|
Atomistry » Zinc » PDB 3eb6-3ejt » 3edz | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Zinc » PDB 3eb6-3ejt » 3edz » |
Zinc in PDB 3edz: Crystal Structure of Catalytic Domain of Tace with Hydroxamate InhibitorEnzymatic activity of Crystal Structure of Catalytic Domain of Tace with Hydroxamate Inhibitor
All present enzymatic activity of Crystal Structure of Catalytic Domain of Tace with Hydroxamate Inhibitor:
3.4.24.86; Protein crystallography data
The structure of Crystal Structure of Catalytic Domain of Tace with Hydroxamate Inhibitor, PDB code: 3edz
was solved by
R.D.Mazzola,
Z.Zhu,
L.Sinning,
B.Mckittrick,
B.Lavey,
J.Spitler,
J.Kozlowski,
S.Neng-Yang,
G.Zhou,
Z.Guo,
P.Orth,
V.Madison,
J.Sun,
D.Lundell,
X.Niu,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Zinc Binding Sites:
The binding sites of Zinc atom in the Crystal Structure of Catalytic Domain of Tace with Hydroxamate Inhibitor
(pdb code 3edz). This binding sites where shown within
5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Crystal Structure of Catalytic Domain of Tace with Hydroxamate Inhibitor, PDB code: 3edz: Jump to Zinc binding site number: 1; 2; Zinc binding site 1 out of 2 in 3edzGo back to![]() ![]()
Zinc binding site 1 out
of 2 in the Crystal Structure of Catalytic Domain of Tace with Hydroxamate Inhibitor
![]() Mono view ![]() Stereo pair view
Zinc binding site 2 out of 2 in 3edzGo back to![]() ![]()
Zinc binding site 2 out
of 2 in the Crystal Structure of Catalytic Domain of Tace with Hydroxamate Inhibitor
![]() Mono view ![]() Stereo pair view
Reference:
R.D.Mazzola,
Z.Zhu,
L.Sinning,
B.Mckittrick,
B.Lavey,
J.Spitler,
J.Kozlowski,
S.Neng-Yang,
G.Zhou,
Z.Guo,
P.Orth,
V.Madison,
J.Sun,
D.Lundell,
X.Niu.
Discovery of Novel Hydroxamates As Highly Potent Tumor Necrosis Factor-Alpha Converting Enzyme Inhibitors. Part II: Optimization of the S3' Pocket. Bioorg.Med.Chem.Lett. V. 18 5809 2008.
Page generated: Wed Dec 16 04:15:43 2020
ISSN: ISSN 0960-894X PubMed: 18835710 DOI: 10.1016/J.BMCL.2008.09.045 |
Last articlesZn in 7NN0Zn in 7NIO Zn in 7LUP Zn in 7M1Y Zn in 7LO4 Zn in 7KWO Zn in 7KJY Zn in 7KCQ Zn in 7KC2 Zn in 7KCB |
© Copyright 2008-2020 by atomistry.com | ||
Home | Site Map | Copyright | Contact us | Privacy |