Zinc in PDB 3uee: Crystal Structure of Human Survivin K62A Mutant Bound to N-Terminal Histone H3

The structure of Crystal Structure of Human Survivin K62A Mutant Bound to N-Terminal Histone H3, PDB code: 3uee was solved by E.Niedzialkowska, P.J.Porebski, F.Wang, J.M.Higgins, P.T.Stukenberg, W.Minor, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	50.00 / 2.61
Space group	C 1 2 1
Cell size a, b, c (Å), α, β, γ (°)	113.888, 70.872, 82.037, 90.00, 129.52, 90.00
R / Rfree (%)	18.5 / 23.7

The binding sites of Zinc atom in the Crystal Structure of Human Survivin K62A Mutant Bound to N-Terminal Histone H3 (pdb code 3uee). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Crystal Structure of Human Survivin K62A Mutant Bound to N-Terminal Histone H3, PDB code: 3uee:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Crystal Structure of Human Survivin K62A Mutant Bound to N-Terminal Histone H3


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure of Human Survivin K62A Mutant Bound to N-Terminal Histone H3 within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn143 b:58.6 occ:1.00 NE2 A:HIS77 2.1 86.8 1.0 SG A:CYS57 2.2 54.7 1.0 SG A:CYS84 2.3 66.7 1.0 SG A:CYS60 2.3 59.0 1.0 CE1 A:HIS77 2.5 78.5 1.0 CB A:CYS57 3.0 55.0 1.0 CB A:CYS84 3.0 71.0 1.0 CB A:CYS60 3.2 59.5 1.0 CD2 A:HIS77 3.4 76.6 1.0 N A:CYS60 3.6 59.2 1.0 ND1 A:HIS77 3.8 83.3 1.0 CA A:CYS60 4.0 58.7 1.0 CG A:HIS77 4.2 77.5 1.0 CA A:CYS57 4.5 51.7 1.0 CA A:CYS84 4.5 78.5 1.0 OG A:SER81 4.5 82.0 1.0 CB A:PHE59 4.5 54.1 1.0 C A:PHE59 4.7 56.7 1.0 C A:CYS60 4.7 60.9 1.0 CB A:SER81 4.9 94.8 1.0 N A:PHE61 4.9 60.7 1.0 N A:PHE59 4.9 50.7 1.0 C A:CYS57 5.0 50.6 1.0 CA A:PHE59 5.0 52.2 1.0

Zinc binding site 2 out of 2 in the Crystal Structure of Human Survivin K62A Mutant Bound to N-Terminal Histone H3


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Crystal Structure of Human Survivin K62A Mutant Bound to N-Terminal Histone H3 within 5.0Å range: probe atom residue distance (Å) B Occ C:Zn143 b:60.0 occ:1.00 NE2 C:HIS77 2.1 89.5 1.0 SG C:CYS57 2.2 52.6 1.0 SG C:CYS84 2.3 64.6 1.0 SG C:CYS60 2.3 64.2 1.0 CE1 C:HIS77 2.5 79.2 1.0 CB C:CYS57 3.0 56.1 1.0 CB C:CYS84 3.0 70.9 1.0 CB C:CYS60 3.2 61.9 1.0 CD2 C:HIS77 3.4 86.9 1.0 N C:CYS60 3.6 58.0 1.0 ND1 C:HIS77 3.8 78.2 1.0 CA C:CYS60 4.0 61.6 1.0 CG C:HIS77 4.2 81.8 1.0 CA C:CYS84 4.4 73.6 1.0 OG C:SER81 4.4 95.8 1.0 CA C:CYS57 4.5 56.5 1.0 CB C:PHE59 4.6 52.4 1.0 C C:PHE59 4.7 55.8 1.0 C C:CYS60 4.7 61.0 1.0 CB C:SER81 4.8 94.4 1.0 N C:PHE61 4.9 62.6 1.0 C C:CYS57 5.0 53.9 1.0

E.Niedzialkowska, F.Wang, P.J.Porebski, W.Minor, J.M.Higgins, P.T.Stukenberg. Molecular Basis For Phosphospecific Recognition of Histone H3 Tails By Survivin Paralogues at Inner Centromeres. Mol.Biol.Cell V. 23 1457 2012.
ISSN: ISSN 1059-1524
PubMed: 22357620
DOI: 10.1091/MBC.E11-11-0904