Zinc in PDB 3uei: Crystal Structure of Human Survivin E65A Mutant

The structure of Crystal Structure of Human Survivin E65A Mutant, PDB code: 3uei was solved by E.Niedzialkowska, P.J.Porebski, F.Wang, J.M.Higgins, P.T.Stukenberg, W.Minor, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	50.00 / 2.70
Space group	C 1 2 1
Cell size a, b, c (Å), α, β, γ (°)	113.561, 71.213, 83.203, 90.00, 129.66, 90.00
R / Rfree (%)	17.7 / 22.8

The binding sites of Zinc atom in the Crystal Structure of Human Survivin E65A Mutant (pdb code 3uei). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Crystal Structure of Human Survivin E65A Mutant, PDB code: 3uei:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Crystal Structure of Human Survivin E65A Mutant


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure of Human Survivin E65A Mutant within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn143 b:70.2 occ:1.00 NE2 A:HIS77 2.0 85.7 1.0 SG A:CYS57 2.1 74.3 1.0 SG A:CYS84 2.2 75.0 1.0 SG A:CYS60 2.2 68.7 1.0 CE1 A:HIS77 2.6 84.0 1.0 CB A:CYS57 3.0 73.2 1.0 CB A:CYS60 3.2 68.1 1.0 CB A:CYS84 3.2 82.3 1.0 CD2 A:HIS77 3.3 84.4 1.0 N A:CYS60 3.6 69.6 1.0 ND1 A:HIS77 3.9 78.0 1.0 CA A:CYS60 4.0 69.6 1.0 CG A:HIS77 4.2 81.8 1.0 CA A:CYS57 4.4 70.8 1.0 OG A:SER81 4.5 82.1 1.0 CA A:CYS84 4.6 84.1 1.0 CB A:PHE59 4.6 60.8 1.0 C A:PHE59 4.7 67.1 1.0 C A:CYS60 4.8 72.9 1.0 CB A:SER81 4.8 82.6 1.0 N A:PHE61 4.9 72.5 1.0 CB A:PHE86 5.0 74.0 1.0 C A:CYS57 5.0 71.4 1.0

Zinc binding site 2 out of 2 in the Crystal Structure of Human Survivin E65A Mutant


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Crystal Structure of Human Survivin E65A Mutant within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn143 b:71.8 occ:1.00 NE2 B:HIS77 2.0 96.0 1.0 SG B:CYS57 2.2 67.0 1.0 SG B:CYS84 2.3 78.9 1.0 SG B:CYS60 2.3 76.4 1.0 CE1 B:HIS77 2.6 88.2 1.0 CB B:CYS57 3.0 65.6 1.0 CB B:CYS84 3.1 84.2 1.0 CB B:CYS60 3.1 76.7 1.0 CD2 B:HIS77 3.3 89.5 1.0 N B:CYS60 3.6 64.8 1.0 ND1 B:HIS77 3.9 72.7 1.0 CA B:CYS60 3.9 72.1 1.0 CG B:HIS77 4.2 79.8 1.0 CA B:CYS57 4.5 63.1 1.0 CA B:CYS84 4.5 87.0 1.0 OG B:SER81 4.5 98.3 1.0 CB B:PHE59 4.7 66.5 1.0 C B:PHE59 4.7 60.4 1.0 C B:CYS60 4.8 69.0 1.0 CB B:SER81 4.8 0.0 1.0 N B:PHE61 4.9 67.9 1.0

E.Niedzialkowska, F.Wang, P.J.Porebski, W.Minor, J.M.Higgins, P.T.Stukenberg. Molecular Basis For Phosphospecific Recognition of Histone H3 Tails By Survivin Paralogues at Inner Centromeres. Mol Biol Cell V. 23 1457 2012.
PubMed: 22357620
DOI: 10.1091/MBC.E11-11-0904