Zinc in PDB 4bt6: Acetolactate Decarboxylase with A Bound Glycerol

All present enzymatic activity of Acetolactate Decarboxylase with A Bound Glycerol:
4.1.1.5;

The structure of Acetolactate Decarboxylase with A Bound Glycerol, PDB code: 4bt6 was solved by V.A Marlow, D.Rea, S.Najmudin, M.Wills, V.Fulop, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	40.82 / 1.60
Space group	P 32 2 1
Cell size a, b, c (Å), α, β, γ (°)	47.130, 47.130, 198.890, 90.00, 90.00, 120.00
R / Rfree (%)	17.045 / 21.222

The binding sites of Zinc atom in the Acetolactate Decarboxylase with A Bound Glycerol (pdb code 4bt6). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Acetolactate Decarboxylase with A Bound Glycerol, PDB code: 4bt6:

Zinc binding site 1 out of 1 in the Acetolactate Decarboxylase with A Bound Glycerol


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Acetolactate Decarboxylase with A Bound Glycerol within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn1257 b:6.0 occ:1.00 NE2 A:HIS194 2.1 6.9 1.0 ND1 A:HIS207 2.1 7.2 1.0 NE2 A:HIS196 2.1 8.2 1.0 O3 A:GOL1258 2.1 15.2 1.0 O2 A:GOL1258 2.2 8.9 1.0 OE1 A:GLU253 2.8 21.3 1.0 CE1 A:HIS207 2.9 7.3 1.0 CE1 A:HIS194 3.0 8.7 1.0 C2 A:GOL1258 3.1 11.6 1.0 CD2 A:HIS196 3.1 6.9 1.0 C3 A:GOL1258 3.1 11.0 1.0 CE1 A:HIS196 3.1 7.0 1.0 CD2 A:HIS194 3.2 6.9 1.0 CG A:HIS207 3.2 7.3 1.0 CD A:GLU253 3.6 17.6 1.0 OE2 A:GLU253 3.7 22.0 1.0 CB A:HIS207 3.7 7.3 1.0 OE1 A:GLU65 3.9 7.6 1.0 NH2 A:ARG145 4.0 8.0 1.0 NE2 A:HIS207 4.1 7.5 1.0 ND1 A:HIS194 4.1 6.8 1.0 ND1 A:HIS196 4.2 6.9 1.0 CG A:HIS196 4.3 6.8 1.0 CG A:HIS194 4.3 6.8 1.0 CD2 A:HIS207 4.3 7.5 1.0 C1 A:GOL1258 4.5 10.9 1.0 CA A:HIS207 4.6 7.2 1.0 CD A:GLU65 4.9 7.5 1.0 CZ A:ARG145 5.0 8.0 1.0

V.A.Marlow, D.Rea, S.Najmudin, M.Wills, V.Fulop. Structure and Mechanism of Acetolactate Decarboxylase. Acs Chem.Biol. V. 8 2339 2013.
ISSN: ISSN 1554-8929
PubMed: 23985082
DOI: 10.1021/CB400429H