Zinc in PDB 4g77: Crystal Structure of C-Lobe of Bovine Lactoferrin Complexed with Tolfenamic Acid at 1.98 A Resolution

The structure of Crystal Structure of C-Lobe of Bovine Lactoferrin Complexed with Tolfenamic Acid at 1.98 A Resolution, PDB code: 4g77 was solved by P.K.Shukla, L.Gautam, M.Sinha, P.Kaur, S.Sharma, T.P.Singh, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	62.51 / 1.98
Space group	P 1 21 1
Cell size a, b, c (Å), α, β, γ (°)	62.624, 49.869, 65.451, 90.00, 107.25, 90.00
R / Rfree (%)	16 / 21.1

The structure of Crystal Structure of C-Lobe of Bovine Lactoferrin Complexed with Tolfenamic Acid at 1.98 A Resolution also contains other interesting chemical elements:

Iron	(Fe)	1 atom
Chlorine	(Cl)	1 atom

The binding sites of Zinc atom in the Crystal Structure of C-Lobe of Bovine Lactoferrin Complexed with Tolfenamic Acid at 1.98 A Resolution (pdb code 4g77). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Crystal Structure of C-Lobe of Bovine Lactoferrin Complexed with Tolfenamic Acid at 1.98 A Resolution, PDB code: 4g77:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Crystal Structure of C-Lobe of Bovine Lactoferrin Complexed with Tolfenamic Acid at 1.98 A Resolution


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure of C-Lobe of Bovine Lactoferrin Complexed with Tolfenamic Acid at 1.98 A Resolution within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn704 b:25.5 occ:1.00 OE2 A:GLU659 2.1 27.1 1.0 OE1 A:GLU659 2.3 20.0 1.0 CD A:GLU659 2.5 22.6 1.0 O A:GLY653 3.8 30.0 1.0 CG A:GLU659 4.1 22.1 1.0 O A:ARG654 4.3 21.1 1.0 CA A:PRO655 4.6 21.1 1.0 O A:HOH890 4.7 52.5 1.0 N A:THR656 4.7 19.4 1.0 CB A:GLU659 4.8 19.9 1.0 C A:ARG654 4.9 24.1 1.0 C A:GLY653 5.0 28.5 1.0

Zinc binding site 2 out of 2 in the Crystal Structure of C-Lobe of Bovine Lactoferrin Complexed with Tolfenamic Acid at 1.98 A Resolution


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Crystal Structure of C-Lobe of Bovine Lactoferrin Complexed with Tolfenamic Acid at 1.98 A Resolution within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn705 b:29.2 occ:1.00 CL A:TLF711 1.8 45.4 1.0 NE2 A:HIS588 2.1 23.4 1.0 C2 A:TLF711 2.7 42.7 1.0 C3 A:TLF711 2.9 47.0 1.0 CE1 A:HIS588 3.0 24.9 1.0 CD2 A:HIS588 3.1 23.6 1.0 O A:HOH862 3.8 25.6 1.0 C1 A:TLF711 4.0 47.3 1.0 ND1 A:HIS588 4.1 24.7 1.0 CG2 A:VAL591 4.2 24.5 1.0 CG A:HIS588 4.2 21.3 1.0 C4 A:TLF711 4.3 43.0 1.0 C17 A:TLF711 4.6 49.2 1.0 O A:HOH824 4.7 24.6 1.0

P.K.Shukla, L.Gautam, M.Sinha, P.Kaur, S.Sharma, T.P.Singh. Crystal Structure of C-Lobe of Bovine Lactoferrin Complexed with Tolfenamic Acid at 1.98 A Resolution To Be Published.