Zinc in PDB 3qzv: Crystal Structure of Bptf Phd-Linker-Bromo in Complex with Histone H4K12AC Peptide

The structure of Crystal Structure of Bptf Phd-Linker-Bromo in Complex with Histone H4K12AC Peptide, PDB code: 3qzv was solved by H.Li, A.J.Ruthenburg, D.J.Patel, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	20.00 / 2.00
Space group	C 1 2 1
Cell size a, b, c (Å), α, β, γ (°)	65.525, 38.513, 87.752, 90.00, 111.20, 90.00
R / Rfree (%)	18.2 / 23.4

The binding sites of Zinc atom in the Crystal Structure of Bptf Phd-Linker-Bromo in Complex with Histone H4K12AC Peptide (pdb code 3qzv). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Crystal Structure of Bptf Phd-Linker-Bromo in Complex with Histone H4K12AC Peptide, PDB code: 3qzv:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Crystal Structure of Bptf Phd-Linker-Bromo in Complex with Histone H4K12AC Peptide


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure of Bptf Phd-Linker-Bromo in Complex with Histone H4K12AC Peptide within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn175 b:57.0 occ:1.00 ND1 A:HIS34 2.2 53.4 1.0 SG A:CYS11 2.3 53.5 1.0 SG A:CYS37 2.3 62.0 1.0 SG A:CYS13 2.3 63.8 1.0 CG A:HIS34 3.0 52.3 1.0 CE1 A:HIS34 3.2 53.7 1.0 CB A:HIS34 3.2 52.0 1.0 CB A:CYS11 3.2 56.8 1.0 CB A:CYS37 3.3 59.2 1.0 CB A:CYS13 3.3 66.1 1.0 N A:CYS13 4.1 63.4 1.0 N A:HIS34 4.2 48.2 1.0 CD2 A:HIS34 4.2 52.6 1.0 NE2 A:HIS34 4.3 53.8 1.0 CA A:HIS34 4.3 49.9 1.0 CA A:CYS13 4.3 66.5 1.0 CA A:CYS11 4.6 56.4 1.0 CA A:CYS37 4.6 61.0 1.0 N A:ILE12 4.7 58.2 1.0 OG1 A:THR15 4.7 68.1 1.0 CG1 A:ILE12 4.7 61.5 1.0 C A:CYS11 4.8 58.2 1.0 N A:CYS37 4.9 60.6 1.0 O A:HIS34 4.9 50.1 1.0

Zinc binding site 2 out of 2 in the Crystal Structure of Bptf Phd-Linker-Bromo in Complex with Histone H4K12AC Peptide


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Crystal Structure of Bptf Phd-Linker-Bromo in Complex with Histone H4K12AC Peptide within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn176 b:42.4 occ:1.00 SG A:CYS26 2.3 39.9 1.0 SG A:CYS56 2.3 42.9 1.0 SG A:CYS29 2.3 42.6 1.0 SG A:CYS53 2.3 42.8 1.0 CB A:CYS56 3.2 44.5 1.0 CB A:CYS26 3.2 40.5 1.0 CB A:CYS29 3.3 43.4 1.0 CB A:CYS53 3.5 44.0 1.0 N A:CYS29 3.7 42.4 1.0 OH A:TYR33 4.0 45.2 1.0 N A:CYS53 4.0 43.5 1.0 CA A:CYS29 4.1 43.8 1.0 O A:HOH206 4.1 8.2 1.0 CA A:CYS53 4.3 44.2 1.0 CA A:CYS56 4.3 45.4 1.0 N A:CYS56 4.4 46.5 1.0 CB A:ARG28 4.4 42.1 1.0 CE2 A:TYR33 4.6 41.6 1.0 CA A:CYS26 4.6 41.4 1.0 CZ A:TYR33 4.7 42.2 1.0 C A:ARG28 4.7 43.2 1.0 O A:CYS53 4.8 45.6 1.0 C A:CYS53 4.8 45.3 1.0 C A:CYS29 4.9 45.1 1.0 CA A:ARG28 5.0 42.9 1.0

A.J.Ruthenburg, H.Li, T.A.Milne, S.Dewell, R.K.Mcginty, M.Yuen, B.Ueberheide, Y.Dou, T.W.Muir, D.J.Patel, C.D.Allis. Recognition of A Mononucleosomal Histone Modification Pattern By Bptf Via Multivalent Interactions. Cell(Cambridge,Mass.) V. 145 692 2011.
ISSN: ISSN 0092-8674
PubMed: 21596426
DOI: 10.1016/J.CELL.2011.03.053