Zinc in PDB 3w95: Crystal Structure of 2A Proteinase (C110A) From Enterovirus 71

All present enzymatic activity of Crystal Structure of 2A Proteinase (C110A) From Enterovirus 71:
2.7.7.48; 3.4.22.28; 3.4.22.29; 3.6.1.15;

The structure of Crystal Structure of 2A Proteinase (C110A) From Enterovirus 71, PDB code: 3w95 was solved by Z.Mu, X.Gao, S.Cui, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	29.26 / 1.85
Space group	P 41 21 2
Cell size a, b, c (Å), α, β, γ (°)	92.524, 92.524, 36.127, 90.00, 90.00, 90.00
R / Rfree (%)	21.7 / 24.9

The binding sites of Zinc atom in the Crystal Structure of 2A Proteinase (C110A) From Enterovirus 71 (pdb code 3w95). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Crystal Structure of 2A Proteinase (C110A) From Enterovirus 71, PDB code: 3w95:

Zinc binding site 1 out of 1 in the Crystal Structure of 2A Proteinase (C110A) From Enterovirus 71


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure of 2A Proteinase (C110A) From Enterovirus 71 within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn201 b:19.5 occ:1.00 ND1 A:HIS118 2.2 17.7 1.0 SG A:CYS56 2.3 17.1 1.0 SG A:CYS116 2.4 16.0 1.0 SG A:CYS58 2.4 16.3 1.0 HB2 A:CYS58 2.7 19.1 1.0 HB2 A:HIS118 2.9 21.8 1.0 HB2 A:CYS116 3.1 16.6 1.0 CB A:CYS58 3.1 15.9 1.0 CE1 A:HIS118 3.1 22.1 1.0 CB A:CYS56 3.2 21.0 1.0 HB3 A:CYS56 3.2 25.2 1.0 CG A:HIS118 3.2 19.4 1.0 HB2 A:CYS56 3.2 25.2 1.0 CB A:CYS116 3.3 13.9 1.0 HE1 A:HIS118 3.3 26.5 1.0 H A:HIS118 3.3 18.9 1.0 CB A:HIS118 3.5 18.2 1.0 HB3 A:CYS116 3.6 16.6 1.0 H A:CYS58 3.6 18.7 1.0 HB3 A:CYS58 3.7 19.1 1.0 HB1 A:ALA54 3.8 23.0 1.0 N A:HIS118 4.0 15.8 1.0 O A:HOH339 4.1 24.0 1.0 H A:GLN117 4.2 20.9 1.0 N A:CYS58 4.3 15.6 1.0 HB3 A:HIS118 4.3 21.8 1.0 CA A:CYS58 4.3 14.3 1.0 NE2 A:HIS118 4.3 16.2 1.0 CD2 A:HIS118 4.3 18.4 1.0 CA A:HIS118 4.4 17.1 1.0 HG22 A:VAL121 4.5 18.9 1.0 H A:CYS56 4.5 20.6 1.0 N A:GLN117 4.6 17.4 1.0 HB2 A:ALA54 4.6 23.0 1.0 CA A:CYS56 4.6 20.4 1.0 CB A:ALA54 4.6 19.2 1.0 HH11 A:ARG138 4.6 15.3 1.0 O A:HOH403 4.6 31.2 1.0 CA A:CYS116 4.6 19.3 1.0 HA A:CYS58 4.7 17.1 1.0 HG21 A:VAL121 4.8 18.9 1.0 C A:CYS116 4.9 16.5 1.0 N A:CYS56 5.0 17.2 1.0 HB3 A:ALA54 5.0 23.0 1.0 CG2 A:VAL121 5.0 15.8 1.0

Z.Mu, B.Wang, X.Zhang, X.Gao, B.Qin, Z.Zhao, S.Cui. Crystal Structure of 2A Proteinase From Hand, Foot and Mouth Disease Virus J.Mol.Biol. V. 425 4530 2013.
ISSN: ISSN 0022-2836
PubMed: 23973886
DOI: 10.1016/J.JMB.2013.08.016