Zinc in PDB 3v1g: Forestalling Insulin Fibrillation By Insertion of A Chiral Clamp Mechanism-Based Application of Protein Engineering to Global Health

The structure of Forestalling Insulin Fibrillation By Insertion of A Chiral Clamp Mechanism-Based Application of Protein Engineering to Global Health, PDB code: 3v1g was solved by Z.L.Wan, Q.X.Hua, N.P.Wickramasinghe, K.Huang, A.T.Petkova, S.Q.Hu, N.B.Phillips, I.J.Yeh, J.Whittake, F.Ismail-Beigi, P.G.Katsoyyannis, R.Tycko, M.A.Weiss, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	39.54 / 2.20
Space group	H 3
Cell size a, b, c (Å), α, β, γ (°)	79.081, 79.081, 37.402, 90.00, 90.00, 120.00
R / Rfree (%)	22.9 / 32.3

The structure of Forestalling Insulin Fibrillation By Insertion of A Chiral Clamp Mechanism-Based Application of Protein Engineering to Global Health also contains other interesting chemical elements:

Chlorine

(Cl)

1 atom

The binding sites of Zinc atom in the Forestalling Insulin Fibrillation By Insertion of A Chiral Clamp Mechanism-Based Application of Protein Engineering to Global Health (pdb code 3v1g). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Forestalling Insulin Fibrillation By Insertion of A Chiral Clamp Mechanism-Based Application of Protein Engineering to Global Health, PDB code: 3v1g:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Forestalling Insulin Fibrillation By Insertion of A Chiral Clamp Mechanism-Based Application of Protein Engineering to Global Health


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Forestalling Insulin Fibrillation By Insertion of A Chiral Clamp Mechanism-Based Application of Protein Engineering to Global Health within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn31 b:1.7 occ:0.33 NE2 B:HIS10 2.1 29.9 1.0 CE1 B:HIS10 3.0 32.3 1.0 CD2 B:HIS10 3.1 29.6 1.0 ND1 B:HIS10 4.2 30.0 1.0 CG B:HIS10 4.2 30.2 1.0 O B:HOH32 4.2 64.3 1.0 O B:HOH77 4.6 38.4 1.0

Zinc binding site 2 out of 2 in the Forestalling Insulin Fibrillation By Insertion of A Chiral Clamp Mechanism-Based Application of Protein Engineering to Global Health


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Forestalling Insulin Fibrillation By Insertion of A Chiral Clamp Mechanism-Based Application of Protein Engineering to Global Health within 5.0Å range: probe atom residue distance (Å) B Occ D:Zn31 b:1.7 occ:0.33 NE2 D:HIS10 2.1 22.5 1.0 CL D:CL32 2.2 1.7 0.3 CD2 D:HIS10 3.0 19.7 1.0 CE1 D:HIS10 3.1 21.3 1.0 CG D:HIS10 4.2 21.4 1.0 ND1 D:HIS10 4.2 26.2 1.0 O D:LEU6 4.5 23.2 1.0 CB D:LEU6 4.8 22.7 1.0 O D:HOH36 5.0 32.4 1.0

Z.L.Wan, Q.X.Hua, N.P.Wickramasinghe, K.Huang, A.T.Petkova, S.Q.Hu, N.B.Phillips, I.J.Yeh, J.Whittake, F.Ismail-Beigi, P.G.Katsoyyannis, R.Tycko, M.A.Weiss. Forestalling Insulin Fibrillation By Insertion of A Chiral Clamp Mechanism-Based Application of Protein Engineering to Global Health To Be Published.