Zinc in PDB 3uii: Crystal Structure of Human Survivin in Complex with H3(1-10) Peptide

The structure of Crystal Structure of Human Survivin in Complex with H3(1-10) Peptide, PDB code: 3uii was solved by J.Du, D.J.Patel, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	29.27 / 2.60
Space group	C 1 2 1
Cell size a, b, c (Å), α, β, γ (°)	115.250, 71.256, 81.636, 90.00, 128.46, 90.00
R / Rfree (%)	22.2 / 27.3

The binding sites of Zinc atom in the Crystal Structure of Human Survivin in Complex with H3(1-10) Peptide (pdb code 3uii). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Crystal Structure of Human Survivin in Complex with H3(1-10) Peptide, PDB code: 3uii:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Crystal Structure of Human Survivin in Complex with H3(1-10) Peptide


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure of Human Survivin in Complex with H3(1-10) Peptide within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn341 b:73.9 occ:1.00 NE2 A:HIS77 2.2 92.6 1.0 SG A:CYS84 2.2 77.7 1.0 SG A:CYS57 2.2 57.5 1.0 SG A:CYS60 2.3 70.6 1.0 CE1 A:HIS77 2.9 89.4 1.0 CB A:CYS57 3.1 60.4 1.0 CB A:CYS84 3.1 66.0 1.0 CB A:CYS60 3.3 69.5 1.0 CD2 A:HIS77 3.3 91.2 1.0 N A:CYS60 3.7 58.0 1.0 CA A:CYS60 4.1 62.8 1.0 ND1 A:HIS77 4.1 89.0 1.0 CG A:HIS77 4.3 88.2 1.0 CA A:CYS84 4.4 77.5 1.0 CA A:CYS57 4.5 61.7 1.0 CB A:PHE59 4.5 59.1 1.0 OG A:SER81 4.6 81.5 1.0 C A:PHE59 4.7 63.7 1.0 C A:CYS60 4.8 58.9 1.0 CB A:PHE86 5.0 74.0 1.0 CA A:PHE59 5.0 58.0 1.0 N A:PHE59 5.0 57.6 1.0

Zinc binding site 2 out of 2 in the Crystal Structure of Human Survivin in Complex with H3(1-10) Peptide


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Crystal Structure of Human Survivin in Complex with H3(1-10) Peptide within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn341 b:79.0 occ:1.00 SG B:CYS57 2.2 64.7 1.0 SG B:CYS84 2.2 90.1 1.0 NE2 B:HIS77 2.3 99.0 1.0 SG B:CYS60 2.4 82.3 1.0 CE1 B:HIS77 2.7 95.8 1.0 CB B:CYS57 3.1 59.2 1.0 CB B:CYS84 3.1 88.1 1.0 CB B:CYS60 3.2 72.9 1.0 CD2 B:HIS77 3.6 94.9 1.0 N B:CYS60 3.8 67.8 1.0 ND1 B:HIS77 4.0 93.1 1.0 CA B:CYS60 4.1 67.0 1.0 CA B:CYS84 4.4 78.3 1.0 CG B:HIS77 4.5 92.5 1.0 OG B:SER81 4.5 0.7 1.0 CA B:CYS57 4.5 70.8 1.0 CB B:PHE59 4.6 59.0 1.0 C B:PHE59 4.8 72.9 1.0 C B:CYS60 4.9 64.7 1.0 N B:PHE61 5.0 63.5 1.0 CB B:SER81 5.0 1.0 1.0

J.Du, A.E.Kelly, H.Funabiki, D.J.Patel. Structural Basis For Recognition of H3T3PH and Smac/Diablo N-Terminal Peptides By Human Survivin. Structure V. 20 185 2012.
ISSN: ISSN 0969-2126
PubMed: 22244766
DOI: 10.1016/J.STR.2011.12.001