The binding sites of Zinc atom in the structure of Binary Complex of The Mixed Lineage Leukaemia (MLL1) Set Domain With the Cofactor Product S-Adenosylhomocysteine. (pdb code 2w5y). This binding sites where shown with 5.0 Angstroms radius around Zinc atom. The 2w5y structure was solved by S.M.SOUTHALL, P.S.WONG, Z.ODHO, S.M.ROE, J.R.WILSON, with X-Ray Crystallography technique, brief refinement statistics is given in the table below:
Resolution (A) | 23.7-2.0 | Space group | P212121 | a (A) | 48.850 | b (A) | 56.210 | c (A) | 78.240 | alpha (°) | 90.00 | beta (°) | 90.00 | gamma (°) | 90.00 | Rfactor (%) | 18.7 | Rfree (%) | 26.4 |
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Zinc binding site 1 out of 1 in 2w5y
|  Click to enlarge |  Click to enlarge | Mono- and Stereo- picture of 5.0 Angstrom coordination sphere 1 of Zinc in the PDB 2w5y. Coordination sphere was calculated for all residues within 5.0 Angstroms distance from the central Zinc atom, shown by VdW sphere Residues shown as a stick model or VDW spheres: A: His3907, A: Ser3908, A: Cys3909, A: Cys3957, A: Cys3959, A: Ala3961, A: Cys3964, A: Arg3965, A: Lys3966, A: Hoh2129, | conact list:
Atom | Atom | Distance (A) | Zn | NE2 A:His3907 | 4.37 | Zn | CD2 A:His3907 | 4.53 | Zn | C A:Ser3908 | 4.80 | Zn | CA A:Ser3908 | 4.97 | Zn | N A:Cys3909 | 3.78 | Zn | CB A:Cys3909 | 3.44 | Zn | SG A:Cys3909 | 2.52 | Zn | CA A:Cys3909 | 4.25 | Zn | O A:Cys3957 | 4.74 | Zn | CB A:Cys3957 | 3.47 | Zn | SG A:Cys3957 | 2.29 | Zn | C A:Cys3957 | 4.68 | Zn | CA A:Cys3957 | 4.70 | Zn | O A:Cys3959 | 4.67 | Zn | N A:Cys3959 | 4.14 | Zn | CB A:Cys3959 | 3.50 | Zn | SG A:Cys3959 | 2.42 | Zn | C A:Cys3959 | 4.74 | Zn | CA A:Cys3959 | 4.29 | Zn | CB A:Ala3961 | 4.60 | Zn | CB A:Cys3964 | 3.54 | Zn | SG A:Cys3964 | 2.66 | Zn | C A:Cys3964 | 4.32 | Zn | CA A:Cys3964 | 3.76 | Zn | N A:Arg3965 | 3.87 | Zn | CA A:Arg3965 | 4.96 | Zn | N A:Lys3966 | 4.54 | Zn | O A:Hoh2129 | 4.37 |
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