Zinc in PDB 2lgk: uc(Nmr) Structure of UHRF1 Phd Domains in A Complex with Histone H3 Peptide

The binding sites of Zinc atom in the uc(Nmr) Structure of UHRF1 Phd Domains in A Complex with Histone H3 Peptide (pdb code 2lgk). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 3 binding sites of Zinc where determined in the uc(Nmr) Structure of UHRF1 Phd Domains in A Complex with Histone H3 Peptide, PDB code: 2lgk:
Jump to Zinc binding site number: 1; 2; 3;

Zinc binding site 1 out of 3 in the uc(Nmr) Structure of UHRF1 Phd Domains in A Complex with Histone H3 Peptide


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of uc(Nmr) Structure of UHRF1 Phd Domains in A Complex with Histone H3 Peptide within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn380 b:0.0 occ:1.00 SG A:CYS329 2.3 0.0 1.0 SG A:CYS315 2.3 0.0 1.0 SG A:CYS318 2.3 0.0 1.0 SG A:CYS326 2.3 0.0 1.0 H A:CYS329 2.9 0.0 1.0 HB A:VAL328 3.0 0.0 1.0 HB3 A:CYS326 3.1 0.0 1.0 HB3 A:CYS318 3.2 0.0 1.0 HB3 A:CYS329 3.2 0.0 1.0 CB A:CYS315 3.3 0.0 1.0 CB A:CYS326 3.3 0.0 1.0 CB A:CYS329 3.3 0.0 1.0 HB3 A:CYS315 3.4 0.0 1.0 CB A:CYS318 3.4 0.0 1.0 N A:CYS329 3.4 0.0 1.0 HB2 A:CYS315 3.4 0.0 1.0 HB2 A:CYS326 3.9 0.0 1.0 CA A:CYS329 4.0 0.0 1.0 HB2 A:CYS318 4.0 0.0 1.0 CB A:VAL328 4.0 0.0 1.0 HG12 A:VAL328 4.2 0.0 1.0 H A:CYS318 4.2 0.0 1.0 HB2 A:CYS329 4.2 0.0 1.0 C A:VAL328 4.3 0.0 1.0 H A:VAL328 4.4 0.0 1.0 O A:CYS326 4.4 0.0 1.0 CA A:CYS326 4.5 0.0 1.0 CA A:CYS318 4.5 0.0 1.0 CA A:VAL328 4.6 0.0 1.0 CG1 A:VAL328 4.6 0.0 1.0 C A:CYS326 4.6 0.0 1.0 O A:CYS329 4.6 0.0 1.0 N A:VAL328 4.6 0.0 1.0 H A:CYS326 4.7 0.0 1.0 C A:CYS329 4.7 0.0 1.0 CA A:CYS315 4.7 0.0 1.0 N A:CYS318 4.7 0.0 1.0 HG13 A:VAL328 4.8 0.0 1.0 C A:CYS318 4.8 0.0 1.0 HA A:CYS315 4.8 0.0 1.0 HA A:VAL322 4.8 0.0 1.0 O A:CYS318 4.9 0.0 1.0 HA A:CYS329 4.9 0.0 1.0 N A:CYS326 4.9 0.0 1.0 HG23 A:VAL328 5.0 0.0 1.0

Zinc binding site 2 out of 3 in the uc(Nmr) Structure of UHRF1 Phd Domains in A Complex with Histone H3 Peptide


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of uc(Nmr) Structure of UHRF1 Phd Domains in A Complex with Histone H3 Peptide within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn381 b:0.0 occ:1.00 NE2 A:HIS354 2.0 0.0 1.0 SG A:CYS334 2.3 0.0 1.0 SG A:CYS331 2.3 0.0 1.0 SG A:CYS357 2.3 0.0 1.0 CD2 A:HIS354 2.3 0.0 1.0 HD2 A:HIS354 2.5 0.0 1.0 H A:CYS334 2.7 0.0 1.0 CE1 A:HIS354 3.0 0.0 1.0 HB3 A:CYS334 3.3 0.0 1.0 CB A:CYS331 3.3 0.0 1.0 H A:GLY335 3.4 0.0 1.0 CB A:CYS334 3.4 0.0 1.0 CG A:HIS354 3.4 0.0 1.0 HB3 A:CYS331 3.4 0.0 1.0 CB A:CYS357 3.4 0.0 1.0 HB3 A:CYS357 3.5 0.0 1.0 HB2 A:CYS331 3.5 0.0 1.0 HB2 A:LEU333 3.5 0.0 1.0 N A:CYS334 3.5 0.0 1.0 HE1 A:HIS354 3.6 0.0 1.0 HA A:HIS354 3.6 0.0 1.0 HB2 A:CYS357 3.7 0.0 1.0 ND1 A:HIS354 3.7 0.0 1.0 H A:GLY336 4.0 0.0 1.0 CA A:CYS334 4.0 0.0 1.0 OH A:TYR356 4.1 0.0 1.0 H A:LEU333 4.2 0.0 1.0 N A:GLY335 4.2 0.0 1.0 HE1 A:TYR356 4.2 0.0 1.0 HB2 A:CYS334 4.3 0.0 1.0 CZ A:TYR356 4.5 0.0 1.0 CA A:HIS354 4.5 0.0 1.0 CE1 A:TYR356 4.5 0.0 1.0 HD1 A:HIS354 4.6 0.0 1.0 CB A:LEU333 4.6 0.0 1.0 CB A:HIS354 4.6 0.0 1.0 C A:CYS334 4.6 0.0 1.0 C A:LEU333 4.6 0.0 1.0 CA A:CYS331 4.7 0.0 1.0 HH A:TYR356 4.7 0.0 1.0 N A:LEU333 4.8 0.0 1.0 CA A:CYS357 4.8 0.0 1.0 HE21 A:GLN338 4.8 0.0 1.0 N A:GLY336 4.9 0.0 1.0 CA A:LEU333 4.9 0.0 1.0 HA A:CYS334 4.9 0.0 1.0 HA A:CYS357 5.0 0.0 1.0 H A:CYS357 5.0 0.0 1.0

Zinc binding site 3 out of 3 in the uc(Nmr) Structure of UHRF1 Phd Domains in A Complex with Histone H3 Peptide


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 3 of uc(Nmr) Structure of UHRF1 Phd Domains in A Complex with Histone H3 Peptide within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn382 b:0.0 occ:1.00 SG A:CYS376 2.3 0.0 1.0 SG A:CYS349 2.3 0.0 1.0 SG A:CYS373 2.3 0.0 1.0 SG A:CYS346 2.3 0.0 1.0 H A:CYS373 2.9 0.0 1.0 HB2 A:GLU348 3.2 0.0 1.0 H A:CYS349 3.3 0.0 1.0 HB2 A:CYS376 3.3 0.0 1.0 HB2 A:CYS349 3.3 0.0 1.0 HB3 A:CYS373 3.4 0.0 1.0 CB A:CYS376 3.4 0.0 1.0 CB A:CYS349 3.5 0.0 1.0 CB A:CYS373 3.5 0.0 1.0 CB A:CYS346 3.5 0.0 1.0 H A:CYS376 3.6 0.0 1.0 HB3 A:CYS346 3.6 0.0 1.0 HB2 A:CYS346 3.7 0.0 1.0 N A:CYS373 3.7 0.0 1.0 N A:CYS349 3.8 0.0 1.0 N A:CYS376 4.1 0.0 1.0 CA A:CYS373 4.1 0.0 1.0 HB3 A:GLU375 4.1 0.0 1.0 CB A:GLU348 4.2 0.0 1.0 CA A:CYS349 4.3 0.0 1.0 HB3 A:CYS376 4.3 0.0 1.0 HB3 A:TYR372 4.3 0.0 1.0 CA A:CYS376 4.3 0.0 1.0 HB3 A:CYS349 4.3 0.0 1.0 HZ A:PHE353 4.3 0.0 1.0 HB2 A:CYS373 4.3 0.0 1.0 O A:CYS373 4.4 0.0 1.0 HA A:CYS376 4.4 0.0 1.0 HB3 A:GLU348 4.5 0.0 1.0 HA A:TYR372 4.5 0.0 1.0 H A:GLU348 4.5 0.0 1.0 HE1 A:PHE353 4.5 0.0 1.0 C A:GLU348 4.6 0.0 1.0 HD1 A:TYR372 4.6 0.0 1.0 OE1 A:GLU348 4.6 0.0 1.0 C A:CYS373 4.7 0.0 1.0 C A:TYR372 4.8 0.0 1.0 HA A:CYS349 4.8 0.0 1.0 CA A:GLU348 4.8 0.0 1.0 CA A:CYS346 4.8 0.0 1.0 N A:GLU348 4.9 0.0 1.0 CZ A:PHE353 5.0 0.0 1.0

C.Wang, J.Shen, Z.Yang, P.Chen, B.Zhao, W.Hu, W.Lan, X.Tong, H.Wu, G.Li, C.Cao. Structural Basis For Site-Specific Reading of Unmodified R2 of Histone H3 Tail By UHRF1 Phd Finger. Cell Res. V. 21 1379 2011.
ISSN: ISSN 1001-0602
PubMed: 21808299
DOI: 10.1038/CR.2011.123