 2.1 18.2 1.0 CD2 A:HIS588 3.0 19.6 1.0 CE1 A:HIS588 3.1 16.6 1.0 O A:HOH1113 4.0 42.0 1.0 CG2 A:VAL591 4.2 22.5 1.0 CG A:HIS588 4.2 16.5 1.0 ND1 A:HIS588 4.2 19.3 1.0 CL1 A:LCF711 4.4 47.0 0.8 O A:HOH804 4.7 21.7 1.0

P.K.Shukla, L.Gautam, M.Sinha, P.Kaur, S.Sharma, T.P.Singh. Crystal Structure of C-Lobe of Bovine Lactoferrin Complexed with Licofelone at 1.88 A Resolution To Be Published.