Zinc in PDB 3d4b: Crystal Structure of SIR2TM in Complex with Acetyl P53 Peptide and Dadme-Nad+

The structure of Crystal Structure of SIR2TM in Complex with Acetyl P53 Peptide and Dadme-Nad+, PDB code: 3d4b was solved by W.F.Hawse, K.G.Hoff, D.Fatkins, A.Daines, O.V.Zubkova, V.L.Schramm, W.Zheng, C.Wolberger, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	50.00 / 1.90
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	45.790, 59.735, 106.114, 90.00, 90.00, 90.00
R / Rfree (%)	19.5 / 22.9

The binding sites of Zinc atom in the Crystal Structure of SIR2TM in Complex with Acetyl P53 Peptide and Dadme-Nad+ (pdb code 3d4b). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Crystal Structure of SIR2TM in Complex with Acetyl P53 Peptide and Dadme-Nad+, PDB code: 3d4b:

Zinc binding site 1 out of 1 in the Crystal Structure of SIR2TM in Complex with Acetyl P53 Peptide and Dadme-Nad+


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure of SIR2TM in Complex with Acetyl P53 Peptide and Dadme-Nad+ within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn1001 b:43.8 occ:1.00 SG A:CYS127 2.2 44.7 1.0 SG A:CYS148 2.3 43.4 1.0 SG A:CYS151 2.4 47.4 1.0 SG A:CYS124 2.4 36.7 1.0 CB A:CYS124 3.1 34.7 1.0 CB A:CYS148 3.1 43.7 1.0 CB A:CYS127 3.4 42.0 1.0 CB A:CYS151 3.6 49.2 1.0 N A:CYS127 3.8 41.8 1.0 N A:CYS151 3.9 50.2 1.0 CA A:CYS127 4.1 42.4 1.0 CA A:CYS151 4.3 48.9 1.0 CA A:CYS124 4.5 33.9 1.0 CA A:CYS148 4.6 43.9 1.0 CB A:ASP150 4.6 50.9 1.0 CB A:LYS129 4.6 39.5 1.0 C A:CYS151 4.7 48.9 1.0 C A:CYS127 4.8 42.2 1.0 C A:ASP150 4.8 51.0 1.0 N A:GLU128 4.8 42.1 1.0 CB A:ARG126 4.8 40.7 1.0 CB A:SER153 4.9 42.8 1.0 N A:ASN152 4.9 48.4 1.0 N A:SER153 4.9 44.6 1.0 OG A:SER153 5.0 45.0 1.0 C A:ARG126 5.0 41.4 1.0 N A:ASP150 5.0 50.8 1.0

W.F.Hawse, K.G.Hoff, D.G.Fatkins, A.Daines, O.V.Zubkova, V.L.Schramm, W.Zheng, C.Wolberger. Structural Insights Into Intermediate Steps in the SIR2 Deacetylation Reaction. Structure V. 16 1368 2008.
ISSN: ISSN 0969-2126
PubMed: 18786399
DOI: 10.1016/J.STR.2008.05.015