Zinc in PDB 3uig: Crystal Structure of Human Survivin in Complex with T3 Phosphorylated H3(1-15) Peptide

The structure of Crystal Structure of Human Survivin in Complex with T3 Phosphorylated H3(1-15) Peptide, PDB code: 3uig was solved by J.Du, D.J.Patel, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	31.07 / 2.40
Space group	C 1 2 1
Cell size a, b, c (Å), α, β, γ (°)	115.778, 71.042, 82.287, 90.00, 128.81, 90.00
R / Rfree (%)	21.3 / 25

The binding sites of Zinc atom in the Crystal Structure of Human Survivin in Complex with T3 Phosphorylated H3(1-15) Peptide (pdb code 3uig). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Crystal Structure of Human Survivin in Complex with T3 Phosphorylated H3(1-15) Peptide, PDB code: 3uig:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Crystal Structure of Human Survivin in Complex with T3 Phosphorylated H3(1-15) Peptide


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure of Human Survivin in Complex with T3 Phosphorylated H3(1-15) Peptide within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn201 b:70.9 occ:1.00 NE2 A:HIS77 2.3 86.7 1.0 SG A:CYS57 2.3 68.8 1.0 SG A:CYS84 2.3 82.1 1.0 SG A:CYS60 2.3 72.8 1.0 CE1 A:HIS77 2.9 82.7 1.0 CB A:CYS57 3.0 70.4 1.0 CB A:CYS84 3.1 84.7 1.0 CB A:CYS60 3.2 68.0 1.0 CD2 A:HIS77 3.5 91.8 1.0 N A:CYS60 3.7 71.5 1.0 CA A:CYS60 4.0 68.3 1.0 ND1 A:HIS77 4.1 87.7 1.0 CA A:CYS57 4.4 68.1 1.0 CG A:HIS77 4.4 90.8 1.0 CA A:CYS84 4.5 89.4 1.0 OG A:SER81 4.6 85.3 1.0 CB A:PHE59 4.6 61.4 1.0 C A:PHE59 4.7 78.3 1.0 C A:CYS60 4.8 69.7 1.0 CB A:SER81 4.9 82.3 1.0 N A:PHE61 5.0 71.6 1.0 C A:CYS57 5.0 56.3 1.0

Zinc binding site 2 out of 2 in the Crystal Structure of Human Survivin in Complex with T3 Phosphorylated H3(1-15) Peptide


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Crystal Structure of Human Survivin in Complex with T3 Phosphorylated H3(1-15) Peptide within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn201 b:75.1 occ:1.00 NE2 B:HIS77 2.2 0.7 1.0 SG B:CYS57 2.2 75.5 1.0 SG B:CYS60 2.3 84.2 1.0 SG B:CYS84 2.4 84.8 1.0 CE1 B:HIS77 2.6 0.9 1.0 CB B:CYS57 3.2 66.0 1.0 CB B:CYS84 3.3 84.5 1.0 CB B:CYS60 3.3 76.7 1.0 CD2 B:HIS77 3.5 0.2 1.0 N B:CYS60 3.6 70.1 1.0 ND1 B:HIS77 3.9 0.3 1.0 CA B:CYS60 4.0 70.9 1.0 CG B:HIS77 4.3 0.1 1.0 CB B:PHE59 4.5 64.5 1.0 CA B:CYS57 4.6 81.2 1.0 C B:PHE59 4.6 80.2 1.0 CA B:CYS84 4.7 88.6 1.0 CB B:SER81 4.7 0.9 1.0 OG B:SER81 4.8 0.0 1.0 CB B:PHE86 4.8 65.9 1.0 C B:CYS60 4.9 75.8 1.0 N B:PHE61 4.9 84.9 1.0 CA B:PHE59 4.9 65.2 1.0

J.Du, A.E.Kelly, H.Funabiki, D.J.Patel. Structural Basis For Recognition of H3T3PH and Smac/Diablo N-Terminal Peptides By Human Survivin. Structure V. 20 185 2012.
ISSN: ISSN 0969-2126
PubMed: 22244766
DOI: 10.1016/J.STR.2011.12.001