Zinc in PDB 3f6g: Crystal Structure of the Regulatory Domain of Licms in Complexed with Isoleucine - Type II

All present enzymatic activity of Crystal Structure of the Regulatory Domain of Licms in Complexed with Isoleucine - Type II:
2.3.1.182;

The structure of Crystal Structure of the Regulatory Domain of Licms in Complexed with Isoleucine - Type II, PDB code: 3f6g was solved by P.Zhang, J.Ma, G.Zhao, J.Ding, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	20.00 / 2.00
Space group	C 1 2 1
Cell size a, b, c (Å), α, β, γ (°)	61.315, 97.943, 39.974, 90.00, 91.38, 90.00
R / Rfree (%)	22.6 / 26.3

The binding sites of Zinc atom in the Crystal Structure of the Regulatory Domain of Licms in Complexed with Isoleucine - Type II (pdb code 3f6g). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Crystal Structure of the Regulatory Domain of Licms in Complexed with Isoleucine - Type II, PDB code: 3f6g:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Crystal Structure of the Regulatory Domain of Licms in Complexed with Isoleucine - Type II


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure of the Regulatory Domain of Licms in Complexed with Isoleucine - Type II within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn358 b:23.7 occ:0.50 O B:HOH104 2.4 41.4 1.0 NE2 B:HIS408 2.4 25.9 1.0 ND1 B:HIS400 3.2 42.1 1.0 CD2 B:HIS408 3.3 23.4 1.0 CE1 B:HIS408 3.4 25.3 1.0 CB B:HIS400 3.8 33.4 1.0 CG B:HIS400 3.9 39.9 1.0 O B:HOH102 4.1 42.9 1.0 CE1 B:HIS400 4.2 44.2 1.0 CG B:HIS408 4.5 24.2 1.0 ND1 B:HIS408 4.5 25.5 1.0

Zinc binding site 2 out of 2 in the Crystal Structure of the Regulatory Domain of Licms in Complexed with Isoleucine - Type II


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Crystal Structure of the Regulatory Domain of Licms in Complexed with Isoleucine - Type II within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn359 b:35.1 occ:0.50 NE2 A:HIS408 2.6 27.4 1.0 O A:HOH143 2.9 48.2 1.0 ND1 A:HIS400 3.1 46.1 1.0 CE1 A:HIS408 3.5 27.4 1.0 CD2 A:HIS408 3.5 23.8 1.0 CE1 A:HIS400 3.9 47.3 1.0 CG A:HIS400 3.9 41.4 1.0 CB A:HIS400 4.2 36.2 1.0 ND1 A:HIS408 4.6 26.7 1.0 CG A:HIS408 4.7 24.0 1.0 CE1 B:HIS400 4.9 44.2 1.0 NE2 A:HIS400 4.9 44.3 1.0 CD2 A:HIS400 5.0 42.6 1.0

P.Zhang, J.Ma, Z.Zhang, M.Zha, H.Xu, G.Zhao, J.Ding. Molecular Basis of the Inhibitor Selectivity and Insights Into the Feedback Inhibition Mechanism of Citramalate Synthase From Leptospira Interrogans Biochem.J. V. 421 133 2009.
ISSN: ISSN 0264-6021
PubMed: 19351325
DOI: 10.1042/BJ20090336