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Zinc in PDB 3udr: Crystal Structure of Bace with Compound 14Enzymatic activity of Crystal Structure of Bace with Compound 14
All present enzymatic activity of Crystal Structure of Bace with Compound 14:
3.4.23.46; Protein crystallography data
The structure of Crystal Structure of Bace with Compound 14, PDB code: 3udr
was solved by
I.V.Efremov,
F.F.Vajdos,
K.Borzilleri,
S.Capetta,
P.Dorff,
J.Dutra,
M.Mansour,
C.Oborski,
T.O'connell,
T.J.O'sullivan,
J.Pandit,
H.Wang,
J.Withka,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Zinc Binding Sites:
The binding sites of Zinc atom in the Crystal Structure of Bace with Compound 14
(pdb code 3udr). This binding sites where shown within
5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Crystal Structure of Bace with Compound 14, PDB code: 3udr: Zinc binding site 1 out of 1 in 3udrGo back to Zinc Binding Sites List in 3udr
Zinc binding site 1 out
of 1 in the Crystal Structure of Bace with Compound 14
Mono view Stereo pair view
Reference:
I.V.Efremov,
F.F.Vajdos,
K.A.Borzilleri,
S.Capetta,
H.Chen,
P.H.Dorff,
J.K.Dutra,
S.W.Goldstein,
M.Mansour,
A.Mccoll,
S.Noell,
C.E.Oborski,
T.N.O'connell,
T.J.O'sullivan,
J.Pandit,
H.Wang,
B.Wei,
J.M.Withka.
Discovery and Optimization of A Novel Spiropyrrolidine Inhibitor of {Beta}-Secretase (BACE1) Through Fragment-Based Drug Design. J.Med.Chem. V. 55 9069 2012.
Page generated: Wed Dec 16 04:54:15 2020
ISSN: ISSN 0022-2623 PubMed: 22468999 DOI: 10.1021/JM201715D |
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