Zinc in PDB 2fa7: Crystal Structure of the Complex of Bovine Lactoferrin C-Lobe with A Pentasaccharide at 2.38 A Resolution

The structure of Crystal Structure of the Complex of Bovine Lactoferrin C-Lobe with A Pentasaccharide at 2.38 A Resolution, PDB code: 2fa7 was solved by N.Singh, R.Jain, T.Jabeen, S.Sharma, A.Bhushan, T.P.Singh, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	62.02 / 2.38
Space group	P 1 21 1
Cell size a, b, c (Å), α, β, γ (°)	62.960, 50.499, 65.859, 90.00, 107.50, 90.00
R / Rfree (%)	19.8 / 23.6

The structure of Crystal Structure of the Complex of Bovine Lactoferrin C-Lobe with A Pentasaccharide at 2.38 A Resolution also contains other interesting chemical elements:

Iron

(Fe)

1 atom

The binding sites of Zinc atom in the Crystal Structure of the Complex of Bovine Lactoferrin C-Lobe with A Pentasaccharide at 2.38 A Resolution (pdb code 2fa7). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 3 binding sites of Zinc where determined in the Crystal Structure of the Complex of Bovine Lactoferrin C-Lobe with A Pentasaccharide at 2.38 A Resolution, PDB code: 2fa7:
Jump to Zinc binding site number: 1; 2; 3;

Zinc binding site 1 out of 3 in the Crystal Structure of the Complex of Bovine Lactoferrin C-Lobe with A Pentasaccharide at 2.38 A Resolution


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure of the Complex of Bovine Lactoferrin C-Lobe with A Pentasaccharide at 2.38 A Resolution within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn302 b:31.1 occ:1.00 O A:HOH775 2.1 33.9 1.0 OE2 A:GLU659 2.2 29.2 1.0 OE1 A:GLU659 2.3 28.1 1.0 CD A:GLU659 2.5 26.2 1.0 O A:GLY653 3.8 31.1 1.0 CG A:GLU659 4.1 24.2 1.0 O A:ARG654 4.3 28.5 1.0 O6 A:NAG689 4.5 59.5 1.0 CA A:PRO655 4.9 25.6 1.0 N A:THR656 4.9 23.5 1.0 CB A:GLU659 4.9 23.3 1.0 C A:ARG654 5.0 28.2 1.0 C A:GLY653 5.0 30.9 1.0

Zinc binding site 2 out of 3 in the Crystal Structure of the Complex of Bovine Lactoferrin C-Lobe with A Pentasaccharide at 2.38 A Resolution


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Crystal Structure of the Complex of Bovine Lactoferrin C-Lobe with A Pentasaccharide at 2.38 A Resolution within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn303 b:31.6 occ:1.00 O A:HOH839 1.7 46.6 1.0 O A:HOH840 1.7 25.5 1.0 NE2 A:HIS588 2.1 20.1 1.0 O A:HOH929 2.3 64.4 1.0 CE1 A:HIS588 2.9 18.4 1.0 CD2 A:HIS588 3.2 21.1 1.0 O A:HOH928 3.6 57.4 1.0 ND1 A:HIS588 4.0 19.3 1.0 CG A:HIS588 4.2 20.5 1.0 O A:HOH740 4.5 38.8 1.0

Zinc binding site 3 out of 3 in the Crystal Structure of the Complex of Bovine Lactoferrin C-Lobe with A Pentasaccharide at 2.38 A Resolution


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 3 of Crystal Structure of the Complex of Bovine Lactoferrin C-Lobe with A Pentasaccharide at 2.38 A Resolution within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn304 b:91.8 occ:0.50 NE2 A:HIS606 1.9 36.7 1.0 O A:TYR342 2.1 52.1 1.0 O A:HOH925 2.2 37.9 1.0 O A:HOH924 2.4 54.5 1.0 CD2 A:HIS606 2.6 34.4 1.0 CA A:THR343 2.7 48.2 1.0 C A:TYR342 3.0 51.6 1.0 CE1 A:HIS606 3.0 36.0 1.0 N A:THR343 3.3 50.0 1.0 CB A:THR343 3.4 48.5 1.0 N A:ARG344 3.4 43.5 1.0 CG2 A:THR343 3.6 48.7 1.0 C A:THR343 3.6 46.4 1.0 CG A:HIS606 3.8 31.8 1.0 ND1 A:HIS606 4.0 34.8 1.0 O A:HOH923 4.0 57.0 1.0 CA A:TYR342 4.3 52.9 1.0 O A:ARG344 4.5 37.8 1.0 NH2 A:ARG603 4.5 38.7 1.0 CA A:ARG344 4.7 40.7 1.0 OG1 A:THR343 4.8 49.8 1.0 O A:THR343 4.8 46.9 1.0 NH1 A:ARG603 4.8 36.0 1.0 C A:ARG344 5.0 37.9 1.0

N.Singh, R.Jain, T.Jabeen, S.Sharma, A.Bhushan, T.P.Singh. Crystal Structure of the Complex of Bovine Lactoferrin C-Lobe with A Pentasaccharide at 2.38 A Resolution To Be Published.