Zinc in PDB 2l6z: Haddock Model of GATA1NF:LMO2LIM2-LDB1LID with Fog

The binding sites of Zinc atom in the Haddock Model of GATA1NF:LMO2LIM2-LDB1LID with Fog (pdb code 2l6z). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 4 binding sites of Zinc where determined in the Haddock Model of GATA1NF:LMO2LIM2-LDB1LID with Fog, PDB code: 2l6z:
Jump to Zinc binding site number: 1; 2; 3; 4;

Zinc binding site 1 out of 4 in the Haddock Model of GATA1NF:LMO2LIM2-LDB1LID with Fog


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Haddock Model of GATA1NF:LMO2LIM2-LDB1LID with Fog within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn239 b:0.5 occ:1.00 SG A:CYS225 2.2 0.5 1.0 SG A:CYS228 2.3 0.6 1.0 SG A:CYS207 2.3 0.6 1.0 SG A:CYS204 2.3 0.5 1.0 HB2 A:CYS228 3.0 0.6 1.0 H A:CYS207 3.0 0.5 1.0 HB3 A:CYS225 3.0 0.4 1.0 H A:CYS228 3.1 0.6 1.0 CB A:CYS228 3.2 0.6 1.0 CB A:CYS225 3.3 0.4 1.0 HB3 A:CYS207 3.3 0.7 1.0 CB A:CYS204 3.3 0.4 1.0 CB A:CYS207 3.3 0.6 1.0 H A:CYS225 3.4 0.4 1.0 HB2 A:CYS204 3.4 0.4 1.0 HB3 A:CYS204 3.5 0.5 1.0 H A:GLY208 3.5 0.5 1.0 N A:CYS207 3.5 0.6 1.0 H A:ASN206 3.8 0.5 1.0 N A:CYS228 3.9 0.6 1.0 CA A:CYS207 4.0 0.6 1.0 HB3 A:ASN206 4.0 0.8 1.0 HB2 A:CYS225 4.0 0.5 1.0 HB3 A:CYS228 4.0 0.7 1.0 H A:ALA209 4.1 0.5 1.0 HB3 A:ALA227 4.1 0.9 1.0 H A:ASN226 4.1 0.5 1.0 N A:CYS225 4.2 0.4 1.0 CA A:CYS228 4.2 0.7 1.0 HB2 A:ASN206 4.2 0.7 1.0 HB2 A:CYS207 4.3 0.7 1.0 N A:GLY208 4.3 0.5 1.0 CA A:CYS225 4.4 0.4 1.0 C A:ASN206 4.4 0.6 1.0 H A:ALA227 4.4 0.6 1.0 CB A:ASN206 4.5 0.7 1.0 N A:ASN206 4.6 0.5 1.0 C A:CYS207 4.6 0.6 1.0 HB1 A:ALA209 4.7 0.5 1.0 CA A:ASN206 4.7 0.6 1.0 H A:VAL205 4.7 0.4 1.0 CA A:CYS204 4.8 0.4 1.0 H A:GLY229 4.8 0.6 1.0 HA A:CYS207 4.9 0.7 1.0 HA A:LEU224 4.9 0.4 1.0 HA A:CYS228 5.0 0.7 1.0

Zinc binding site 2 out of 4 in the Haddock Model of GATA1NF:LMO2LIM2-LDB1LID with Fog


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Haddock Model of GATA1NF:LMO2LIM2-LDB1LID with Fog within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn37 b:0.9 occ:1.00 NE2 B:HIS27 1.9 0.8 1.0 SG B:CYS11 2.3 1.0 1.0 SG B:CYS14 2.3 1.0 1.0 SG B:CYS32 2.3 1.0 1.0 CD2 B:HIS27 2.8 0.8 1.0 HD2 B:HIS27 3.0 0.8 1.0 CE1 B:HIS27 3.0 0.8 1.0 HA B:CYS32 3.1 1.1 1.0 HB2 B:CYS14 3.1 0.9 1.0 HB2 B:CYS11 3.3 1.1 1.0 HE1 B:HIS27 3.3 0.9 1.0 CB B:CYS14 3.3 0.9 1.0 CB B:CYS11 3.3 1.1 1.0 CB B:CYS32 3.4 1.0 1.0 CA B:CYS32 3.6 1.0 1.0 HB3 B:CYS11 3.6 1.3 1.0 HB3 B:CYS14 3.7 0.8 1.0 HB3 B:TYR31 3.8 0.9 1.0 HB3 B:CYS32 3.8 1.1 1.0 N B:CYS32 3.8 0.9 1.0 CG B:HIS27 4.0 0.8 1.0 H B:CYS32 4.0 0.9 1.0 ND1 B:HIS27 4.0 0.8 1.0 H B:CYS14 4.1 1.1 1.0 H B:CYS11 4.2 1.0 1.0 HB2 B:CYS32 4.3 1.0 1.0 C B:TYR31 4.5 0.9 1.0 HA B:GLN28 4.6 0.9 1.0 CA B:CYS14 4.6 1.0 1.0 CA B:CYS11 4.7 1.1 1.0 N B:CYS14 4.7 1.1 1.0 HH11 B:ARG35 4.8 1.0 1.0 O B:TYR31 4.8 1.0 1.0 HD13 B:LEU24 4.9 0.9 1.0 O B:HIS27 4.9 0.8 1.0 CB B:TYR31 4.9 0.8 1.0 N B:CYS11 4.9 1.0 1.0 HD2 B:PRO13 4.9 1.2 1.0 HD1 B:HIS27 5.0 0.8 1.0

Zinc binding site 3 out of 4 in the Haddock Model of GATA1NF:LMO2LIM2-LDB1LID with Fog


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 3 of Haddock Model of GATA1NF:LMO2LIM2-LDB1LID with Fog within 5.0Å range: probe atom residue distance (Å) B Occ C:Zn180 b:0.6 occ:1.00 ND1 C:HIS116 2.0 0.6 1.0 SG C:CYS94 2.3 0.7 1.0 SG C:CYS97 2.3 0.7 1.0 SG C:CYS119 2.3 0.6 1.0 HB2 C:HIS116 2.8 0.6 1.0 CE1 C:HIS116 2.9 0.7 1.0 CG C:HIS116 3.0 0.6 1.0 HB2 C:CYS94 3.0 0.8 1.0 HE1 C:HIS116 3.1 0.7 1.0 H C:CYS97 3.1 0.7 1.0 CB C:CYS94 3.2 0.8 1.0 HB3 C:CYS97 3.3 0.7 1.0 HB2 C:CYS119 3.4 0.6 1.0 CB C:CYS119 3.4 0.6 1.0 CB C:CYS97 3.4 0.7 1.0 CB C:HIS116 3.4 0.6 1.0 HB3 C:CYS94 3.5 0.8 1.0 HB3 C:CYS119 3.6 0.6 1.0 HB2 C:SER96 3.7 0.7 1.0 N C:CYS97 3.8 0.7 1.0 NE2 C:HIS116 4.1 0.7 1.0 HB2 C:LYS99 4.1 0.8 1.0 CD2 C:HIS116 4.1 0.7 1.0 CA C:CYS97 4.1 0.7 1.0 H C:SER96 4.1 0.7 1.0 HB3 C:HIS116 4.1 0.6 1.0 HB2 C:CYS97 4.3 0.7 1.0 N C:HIS116 4.3 0.6 1.0 H C:HIS116 4.4 0.7 1.0 H C:LYS99 4.5 0.9 1.0 CA C:HIS116 4.5 0.5 1.0 HG3 C:GLU118 4.6 0.9 1.0 HA C:TYR115 4.6 0.7 1.0 CA C:CYS94 4.6 0.8 1.0 CB C:SER96 4.7 0.7 1.0 C C:CYS97 4.7 0.7 1.0 H C:CYS119 4.7 0.6 1.0 C C:TYR115 4.7 0.6 1.0 C C:SER96 4.7 0.7 1.0 H C:ALA95 4.8 0.8 1.0 HA C:CYS94 4.8 0.8 1.0 CA C:CYS119 4.8 0.5 1.0 O C:CYS97 4.9 0.9 1.0 HB3 C:SER96 4.9 0.7 1.0 N C:SER96 4.9 0.7 1.0 HE2 C:HIS116 4.9 0.8 1.0 HB3 C:TYR115 5.0 0.7 1.0

Zinc binding site 4 out of 4 in the Haddock Model of GATA1NF:LMO2LIM2-LDB1LID with Fog


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 4 of Haddock Model of GATA1NF:LMO2LIM2-LDB1LID with Fog within 5.0Å range: probe atom residue distance (Å) B Occ C:Zn181 b:0.3 occ:1.00 OD2 C:ASP147 2.0 0.4 1.0 SG C:CYS122 2.3 0.3 1.0 SG C:CYS125 2.3 0.4 1.0 SG C:CYS144 2.3 0.3 1.0 H C:CYS125 2.7 0.4 1.0 CG C:ASP147 2.9 0.4 1.0 HB3 C:CYS144 3.1 0.3 1.0 H C:CYS144 3.1 0.3 1.0 OD1 C:ASP147 3.3 0.4 1.0 HB2 C:CYS122 3.3 0.3 1.0 CB C:CYS122 3.3 0.3 1.0 HB3 C:CYS125 3.3 0.5 1.0 CB C:CYS144 3.3 0.3 1.0 CB C:CYS125 3.4 0.5 1.0 HB3 C:CYS122 3.4 0.3 1.0 HB1 C:ALA124 3.4 0.4 1.0 HE21 C:GLN146 3.5 1.6 1.0 N C:CYS125 3.5 0.4 1.0 H C:ASP147 3.6 0.3 1.0 HB3 C:GLN146 3.9 0.5 1.0 N C:CYS144 4.0 0.2 1.0 CA C:CYS125 4.0 0.5 1.0 H C:GLN126 4.0 0.4 1.0 NE2 C:GLN146 4.0 1.3 1.0 H C:LYS127 4.1 0.5 1.0 H C:ALA124 4.1 0.4 1.0 HG13 C:VAL143 4.1 0.6 1.0 CB C:ASP147 4.1 0.4 1.0 HB2 C:CYS144 4.1 0.3 1.0 HE22 C:GLN146 4.2 1.6 1.0 HB3 C:ASP147 4.2 0.4 1.0 HB2 C:LYS127 4.2 0.4 1.0 HB2 C:CYS125 4.3 0.5 1.0 CA C:CYS144 4.3 0.2 1.0 N C:ASP147 4.4 0.3 1.0 CB C:ALA124 4.5 0.5 1.0 H C:GLN146 4.5 0.3 1.0 N C:GLN126 4.6 0.4 1.0 HA C:VAL143 4.6 0.3 1.0 C C:ALA124 4.7 0.5 1.0 C C:CYS125 4.7 0.4 1.0 CA C:CYS122 4.7 0.3 1.0 CA C:ASP147 4.8 0.3 1.0 N C:ALA124 4.8 0.4 1.0 CA C:ALA124 4.9 0.5 1.0 HD2 C:LYS127 4.9 1.3 1.0 HB2 C:ASP147 4.9 0.4 1.0 CB C:GLN146 4.9 0.4 1.0 HA C:CYS125 4.9 0.5 1.0 CD C:GLN146 5.0 0.8 1.0 HG3 C:LYS127 5.0 1.0 1.0 HA C:CYS122 5.0 0.3 1.0

L.Wilkinson-White, R.Gamsjaeger, S.Dastmalchi, B.Wienert, P.H.Stokes, M.Crossley, J.P.Mackay, J.M.Matthews. Structural Basis of Simultaneous Recruitment of the Transcriptional Regulators LMO2 and FOG1/ZFPM1 By the Transcription Factor GATA1 Proc.Natl.Acad.Sci.Usa V. 108 14443 2011.
ISSN: ISSN 0027-8424
PubMed: 21844373
DOI: 10.1073/PNAS.1105898108