Atomistry » Zinc » PDB 4ad9-4arf » 4ajx
Atomistry »
  Zinc »
    PDB 4ad9-4arf »
      4ajx »

Zinc in PDB 4ajx: Ligand Controlled Assembly of Hexamers, Dihexamers, and Linear Multihexamer Structures By An Engineered Acylated Insulin

Protein crystallography data

The structure of Ligand Controlled Assembly of Hexamers, Dihexamers, and Linear Multihexamer Structures By An Engineered Acylated Insulin, PDB code: 4ajx was solved by D.B.Steensgaard, G.Schluckebier, H.M.Strauss, M.Norrman, J.K.Thomsen, A.V.Friderichsen, S.Havelund, I.Jonassen, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 40.497 / 1.20
Space group P 1 21 1
Cell size a, b, c (Å), α, β, γ (°) 47.310, 62.490, 57.270, 90.00, 111.80, 90.00
R / Rfree (%) 14.05 / 15.96

Other elements in 4ajx:

The structure of Ligand Controlled Assembly of Hexamers, Dihexamers, and Linear Multihexamer Structures By An Engineered Acylated Insulin also contains other interesting chemical elements:

Sodium (Na) 2 atoms

Zinc Binding Sites:

The binding sites of Zinc atom in the Ligand Controlled Assembly of Hexamers, Dihexamers, and Linear Multihexamer Structures By An Engineered Acylated Insulin (pdb code 4ajx). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Ligand Controlled Assembly of Hexamers, Dihexamers, and Linear Multihexamer Structures By An Engineered Acylated Insulin, PDB code: 4ajx:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in 4ajx

Go back to Zinc Binding Sites List in 4ajx
Zinc binding site 1 out of 2 in the Ligand Controlled Assembly of Hexamers, Dihexamers, and Linear Multihexamer Structures By An Engineered Acylated Insulin


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Ligand Controlled Assembly of Hexamers, Dihexamers, and Linear Multihexamer Structures By An Engineered Acylated Insulin within 5.0Å range:
probe atom residue distance (Å) B Occ
F:Zn1029

b:11.6
occ:1.00
N1 L:IMD1031 1.8 18.6 1.0
NE2 L:HIS10 2.0 9.8 1.0
NE2 F:HIS10 2.0 13.6 1.0
NE2 B:HIS10 2.0 9.9 1.0
C5 L:IMD1031 2.8 17.5 1.0
C2 L:IMD1031 2.9 15.8 1.0
CE1 L:HIS10 2.9 12.6 1.0
H5 L:IMD1031 3.0 21.0 1.0
CE1 B:HIS10 3.0 12.2 1.0
CD2 F:HIS10 3.0 13.0 1.0
CE1 F:HIS10 3.0 14.5 1.0
CD2 B:HIS10 3.0 8.2 1.0
CD2 L:HIS10 3.1 9.2 1.0
HE1 L:HIS10 3.1 15.1 1.0
HE1 B:HIS10 3.1 14.7 1.0
HD2 F:HIS10 3.2 15.6 1.0
H2 L:IMD1031 3.2 19.0 1.0
HE1 F:HIS10 3.2 17.4 1.0
HD2 B:HIS10 3.2 9.9 1.0
HD2 L:HIS10 3.3 11.0 1.0
HB3 F:LEU6 3.9 13.8 1.0
C4 L:IMD1031 3.9 19.8 1.0
N3 L:IMD1031 4.0 20.4 1.0
ND1 L:HIS10 4.1 12.4 1.0
ND1 B:HIS10 4.1 12.4 1.0
ND1 F:HIS10 4.1 14.8 1.0
CG F:HIS10 4.1 12.2 1.0
CG L:HIS10 4.2 8.9 1.0
HB3 L:LEU6 4.2 17.3 1.0
CG B:HIS10 4.2 8.8 1.0
O D:HOH2040 4.3 37.2 1.0
HB3 B:LEU6 4.4 13.2 1.0
HD11 F:LEU6 4.7 22.7 1.0
O F:LEU6 4.7 11.3 1.0
HG F:SER9 4.8 16.8 0.2
O L:LEU6 4.8 10.9 1.0
H4 L:IMD1031 4.8 23.7 1.0
HD1 L:HIS10 4.8 14.9 1.0
HD1 B:HIS10 4.9 14.9 1.0
HG L:SER9 4.9 13.4 0.3
CB F:LEU6 4.9 11.5 1.0
HN3 L:IMD1031 4.9 24.5 1.0
HD1 F:HIS10 4.9 17.8 1.0
HD23 B:LEU6 4.9 17.1 1.0
O B:LEU6 5.0 10.2 1.0
O B:HOH2017 5.0 34.0 1.0
OG F:SER9 5.0 14.0 0.2

Zinc binding site 2 out of 2 in 4ajx

Go back to Zinc Binding Sites List in 4ajx
Zinc binding site 2 out of 2 in the Ligand Controlled Assembly of Hexamers, Dihexamers, and Linear Multihexamer Structures By An Engineered Acylated Insulin


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Ligand Controlled Assembly of Hexamers, Dihexamers, and Linear Multihexamer Structures By An Engineered Acylated Insulin within 5.0Å range:
probe atom residue distance (Å) B Occ
H:Zn1030

b:10.8
occ:1.00
O28 H:16E1031 1.9 11.5 1.0
NE2 D:HIS10 2.0 10.6 1.0
NE2 H:HIS10 2.0 9.8 1.0
NE2 J:HIS10 2.1 10.8 1.0
C26 H:16E1031 2.8 13.9 1.0
CE1 D:HIS10 3.0 12.2 1.0
O27 H:16E1031 3.0 12.3 1.0
CE1 H:HIS10 3.0 11.8 1.0
CE1 J:HIS10 3.0 14.5 1.0
CD2 H:HIS10 3.1 9.7 1.0
CD2 J:HIS10 3.1 9.7 1.0
CD2 D:HIS10 3.1 10.3 1.0
HE1 D:HIS10 3.1 14.7 1.0
HE1 H:HIS10 3.2 14.2 1.0
HE1 J:HIS10 3.2 17.4 1.0
HD2 J:HIS10 3.2 11.6 1.0
HD2 H:HIS10 3.3 11.6 1.0
HD2 D:HIS10 3.3 12.3 1.0
HB3 J:LEU6 3.8 14.4 1.0
HB3 H:LEU6 4.0 13.3 1.0
HB3 D:LEU6 4.1 14.4 1.0
ND1 D:HIS10 4.1 12.5 1.0
ND1 H:HIS10 4.1 11.1 1.0
ND1 J:HIS10 4.2 14.8 1.0
CG H:HIS10 4.2 9.3 1.0
CG D:HIS10 4.2 9.9 1.0
CG J:HIS10 4.2 10.4 1.0
C25 H:16E1031 4.2 14.5 1.0
O D:HOH2041 4.6 42.9 1.0
HD23 H:LEU6 4.6 17.3 1.0
O J:LEU6 4.7 12.6 1.0
HD11 J:LEU6 4.7 20.5 1.0
HD11 D:LEU6 4.7 19.9 1.0
HD11 H:LEU6 4.7 19.0 1.0
CB J:LEU6 4.7 12.0 1.0
O D:LEU6 4.9 10.9 1.0
C24 H:16E1031 4.9 18.9 1.0
HD1 D:HIS10 4.9 15.1 1.0
O H:LEU6 4.9 10.0 1.0
HD1 H:HIS10 4.9 13.3 1.0
CB H:LEU6 4.9 11.1 1.0
HD1 J:HIS10 4.9 17.7 1.0
CB D:LEU6 5.0 12.0 1.0

Reference:

D.B.Steensgaard, G.Schluckebier, H.M.Strauss, M.Norrman, J.K.Thomsen, A.V.Friderichsen, S.Havelund, I.Jonassen. Ligand Controlled Assembly of Hexamers, Dihexamers, and Linear Multihexamer Structures By the Engineered Acylated Insulin Degludec. Biochemistry V. 52 295 2013.
ISSN: ISSN 0006-2960
PubMed: 23256685
DOI: 10.1021/BI3008609
Page generated: Sat Oct 26 19:17:44 2024

Last articles

Zn in 9MJ5
Zn in 9HNW
Zn in 9G0L
Zn in 9FNE
Zn in 9DZN
Zn in 9E0I
Zn in 9D32
Zn in 9DAK
Zn in 8ZXC
Zn in 8ZUF
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy