Zinc in PDB 3uik: Crystal Structure of Human Survivin Mutant K62Y/H80W in Complex with H3(1-10) Peptide

Protein crystallography data

The structure of Crystal Structure of Human Survivin Mutant K62Y/H80W in Complex with H3(1-10) Peptide, PDB code: 3uik was solved by J.Du, D.J.Patel, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 27.68 / 2.70
Space group C 1 2 1
Cell size a, b, c (Å), α, β, γ (°) 115.503, 71.389, 81.874, 90.00, 128.73, 90.00
R / Rfree (%) 21.9 / 28.1

Zinc Binding Sites:

The binding sites of Zinc atom in the Crystal Structure of Human Survivin Mutant K62Y/H80W in Complex with H3(1-10) Peptide (pdb code 3uik). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Crystal Structure of Human Survivin Mutant K62Y/H80W in Complex with H3(1-10) Peptide, PDB code: 3uik:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in 3uik

Go back to Zinc Binding Sites List in 3uik
Zinc binding site 1 out of 2 in the Crystal Structure of Human Survivin Mutant K62Y/H80W in Complex with H3(1-10) Peptide


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure of Human Survivin Mutant K62Y/H80W in Complex with H3(1-10) Peptide within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Zn341

b:94.0
occ:1.00
SG A:CYS60 2.2 93.2 1.0
SG A:CYS84 2.4 0.4 1.0
SG A:CYS57 2.4 80.0 1.0
NE2 A:HIS77 2.5 0.6 1.0
CE1 A:HIS77 2.7 0.0 1.0
CB A:CYS84 2.8 78.9 1.0
CB A:CYS60 3.0 62.2 1.0
CB A:CYS57 3.4 92.7 1.0
N A:CYS60 3.4 74.7 1.0
CD2 A:HIS77 3.8 0.4 1.0
CA A:CYS60 3.8 71.8 1.0
ND1 A:HIS77 4.1 0.1 1.0
CB A:PHE59 4.1 72.2 1.0
CA A:CYS84 4.3 97.2 1.0
C A:PHE59 4.5 77.6 1.0
CG A:HIS77 4.6 0.1 1.0
C A:CYS60 4.7 72.2 1.0
OG A:SER81 4.7 83.0 1.0
CA A:PHE59 4.7 66.3 1.0
CA A:CYS57 4.8 75.3 1.0
N A:PHE61 4.8 75.6 1.0
N A:PHE59 4.9 71.2 1.0
CD2 A:PHE59 4.9 0.4 1.0
CB A:PHE86 4.9 0.8 1.0
CG A:PHE59 5.0 92.2 1.0

Zinc binding site 2 out of 2 in 3uik

Go back to Zinc Binding Sites List in 3uik
Zinc binding site 2 out of 2 in the Crystal Structure of Human Survivin Mutant K62Y/H80W in Complex with H3(1-10) Peptide


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Crystal Structure of Human Survivin Mutant K62Y/H80W in Complex with H3(1-10) Peptide within 5.0Å range:
probe atom residue distance (Å) B Occ
B:Zn341

b:0.2
occ:1.00
SG B:CYS60 2.2 0.4 1.0
SG B:CYS57 2.3 99.3 1.0
NE2 B:HIS77 2.4 0.2 1.0
SG B:CYS84 2.4 0.5 1.0
CE1 B:HIS77 2.6 0.3 1.0
CB B:CYS57 3.1 93.9 1.0
CB B:CYS84 3.2 0.7 1.0
CB B:CYS60 3.4 0.4 1.0
CD2 B:HIS77 3.7 0.9 1.0
N B:CYS60 3.8 0.6 1.0
ND1 B:HIS77 4.0 0.2 1.0
CA B:CYS60 4.2 0.3 1.0
CG B:HIS77 4.5 0.2 1.0
CA B:CYS84 4.5 0.4 1.0
CB B:PHE59 4.5 96.0 1.0
CA B:CYS57 4.6 0.6 1.0
C B:PHE59 4.9 0.5 1.0
C B:CYS60 4.9 0.1 1.0

Reference:

J.Du, A.E.Kelly, H.Funabiki, D.J.Patel. Structural Basis For Recognition of H3T3PH and Smac/Diablo N-Terminal Peptides By Human Survivin. Structure V. 20 185 2012.
ISSN: ISSN 0969-2126
PubMed: 22244766
DOI: 10.1016/J.STR.2011.12.001
Page generated: Wed Dec 16 04:54:52 2020

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