Zinc in PDB 3ncu: Structural and Functional Insights Into Pattern Recognition By the Innate Immune Receptor Rig-I

The structure of Structural and Functional Insights Into Pattern Recognition By the Innate Immune Receptor Rig-I, PDB code: 3ncu was solved by G.Sheng, H.Li, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	39.03 / 2.55
Space group	P 65
Cell size a, b, c (Å), α, β, γ (°)	83.462, 83.462, 110.364, 90.00, 90.00, 120.00
R / Rfree (%)	19 / 22.9

The binding sites of Zinc atom in the Structural and Functional Insights Into Pattern Recognition By the Innate Immune Receptor Rig-I (pdb code 3ncu). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Structural and Functional Insights Into Pattern Recognition By the Innate Immune Receptor Rig-I, PDB code: 3ncu:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Structural and Functional Insights Into Pattern Recognition By the Innate Immune Receptor Rig-I


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Structural and Functional Insights Into Pattern Recognition By the Innate Immune Receptor Rig-I within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn1 b:53.5 occ:1.00 SG A:CYS869 2.2 36.2 1.0 SG A:CYS813 2.3 30.8 1.0 SG A:CYS810 2.3 29.0 1.0 SG A:CYS864 2.4 34.3 1.0 CB A:CYS810 3.1 27.5 1.0 CB A:CYS864 3.1 30.7 1.0 CB A:CYS813 3.3 31.6 1.0 CB A:CYS869 3.3 40.5 1.0 N A:CYS813 3.7 30.0 1.0 CA A:CYS813 4.0 33.8 1.0 CB A:HIS871 4.4 33.0 1.0 CB A:ARG866 4.4 45.5 1.0 CB A:LYS812 4.5 30.0 1.0 CA A:CYS810 4.6 29.9 1.0 CZ2 A:TRP873 4.6 26.0 1.0 CA A:CYS864 4.6 33.5 1.0 NE1 A:TRP873 4.7 25.5 1.0 CA A:CYS869 4.7 43.1 1.0 C A:CYS813 4.7 32.4 1.0 C A:LYS812 4.7 34.4 1.0 CG A:ARG866 4.8 49.4 1.0 N A:LYS814 4.9 33.8 1.0 N A:HIS871 4.9 30.7 1.0 CB A:ALA815 4.9 35.1 1.0

Zinc binding site 2 out of 2 in the Structural and Functional Insights Into Pattern Recognition By the Innate Immune Receptor Rig-I


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Structural and Functional Insights Into Pattern Recognition By the Innate Immune Receptor Rig-I within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn2 b:55.8 occ:1.00 SG B:CYS864 2.2 31.2 1.0 SG B:CYS813 2.3 32.2 1.0 SG B:CYS810 2.4 26.2 1.0 SG B:CYS869 2.4 35.3 1.0 CB B:CYS810 3.1 27.5 1.0 CB B:CYS864 3.1 29.5 1.0 CB B:CYS813 3.2 27.5 1.0 CB B:CYS869 3.5 46.3 1.0 N B:CYS813 3.8 26.9 1.0 CA B:CYS813 4.0 30.2 1.0 CB B:ARG866 4.3 47.1 1.0 CG B:ARG866 4.5 45.8 1.0 CB B:HIS871 4.6 33.4 1.0 CA B:CYS864 4.6 31.6 1.0 CZ2 B:TRP873 4.6 29.7 1.0 CA B:CYS810 4.6 30.1 1.0 C B:CYS813 4.7 31.4 1.0 CB B:ALA815 4.8 32.0 1.0 NE1 B:TRP873 4.8 28.8 1.0 C B:LYS812 4.8 35.1 1.0 CA B:CYS869 4.9 45.2 1.0 N B:LYS814 4.9 32.9 1.0 N B:HIS871 4.9 35.3 1.0 CB B:LYS812 4.9 29.4 1.0 N B:SER870 5.0 35.1 1.0

Y.Wang, J.Ludwig, C.Schuberth, M.Goldeck, M.Schlee, H.Li, S.Juranek, G.Sheng, R.Micura, T.Tuschl, G.Hartmann, D.J.Patel. Structural and Functional Insights Into 5'-Ppp Rna Pattern Recognition By the Innate Immune Receptor Rig-I. Nat.Struct.Mol.Biol. V. 17 781 2010.
ISSN: ISSN 1545-9993
PubMed: 20581823
DOI: 10.1038/NSMB.1863