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Atomistry » Zinc » PDB 3l2r-3ljg » 3lea | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Zinc » PDB 3l2r-3ljg » 3lea » |
Zinc in PDB 3lea: Crystal Structure of the Catalytic Domain of Tace with Isoindolinone- Biphenyl-Hydantoin InhibitorEnzymatic activity of Crystal Structure of the Catalytic Domain of Tace with Isoindolinone- Biphenyl-Hydantoin Inhibitor
All present enzymatic activity of Crystal Structure of the Catalytic Domain of Tace with Isoindolinone- Biphenyl-Hydantoin Inhibitor:
3.4.24.86; Protein crystallography data
The structure of Crystal Structure of the Catalytic Domain of Tace with Isoindolinone- Biphenyl-Hydantoin Inhibitor, PDB code: 3lea
was solved by
P.Orth,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Zinc Binding Sites:
The binding sites of Zinc atom in the Crystal Structure of the Catalytic Domain of Tace with Isoindolinone- Biphenyl-Hydantoin Inhibitor
(pdb code 3lea). This binding sites where shown within
5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Crystal Structure of the Catalytic Domain of Tace with Isoindolinone- Biphenyl-Hydantoin Inhibitor, PDB code: 3lea: Jump to Zinc binding site number: 1; 2; Zinc binding site 1 out of 2 in 3leaGo back to Zinc Binding Sites List in 3lea
Zinc binding site 1 out
of 2 in the Crystal Structure of the Catalytic Domain of Tace with Isoindolinone- Biphenyl-Hydantoin Inhibitor
Mono view Stereo pair view
Zinc binding site 2 out of 2 in 3leaGo back to Zinc Binding Sites List in 3lea
Zinc binding site 2 out
of 2 in the Crystal Structure of the Catalytic Domain of Tace with Isoindolinone- Biphenyl-Hydantoin Inhibitor
Mono view Stereo pair view
Reference:
W.Yu,
L.Tong,
S.H.Kim,
M.K.Wong,
L.Chen,
D.Y.Yang,
B.B.Shankar,
B.J.Lavey,
G.Zhou,
A.Kosinski,
R.Rizvi,
D.Li,
R.J.Feltz,
J.J.Piwinski,
K.E.Rosner,
N.Y.Shih,
M.A.Siddiqui,
Z.Guo,
P.Orth,
H.Shah,
J.Sun,
S.Umland,
D.J.Lundell,
X.Niu,
J.A.Kozlowski.
Biaryl Substituted Hydantoin Compounds As Tace Inhibitors. Bioorg.Med.Chem.Lett. V. 20 5286 2010.
Page generated: Sat Oct 26 08:29:48 2024
ISSN: ISSN 0960-894X PubMed: 20663669 DOI: 10.1016/J.BMCL.2010.06.134 |
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