Zinc in PDB 3qn9: Crystal Structure of A 6-Pyruvoyltetrahydropterin Synthase Homologue From Esherichia Coli

All present enzymatic activity of Crystal Structure of A 6-Pyruvoyltetrahydropterin Synthase Homologue From Esherichia Coli:
4.2.3.12;

The structure of Crystal Structure of A 6-Pyruvoyltetrahydropterin Synthase Homologue From Esherichia Coli, PDB code: 3qn9 was solved by K.H.Seo, N.N.Zhuang, K.H.Lee, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	48.75 / 2.93
Space group	P 3 2 1
Cell size a, b, c (Å), α, β, γ (°)	112.589, 112.589, 68.818, 90.00, 90.00, 120.00
R / Rfree (%)	20.4 / 26.5

The binding sites of Zinc atom in the Crystal Structure of A 6-Pyruvoyltetrahydropterin Synthase Homologue From Esherichia Coli (pdb code 3qn9). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Crystal Structure of A 6-Pyruvoyltetrahydropterin Synthase Homologue From Esherichia Coli, PDB code: 3qn9:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Crystal Structure of A 6-Pyruvoyltetrahydropterin Synthase Homologue From Esherichia Coli


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure of A 6-Pyruvoyltetrahydropterin Synthase Homologue From Esherichia Coli within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn122 b:62.2 occ:1.00 NE2 A:HIS33 2.1 60.4 1.0 NE2 A:HIS31 2.1 54.8 1.0 NE2 A:HIS16 2.2 50.7 1.0 CE1 A:HIS16 3.0 51.1 1.0 CE1 A:HIS33 3.0 61.8 1.0 CD2 A:HIS31 3.1 55.2 1.0 CE1 A:HIS31 3.1 55.5 1.0 CD2 A:HIS33 3.1 56.6 1.0 CD2 A:HIS16 3.3 51.2 1.0 OE1 A:GLU110 3.9 75.6 1.0 ND1 A:HIS33 4.1 58.9 1.0 ND1 A:HIS16 4.2 48.8 1.0 ND1 A:HIS31 4.2 54.7 1.0 CG A:HIS31 4.2 56.3 1.0 CG A:HIS33 4.2 55.1 1.0 CE1 B:HIS71 4.3 61.3 1.0 CG A:HIS16 4.4 51.0 1.0 SG A:CYS27 4.4 62.7 1.0 CD A:GLU110 4.5 74.8 1.0 OE2 A:GLU110 4.5 75.2 1.0 ND1 B:HIS71 4.8 60.9 1.0

Zinc binding site 2 out of 2 in the Crystal Structure of A 6-Pyruvoyltetrahydropterin Synthase Homologue From Esherichia Coli


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Crystal Structure of A 6-Pyruvoyltetrahydropterin Synthase Homologue From Esherichia Coli within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn122 b:67.3 occ:1.00 NE2 B:HIS31 2.0 53.3 1.0 NE2 B:HIS33 2.1 55.3 1.0 NE2 B:HIS16 2.3 53.8 1.0 CE1 B:HIS31 2.9 55.4 1.0 OE1 B:GLU110 2.9 78.6 1.0 CE1 B:HIS33 2.9 58.5 1.0 CE1 B:HIS16 3.0 52.2 1.0 CD2 B:HIS31 3.0 55.6 1.0 CD2 B:HIS33 3.3 53.2 1.0 CD2 B:HIS16 3.4 52.6 1.0 CD1 B:LEU18 3.9 59.1 1.0 CD B:GLU110 4.0 76.5 1.0 ND1 B:HIS31 4.0 55.3 1.0 ND1 B:HIS33 4.1 56.7 1.0 CG B:HIS31 4.1 55.9 1.0 ND1 B:HIS16 4.2 51.1 1.0 SG B:CYS27 4.2 57.9 1.0 CG B:HIS33 4.3 52.8 1.0 CG B:HIS16 4.4 53.0 1.0 OE2 B:GLU110 4.4 78.2 1.0 NE2 A:HIS71 4.5 60.3 1.0 CD2 A:HIS71 4.8 58.2 1.0

K.H.Seo, N.Zhuang, Y.S.Park, K.H.Park, K.H.Lee. Structural Basis of A Novel Activity of Bacterial 6-Pyruvoyltetrahydropterin Synthase Homologues Distinct From Mammalian 6-Pyruvoyltetrahydropterin Synthase Activity. Acta Crystallogr.,Sect.D V. 70 1212 2014.
ISSN: ISSN 0907-4449
PubMed: 24816091
DOI: 10.1107/S1399004714002016