Zinc in PDB 2v0p: The Structure of TAP42 ALPHA4 Subunit

The structure of The Structure of TAP42 ALPHA4 Subunit, PDB code: 2v0p was solved by S.M.Roe, J.Yang, D.Barford, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	71.07 / 1.80
Space group	P 1
Cell size a, b, c (Å), α, β, γ (°)	44.633, 48.308, 71.960, 81.31, 87.94, 69.83
R / Rfree (%)	23.8 / 25.6

The binding sites of Zinc atom in the The Structure of TAP42 ALPHA4 Subunit (pdb code 2v0p). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 4 binding sites of Zinc where determined in the The Structure of TAP42 ALPHA4 Subunit, PDB code: 2v0p:
Jump to Zinc binding site number: 1; 2; 3; 4;

Zinc binding site 1 out of 4 in the The Structure of TAP42 ALPHA4 Subunit


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of The Structure of TAP42 ALPHA4 Subunit within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn1235 b:81.7 occ:1.00 SG A:CYS182 1.4 43.7 1.0 CB A:CYS182 3.0 40.4 1.0 CA A:CYS182 3.7 40.0 1.0 N A:CYS182 4.4 40.4 1.0 CD1 A:LEU185 4.7 47.5 1.0

Zinc binding site 2 out of 4 in the The Structure of TAP42 ALPHA4 Subunit


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of The Structure of TAP42 ALPHA4 Subunit within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn1236 b:34.5 occ:1.00 SG A:CYS226 2.3 36.1 1.0 CB A:CYS226 3.1 33.8 1.0 O A:HOH2086 3.6 40.5 1.0 CA A:CYS226 4.5 35.3 1.0 N A:LYS105 4.6 29.2 1.0 O A:LEU101 4.6 32.5 1.0 CA A:LYS105 4.6 32.7 1.0 CB A:LYS105 4.6 33.2 1.0 CD2 A:LEU223 4.8 34.1 1.0 C A:CYS226 4.9 36.8 1.0 NZ A:LYS105 4.9 54.5 1.0 CB A:LEU104 5.0 30.0 1.0

Zinc binding site 3 out of 4 in the The Structure of TAP42 ALPHA4 Subunit


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 3 of The Structure of TAP42 ALPHA4 Subunit within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn1235 b:52.1 occ:1.00 SG B:CYS182 2.6 37.9 1.0 CB B:CYS182 3.0 32.2 1.0 CA B:CYS182 4.1 32.2 1.0 O B:HOH2077 4.7 59.8 1.0

Zinc binding site 4 out of 4 in the The Structure of TAP42 ALPHA4 Subunit


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 4 of The Structure of TAP42 ALPHA4 Subunit within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn1236 b:66.8 occ:1.00 SG B:CYS226 2.1 39.4 1.0 CB B:CYS226 3.1 38.2 1.0 C B:CYS226 3.5 37.6 1.0 O B:CYS226 3.6 37.4 1.0 CA B:CYS226 3.9 37.0 1.0 N B:GLU227 3.9 38.6 1.0 OG B:SER230 4.0 48.2 1.0 CA B:GLU227 4.4 39.6 1.0 O B:LEU223 4.6 27.0 1.0 CG B:GLU227 4.6 42.0 1.0 CD2 B:LEU101 4.9 35.0 1.0

J.Yang, S.M.Roe, T.D.Prickett, D.L.Brautigan, D.Barford. The Structure of TAP42/ALPHA4 Reveals A Tetratricopeptide Repeat-Like Fold and Provides Insights Into PP2A Regulation. Biochemistry V. 46 8807 2007.
ISSN: ISSN 0006-2960
PubMed: 17616149
DOI: 10.1021/BI7007118