Zinc in PDB 3w80: Crystal Structure of Dodecamer Human Insulin with Double C-Axis Length of the Hexamer 2 Zn Insulin Cell

The structure of Crystal Structure of Dodecamer Human Insulin with Double C-Axis Length of the Hexamer 2 Zn Insulin Cell, PDB code: 3w80 was solved by M.Murayoshi, K.Sasaki, N.Sakabe, K.Sakabe, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	10.00 / 1.40
Space group	H 3
Cell size a, b, c (Å), α, β, γ (°)	82.720, 82.720, 68.140, 90.00, 90.00, 120.00
R / Rfree (%)	18.2 / 24.8

The binding sites of Zinc atom in the Crystal Structure of Dodecamer Human Insulin with Double C-Axis Length of the Hexamer 2 Zn Insulin Cell (pdb code 3w80). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 4 binding sites of Zinc where determined in the Crystal Structure of Dodecamer Human Insulin with Double C-Axis Length of the Hexamer 2 Zn Insulin Cell, PDB code: 3w80:
Jump to Zinc binding site number: 1; 2; 3; 4;

Zinc binding site 1 out of 4 in the Crystal Structure of Dodecamer Human Insulin with Double C-Axis Length of the Hexamer 2 Zn Insulin Cell


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure of Dodecamer Human Insulin with Double C-Axis Length of the Hexamer 2 Zn Insulin Cell within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn101 b:11.0 occ:0.33 NE2 B:HIS10 2.1 9.3 1.0 O B:HOH202 2.3 30.7 1.0 CE1 B:HIS10 3.0 10.9 1.0 CD2 B:HIS10 3.1 9.0 1.0 O B:HOH234 4.0 46.8 0.3 ND1 B:HIS10 4.1 12.7 1.0 CG B:HIS10 4.2 10.3 1.0 O B:HOH250 4.2 92.5 1.0 O B:HOH216 4.5 30.0 1.0

Zinc binding site 2 out of 4 in the Crystal Structure of Dodecamer Human Insulin with Double C-Axis Length of the Hexamer 2 Zn Insulin Cell


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Crystal Structure of Dodecamer Human Insulin with Double C-Axis Length of the Hexamer 2 Zn Insulin Cell within 5.0Å range: probe atom residue distance (Å) B Occ D:Zn101 b:3.1 occ:0.33 NE2 D:HIS10 2.0 9.4 1.0 O D:HOH201 2.0 21.1 1.0 CE1 D:HIS10 2.8 13.0 1.0 CD2 D:HIS10 3.1 12.0 1.0 ND1 D:HIS10 4.0 12.7 1.0 CG D:HIS10 4.2 10.0 1.0 O D:HOH220 4.7 29.1 1.0 O D:HOH233 4.8 59.4 1.0

Zinc binding site 3 out of 4 in the Crystal Structure of Dodecamer Human Insulin with Double C-Axis Length of the Hexamer 2 Zn Insulin Cell


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 3 of Crystal Structure of Dodecamer Human Insulin with Double C-Axis Length of the Hexamer 2 Zn Insulin Cell within 5.0Å range: probe atom residue distance (Å) B Occ F:Zn101 b:11.3 occ:0.33 NE2 F:HIS10 2.0 7.8 1.0 O F:HOH203 2.3 31.1 1.0 CE1 F:HIS10 3.0 9.9 1.0 CD2 F:HIS10 3.1 8.7 1.0 ND1 F:HIS10 4.1 10.9 1.0 O F:HOH232 4.2 54.8 0.3 O F:HOH247 4.2 65.3 1.0 CG F:HIS10 4.2 9.1 1.0 O F:HOH217 4.5 26.0 1.0

Zinc binding site 4 out of 4 in the Crystal Structure of Dodecamer Human Insulin with Double C-Axis Length of the Hexamer 2 Zn Insulin Cell


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 4 of Crystal Structure of Dodecamer Human Insulin with Double C-Axis Length of the Hexamer 2 Zn Insulin Cell within 5.0Å range: probe atom residue distance (Å) B Occ H:Zn101 b:22.8 occ:0.33 NE2 H:HIS10 2.1 12.7 1.0 O H:HOH201 2.4 20.1 1.0 CD2 H:HIS10 3.0 5.7 1.0 CE1 H:HIS10 3.1 9.8 1.0 CG H:HIS10 4.2 9.0 1.0 ND1 H:HIS10 4.2 10.2 1.0 O H:HOH219 4.7 33.2 1.0

M.Murayoshi, K.Sasaki, N.Sakabe, K.Sakabe. Crystal Structure of Dodecamer Insulin with Double C-Axis Length of the Hexamer 2 Zn Insulin Celll To Be Published.