Atomistry » Zinc » PDB 3mhs-3mpu » 3mk5
Atomistry »
  Zinc »
    PDB 3mhs-3mpu »
      3mk5 »

Zinc in PDB 3mk5: Crystal Structure of 3,4-Dihydroxy-2-Butanone 4-Phosphate Synthase Domain From Mycobacterium Tuberculosis with Sulfate and Zinc at pH 4.00

Enzymatic activity of Crystal Structure of 3,4-Dihydroxy-2-Butanone 4-Phosphate Synthase Domain From Mycobacterium Tuberculosis with Sulfate and Zinc at pH 4.00

All present enzymatic activity of Crystal Structure of 3,4-Dihydroxy-2-Butanone 4-Phosphate Synthase Domain From Mycobacterium Tuberculosis with Sulfate and Zinc at pH 4.00:
4.1.99.12;

Protein crystallography data

The structure of Crystal Structure of 3,4-Dihydroxy-2-Butanone 4-Phosphate Synthase Domain From Mycobacterium Tuberculosis with Sulfate and Zinc at pH 4.00, PDB code: 3mk5 was solved by M.Singh, S.Karthikeyan, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 34.69 / 2.06
Space group P 61
Cell size a, b, c (Å), α, β, γ (°) 65.442, 65.442, 87.740, 90.00, 90.00, 120.00
R / Rfree (%) 19.2 / 23.6

Zinc Binding Sites:

The binding sites of Zinc atom in the Crystal Structure of 3,4-Dihydroxy-2-Butanone 4-Phosphate Synthase Domain From Mycobacterium Tuberculosis with Sulfate and Zinc at pH 4.00 (pdb code 3mk5). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Crystal Structure of 3,4-Dihydroxy-2-Butanone 4-Phosphate Synthase Domain From Mycobacterium Tuberculosis with Sulfate and Zinc at pH 4.00, PDB code: 3mk5:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in 3mk5

Go back to Zinc Binding Sites List in 3mk5
Zinc binding site 1 out of 2 in the Crystal Structure of 3,4-Dihydroxy-2-Butanone 4-Phosphate Synthase Domain From Mycobacterium Tuberculosis with Sulfate and Zinc at pH 4.00


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure of 3,4-Dihydroxy-2-Butanone 4-Phosphate Synthase Domain From Mycobacterium Tuberculosis with Sulfate and Zinc at pH 4.00 within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Zn210

b:72.4
occ:1.00
 ND1 A:HIS144 2.2 29.5 1.0
O3 A:SO4207 2.6 51.7 1.0
CE1 A:HIS144 3.1 29.5 1.0
O4 A:SO4207 3.2 52.0 1.0
CG A:HIS144 3.3 26.4 1.0
S A:SO4207 3.4 51.3 1.0
CB A:HIS144 3.6 25.0 1.0
O1 A:SO4207 4.1 51.4 1.0
OD1 A:ASP33 4.2 33.0 1.0
NE2 A:HIS144 4.3 29.9 1.0
OD2 A:ASP33 4.3 33.7 1.0
OD1 A:ASP24 4.3 52.9 1.0
CD2 A:HIS144 4.3 28.2 1.0
N A:HIS144 4.5 25.0 1.0
CG A:ASP33 4.5 31.8 1.0
O2 A:SO4207 4.7 49.5 1.0
OD2 A:ASP24 4.7 50.9 1.0
CA A:HIS144 4.7 24.3 1.0
CG A:ASP24 4.8 49.9 1.0

Zinc binding site 2 out of 2 in 3mk5

Go back to Zinc Binding Sites List in 3mk5
Zinc binding site 2 out of 2 in the Crystal Structure of 3,4-Dihydroxy-2-Butanone 4-Phosphate Synthase Domain From Mycobacterium Tuberculosis with Sulfate and Zinc at pH 4.00


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Crystal Structure of 3,4-Dihydroxy-2-Butanone 4-Phosphate Synthase Domain From Mycobacterium Tuberculosis with Sulfate and Zinc at pH 4.00 within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Zn211

b:0.2
occ:1.00
 O A:HOH286 2.8 49.6 1.0
ND1 A:HIS188 2.9 32.1 1.0
CE1 A:HIS188 3.8 30.9 1.0
CG A:HIS188 3.9 29.6 1.0
CE1 A:PHE48 4.0 28.4 1.0
O A:HOH305 4.0 53.4 1.0
CB A:HIS188 4.0 29.7 1.0
CD1 A:PHE48 4.2 30.8 1.0
O A:HOH281 4.4 50.4 1.0
CA A:HIS188 4.5 29.3 1.0
CZ A:PHE48 4.9 29.8 1.0
NE2 A:HIS188 5.0 31.2 1.0
O A:HIS188 5.0 29.4 1.0

Reference:

M.Singh, P.Kumar, S.Karthikeyan. Structural Basis For pH Dependent Monomer-Dimer Transition of 3,4-Dihydroxy 2-Butanone-4-Phosphate Synthase Domain From Mycobacterium Tuberculosis J.Struct.Biol. V. 174 374 2011.
ISSN: ISSN 1047-8477
PubMed: 21296160
DOI: 10.1016/J.JSB.2011.01.013
Page generated: Wed Dec 16 04:35:27 2020

Last articles

Zn in 8WB0
Zn in 8WAX
Zn in 8WAU
Zn in 8WAZ
Zn in 8WAY
Zn in 8WAV
Zn in 8WAW
Zn in 8WAT
Zn in 8W7M
Zn in 8WD3
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy