Atomistry » Zinc » PDB 2pop-2q1q » 2pu1
Atomistry »
  Zinc »
    PDB 2pop-2q1q »
      2pu1 »

Zinc in PDB 2pu1: Crystal Structure of the T. Brucei Enolase Complexed with Fluoro-Phosphonoacetohydroxamate (Fpah)

Enzymatic activity of Crystal Structure of the T. Brucei Enolase Complexed with Fluoro-Phosphonoacetohydroxamate (Fpah)

All present enzymatic activity of Crystal Structure of the T. Brucei Enolase Complexed with Fluoro-Phosphonoacetohydroxamate (Fpah):
4.2.1.11;

Protein crystallography data

The structure of Crystal Structure of the T. Brucei Enolase Complexed with Fluoro-Phosphonoacetohydroxamate (Fpah), PDB code: 2pu1 was solved by M.V.A.S.Navarro, D.J.Rigden, R.C.Garratt, S.M.G.Dias, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 21.04 / 1.80
Space group C 2 2 21
Cell size a, b, c (Å), α, β, γ (°) 74.809, 110.644, 109.006, 90.00, 90.00, 90.00
R / Rfree (%) 16.2 / 20.6

Other elements in 2pu1:

The structure of Crystal Structure of the T. Brucei Enolase Complexed with Fluoro-Phosphonoacetohydroxamate (Fpah) also contains other interesting chemical elements:

Fluorine (F) 2 atoms

Zinc Binding Sites:

The binding sites of Zinc atom in the Crystal Structure of the T. Brucei Enolase Complexed with Fluoro-Phosphonoacetohydroxamate (Fpah) (pdb code 2pu1). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 3 binding sites of Zinc where determined in the Crystal Structure of the T. Brucei Enolase Complexed with Fluoro-Phosphonoacetohydroxamate (Fpah), PDB code: 2pu1:
Jump to Zinc binding site number: 1; 2; 3;

Zinc binding site 1 out of 3 in 2pu1

Go back to Zinc Binding Sites List in 2pu1
Zinc binding site 1 out of 3 in the Crystal Structure of the T. Brucei Enolase Complexed with Fluoro-Phosphonoacetohydroxamate (Fpah)


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure of the T. Brucei Enolase Complexed with Fluoro-Phosphonoacetohydroxamate (Fpah) within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Zn500

b:21.2
occ:1.00
OE2 A:GLU291 2.0 17.5 1.0
OD2 A:ASP318 2.1 16.8 1.0
O A:HOH759 2.1 19.5 1.0
O3 A:FSG600 2.1 19.3 0.5
OD2 A:ASP243 2.1 16.5 1.0
O3 A:FSG600 2.2 16.1 0.5
O2 A:FSG600 2.5 15.6 0.5
O2 A:FSG600 2.5 17.7 0.5
N3 A:FSG600 2.9 16.6 0.5
C2 A:FSG600 3.0 16.6 0.5
N3 A:FSG600 3.0 16.2 0.5
CG A:ASP243 3.0 19.6 1.0
C2 A:FSG600 3.1 17.5 0.5
CG A:ASP318 3.1 17.4 1.0
CD A:GLU291 3.1 19.7 1.0
OD1 A:ASP243 3.3 16.9 1.0
CB A:ASP318 3.7 18.1 1.0
NZ A:LYS394 3.7 17.2 1.0
OE1 A:GLU291 3.8 20.9 1.0
NZ A:LYS343 3.8 15.4 1.0
O A:HOH727 3.9 18.8 1.0
O A:HOH817 3.9 19.5 1.0
OE1 A:GLN164 4.0 23.9 1.0
OD2 A:ASP292 4.1 20.6 1.0
CD2 A:LEU341 4.1 17.4 1.0
OD1 A:ASP318 4.1 20.9 1.0
ZN A:ZN501 4.2 21.9 1.0
CG A:GLU291 4.2 18.1 1.0
CB A:ASP243 4.4 21.1 1.0
C1 A:FSG600 4.5 15.6 0.5
C1 A:FSG600 4.6 17.9 0.5
OE2 A:GLU165 4.7 21.3 1.0
F A:FSG600 4.9 20.7 0.5
CE A:LYS394 4.9 18.4 1.0
CG A:ASP292 4.9 21.6 1.0
CE A:LYS343 4.9 13.3 1.0

Zinc binding site 2 out of 3 in 2pu1

Go back to Zinc Binding Sites List in 2pu1
Zinc binding site 2 out of 3 in the Crystal Structure of the T. Brucei Enolase Complexed with Fluoro-Phosphonoacetohydroxamate (Fpah)


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Crystal Structure of the T. Brucei Enolase Complexed with Fluoro-Phosphonoacetohydroxamate (Fpah) within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Zn501

b:21.9
occ:1.00
O A:SER40 2.1 20.2 1.0
O A:HOH817 2.1 19.5 1.0
O2P A:FSG600 2.1 18.2 0.5
O2P A:FSG600 2.1 18.3 0.5
O A:HOH727 2.1 18.8 1.0
O2 A:FSG600 2.2 15.6 0.5
OG A:SER40 2.3 17.5 1.0
O2 A:FSG600 2.3 17.7 0.5
C2 A:FSG600 2.9 16.6 0.5
C A:SER40 3.0 20.4 1.0
CB A:SER40 3.1 20.6 1.0
C2 A:FSG600 3.1 17.5 0.5
P A:FSG600 3.2 16.1 0.5
P A:FSG600 3.3 17.9 0.5
C1 A:FSG600 3.3 15.6 0.5
CA A:SER40 3.5 20.4 1.0
F A:FSG600 3.5 20.7 0.5
C1 A:FSG600 3.5 17.9 0.5
O3P A:FSG600 3.9 18.5 0.5
OD2 A:ASP319 3.9 21.7 1.0
OD2 A:ASP318 3.9 16.8 1.0
O3P A:FSG600 4.0 19.1 0.5
N A:SER40 4.0 20.1 1.0
OD1 A:ASP319 4.0 22.9 1.0
O A:HOH759 4.1 19.5 1.0
N3 A:FSG600 4.1 16.6 0.5
NZ A:LYS343 4.1 15.4 1.0
ZN A:ZN500 4.2 21.2 1.0
N A:THR41 4.2 21.3 1.0
NH2 A:ARG372 4.2 13.7 1.0
N3 A:FSG600 4.2 16.2 0.5
NE2 A:GLN164 4.4 21.0 1.0
CG A:ASP319 4.4 19.9 1.0
O1P A:FSG600 4.4 15.4 0.5
O1P A:FSG600 4.4 19.1 0.5
OE1 A:GLN164 4.5 23.9 1.0
CA A:THR41 4.6 20.9 1.0
F A:FSG600 4.6 15.3 0.5
O3 A:FSG600 4.6 19.3 0.5
O3 A:FSG600 4.7 16.1 0.5
CD A:GLN164 4.9 24.8 1.0
CG A:ASP318 4.9 17.4 1.0

Zinc binding site 3 out of 3 in 2pu1

Go back to Zinc Binding Sites List in 2pu1
Zinc binding site 3 out of 3 in the Crystal Structure of the T. Brucei Enolase Complexed with Fluoro-Phosphonoacetohydroxamate (Fpah)


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 3 of Crystal Structure of the T. Brucei Enolase Complexed with Fluoro-Phosphonoacetohydroxamate (Fpah) within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Zn550

b:33.5
occ:0.50
OE2 A:GLU27 2.0 30.7 1.0
ND1 A:HIS0 2.3 55.0 1.0
O A:HOH1042 2.7 45.1 1.0
CD A:GLU27 2.7 33.6 1.0
OE1 A:GLU27 2.9 35.0 1.0
CE1 A:HIS0 3.0 56.3 1.0
CG A:HIS0 3.5 52.5 1.0
CB A:HIS0 4.0 49.3 1.0
NE2 A:HIS0 4.2 56.0 1.0
CG A:GLU27 4.2 30.4 1.0
CD2 A:HIS0 4.4 55.7 1.0
O A:HIS0 4.4 44.3 1.0
CG A:MET1 4.7 44.3 1.0
CB A:GLU27 4.7 29.1 1.0
C A:HIS0 4.7 45.3 1.0

Reference:

M.V.Navarro, S.M.Gomes Dias, L.V.Mello, M.T.Da Silva Giotto, S.Gavalda, C.Blonski, R.C.Garratt, D.J.Rigden. Structural Flexibility in Trypanosoma Brucei Enolase Revealed By X-Ray Crystallography and Molecular Dynamics. Febs J. V. 274 5077 2007.
ISSN: ISSN 1742-464X
PubMed: 17822439
DOI: 10.1111/J.1742-4658.2007.06027.X
Page generated: Wed Dec 16 03:49:08 2020

Last articles

Zn in 8WB0
Zn in 8WAX
Zn in 8WAU
Zn in 8WAZ
Zn in 8WAY
Zn in 8WAV
Zn in 8WAW
Zn in 8WAT
Zn in 8W7M
Zn in 8WD3
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy