Zinc in PDB 2lwr: Solution Structure of RING2 Domain From Parkin

The binding sites of Zinc atom in the Solution Structure of RING2 Domain From Parkin (pdb code 2lwr). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Solution Structure of RING2 Domain From Parkin, PDB code: 2lwr:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Solution Structure of RING2 Domain From Parkin


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Solution Structure of RING2 Domain From Parkin within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn1 b:0.0 occ:1.00 SG A:CYS454 2.3 0.0 1.0 SG A:CYS439 2.3 0.0 1.0 SG A:CYS459 2.3 0.0 1.0 SG A:CYS436 2.3 0.0 1.0 HB2 A:CYS439 3.1 0.0 1.0 HB3 A:CYS454 3.1 0.0 1.0 CB A:CYS454 3.1 0.0 1.0 H A:CYS439 3.1 0.0 1.0 HB2 A:CYS436 3.1 0.0 1.0 HB2 A:CYS454 3.2 0.0 1.0 CB A:CYS436 3.2 0.0 1.0 HB2 A:CYS459 3.3 0.0 1.0 CB A:CYS439 3.3 0.0 1.0 CB A:CYS459 3.3 0.0 1.0 HB3 A:CYS436 3.4 0.0 1.0 HD3 A:ARG456 3.4 0.0 1.0 HB3 A:CYS459 3.4 0.0 1.0 HH11 A:ARG456 3.5 0.0 1.0 HB3 A:ARG456 3.6 0.0 1.0 HB2 A:LYS438 3.7 0.0 1.0 HB3 A:PHE461 3.8 0.0 1.0 N A:CYS439 3.9 0.0 1.0 HG1 A:THR441 4.0 0.0 1.0 OG1 A:THR441 4.0 0.0 1.0 HB3 A:CYS439 4.1 0.0 1.0 CA A:CYS439 4.3 0.0 1.0 H A:PHE461 4.3 0.0 1.0 H A:LYS438 4.3 0.0 1.0 HB2 A:PHE461 4.4 0.0 1.0 CD A:ARG456 4.4 0.0 1.0 NH1 A:ARG456 4.5 0.0 1.0 HB2 A:ARG456 4.5 0.0 1.0 CB A:ARG456 4.5 0.0 1.0 HD2 A:ARG456 4.5 0.0 1.0 CA A:CYS454 4.6 0.0 1.0 CB A:PHE461 4.6 0.0 1.0 H A:ARG440 4.7 0.0 1.0 CA A:CYS436 4.7 0.0 1.0 HD2 A:PRO437 4.7 0.0 1.0 CB A:LYS438 4.7 0.0 1.0 H A:THR441 4.8 0.0 1.0 H A:ARG456 4.8 0.0 1.0 CA A:CYS459 4.8 0.0 1.0 H A:GLY460 4.9 0.0 1.0 HH12 A:ARG456 4.9 0.0 1.0 HB3 A:LYS438 4.9 0.0 1.0 HA A:CYS454 4.9 0.0 1.0 HA A:CYS439 5.0 0.0 1.0 HA A:CYS459 5.0 0.0 1.0

Zinc binding site 2 out of 2 in the Solution Structure of RING2 Domain From Parkin


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Solution Structure of RING2 Domain From Parkin within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn2 b:0.0 occ:1.00 SG A:CYS475 2.2 0.0 1.0 SG A:CYS464 2.2 0.0 1.0 SG A:CYS467 2.2 0.0 1.0 NE2 A:HIS479 2.5 0.0 1.0 CE1 A:HIS479 2.5 0.0 1.0 HE1 A:HIS479 2.7 0.0 1.0 HB2 A:CYS467 2.8 0.0 1.0 HB A:THR472 2.9 0.0 1.0 ND1 A:HIS479 3.1 0.0 1.0 CD2 A:HIS479 3.1 0.0 1.0 CB A:CYS467 3.1 0.0 1.0 HB2 A:CYS464 3.3 0.0 1.0 CB A:CYS464 3.5 0.0 1.0 CG A:HIS479 3.5 0.0 1.0 CB A:CYS475 3.7 0.0 1.0 OG1 A:THR472 3.7 0.0 1.0 H A:CYS467 3.7 0.0 1.0 HD1 A:HIS479 3.7 0.0 1.0 CB A:THR472 3.7 0.0 1.0 HB2 A:CYS475 3.7 0.0 1.0 HB3 A:CYS467 3.7 0.0 1.0 HD2 A:HIS479 3.8 0.0 1.0 H A:THR472 3.9 0.0 1.0 O A:CYS464 3.9 0.0 1.0 HG1 A:THR472 4.1 0.0 1.0 HB3 A:CYS464 4.1 0.0 1.0 HB3 A:CYS475 4.1 0.0 1.0 N A:CYS467 4.3 0.0 1.0 CA A:CYS467 4.3 0.0 1.0 HB A:VAL466 4.4 0.0 1.0 HG23 A:THR472 4.4 0.0 1.0 HB2 A:HIS479 4.6 0.0 1.0 H A:CYS475 4.6 0.0 1.0 CA A:CYS464 4.6 0.0 1.0 CB A:HIS479 4.6 0.0 1.0 N A:THR472 4.7 0.0 1.0 CG2 A:THR472 4.7 0.0 1.0 O A:THR472 4.7 0.0 1.0 C A:CYS464 4.7 0.0 1.0 CA A:THR472 4.7 0.0 1.0 CA A:CYS475 4.8 0.0 1.0 H A:CYS464 4.9 0.0 1.0 HA A:CYS467 4.9 0.0 1.0 HB3 A:HIS479 5.0 0.0 1.0

D.E.Spratt, R.Julio Martinez-Torres, Y.J.Noh, P.Mercier, N.Manczyk, K.R.Barber, J.D.Aguirre, L.Burchell, A.Purkiss, H.Walden, G.S.Shaw. A Molecular Explanation For the Recessive Nature of Parkin-Linked Parkinson'S Disease. Nat Commun V. 4 1983 2013.
ISSN: ESSN 2041-1723
PubMed: 23770917
DOI: 10.1038/NCOMMS2983